Podcasts by AMiNDR: A Month in Neurodegenerative Disease Research

Welcome to AMiNDR! from 2023-12-12T19:42:54.806354

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Papers published on Alzheimer's disease in February 2020: Disease Mechanisms from 2023-12-12T19:42:54.801178

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Modifiable Risk Factors: Alzheimer's Disease June 2020 (Part 1) from 2023-12-12T19:42:54.783008

Having trouble keeping up with the literature in Alzheimer's Disease? We are here to help!  

This is the first of a two-part episode, where Naila covers the papers published in June 2020 o...

Modifiable Risk Factors: Alzheimer's Disease June 2020 (Part 2) from 2023-12-12T19:42:54.778460

Having trouble keeping up with the literature in Alzheimer's Disease? We are here to help!  

You'll hear more from Naila in this episode on the papers  published in June 2020 on modifiable...

Preclinical Testing - Multi-targeted approaches and Improving Cognition: Alzheimer's Disease June 2020 from 2023-12-12T19:42:54.773480

Having trouble keeping up with the literature in Alzheimer's Disease? We are here to help!

In this episode, Anusha first covers papers on preclinical testing of multi-targeted approaches f...

Neuroinflammation&Glial Cells: Alzheimer's Disease June 2020 from 2023-12-12T19:42:54.768284

Having trouble keeping up with the literature in Alzheimer's Disease? We are here to help!

  Sarah will tell you about the AD papers from June 2020 on some of her favourite topics: neuroin...

Clinical Testing: Alzheimer's Disease June 2020 from 2023-12-12T19:42:54.741325

Having trouble keeping up with the literature in Alzheimer's Disease? We are here to help! 

In this episode, Joseph presents papers published in June 2020 where pharmacological approaches ...

Preclinical Testing - Part 2: Alzheimer's Disease June 2020 from 2023-12-12T19:42:54.737453

Having trouble keeping up with the literature in Alzheimer's Disease? We are here to help!

In this episode, Naila covers papers published in June 2020 on treatment development done on anim...

Preclinical Testing - Part 3: Alzheimer's Disease June 2020 from 2023-12-12T19:42:54.705175

Having trouble keeping up with the literature in Alzheimer's Disease? We are here to help!

In this episode, Marcia covers papers published in June 2020 on treatment development done on ani...

Novel Drugs Targeting Amyloid-Beta: Alzheimer's Disease June 2020 from 2023-12-12T19:42:54.701709

Having trouble keeping up with the literature in Alzheimer's Disease? We are here to help! Ellen tells you about papers on drugs in development targeting amyloid-beta production, aggregation, an...

29 - Amyloid-beta-mediated toxicity: Alzheimer's disease June 2020 from 2023-12-12T19:42:54.691833

Having trouble keeping up with the literature in Alzheimer's Disease? We are here to help!  

Sarah has a lot of fun hosting this highly interesting episode covering papers published in Jun...

30 - Imaging Tools for Diagnosis Part 2: Alzheimer's Disease June 2020 from 2023-12-12T19:42:54.687726

Having trouble keeping up with the literature in Alzheimer's Disease? We are here to help!  

In part 2, Bhumika tells you all about the new papers on imaging tools for AD from June 2020! Y...

37 - Cognitive Changes: Alzheimer's Disease August 2020 from 2023-12-12T19:42:54.665935

Anusha updates you on the papers from August 2020 studying cognitive and behavioural changes that occur in Alzheimer's disease and how they relate to disease mechanisms and pathology. This inclu...

38 - Risk Factors for AD Part 2: Alzheimer's Disease August 2020 from 2023-12-12T19:42:54.661008

In part 2 of our Risk Factors episodes for August 2020, Naila will go over papers on comorbidities associated with AD, hormonal factors that may explain some of the sex differences in AD risk, a...

39 - Detecting Amyloid&Tau in the Brain Part 1: Alzheimer's Disease August 2020 from 2023-12-12T19:42:54.656333

Judy is here to update you on the latest research on detecting amyloid and tau in the brain to diagnose AD in living patients, or to detect AD in post-mortem brain tissue.  This includes papers ...

40 - Risk Factors for AD Part 3: Alzheimer's Disease August 2020 from 2023-12-12T19:42:54.652063

In Part 3 of the August 2020 Risk Factors episodes, Naila will take you through research on how education and other cognitive factors can influence cognitive decline in later life, tell you abou...

41 - Neuroinflammation&Glial cells: Alzheimer's Disease August 2020 from 2023-12-12T19:42:54.647451

Heather covers papers from August 2020 on the role of neuroinflammation and glial cells on Alzheimer's disease pathology. You'll hear about many papers studying the role of astrocytes and microg...

42 - Preclinical Testing Part 1: Alzheimer's Disease August 2020 from 2023-12-12T19:42:54.644382

In Part 1 of the AD preclinical testing papers published in August 2020, Naila gets us started with some treatments that target the cholinergic system and synaptic function, tau phosphorylation ...

43 - Imaging Tools for Diagnosis Part 1: Alzheimer's Disease August 2020 from 2023-12-12T19:42:54.640019

Bhumika updates you on the new papers that use brain imaging to diagnose and study AD, in the first of two episodes on this topic! This includes new advances in MRI and PET imaging, and machine ...

44 - Preclinical Testing Part 2: Alzheimer's Disease August 2020 from 2023-12-12T19:42:54.612702

You'll hear about some big topics in Alzheimer's disease research in this episode! Ellen covers all of the pre-clinical studies from August 2020 testing potential new treatments targeting neuroi...

45 - Non-pharmacological Treatment Approaches: Alzheimer's Disease August 2020 from 2023-12-12T19:42:54.609348

In this episode, Naila takes you through peer-reviewed research published in August 2020, on the many non-pharmacological approaches to treating AD. She covers a lot of territory, from diet-base...

46 - Imaging Tools for Diagnosis Part 2: Alzheimer's Disease August 2020 from 2023-12-12T19:42:54.606219

Bhumika is back to tell you more about the latest tools and techniques in imaging to diagnosis Alzheimer's disease from papers published in August 2020. This includes PET imaging, MRI, and machi...

71 - Amyloid-beta mediated toxicity: Alzheimer's Disease September 2020 from 2023-12-12T19:42:54.513514

This episode, hosted by Jacques, explores many facets of amyloid-beta mediated toxicity. First, we run through the structure-toxicity relationships of mutant amyloid-beta. Second, we investigate...

72 - Synaptic Transmission in Alzheimer's Disease: September 2020 from 2023-12-12T19:42:54.509670

What is it about neurotransmission that is so difficult to regulate in Alzheimer's? Anusha will tell you in this episode, so tune in if you're interested in the role of cholinergic and glutamate...

73 - Risk Factors for Alzheimer's Disease Part 2: September 2020 from 2023-12-12T19:42:54.505906

In this episode, Naila goes through 13 papers that explore how benzodiazepine and anticholinergic drug use affect individuals with dementia, whether exposure to certain air pollutants increase t...

74 - Multi-Targeted Treatment Approaches for Alzheimer's Disease Part 1: September 2020 from 2023-12-12T19:42:54.502830

In this episode, Alex will be covering papers published in September 2020 within the category of novel drug development, that focus on multi-targeted approaches to Alzheimer’s disease treatment....

75 - Risk Factors in Alzheimer's Disease Part 3: September 2020 from 2023-12-12T19:42:54.498883

Naila is back to round off the non-genetic risk factors for September, with 6 papers on a variety of potential comorbidities, and 7 more on epidemiological studies and the interaction of various...

86 - Treatments Targeting the Immune System&Glia in Alzheimer's Disease: September 2020 from 2023-12-12T19:42:54.479751

Happy New Year from the AMiNDR team! In our first episode of 2021, Abdullah presents on the modulation of inflammatory response in AD, with a big emphasis on microglia, the forgotten heroes in h...

87 - Cognitive&Behavioural Changes in Alzheimer's Disease: September 2020 from 2023-12-12T19:42:54.476180

Interested in the behavioural aspects of AD such as changes to cognition, emotion, sleep, sensory and verbal abilities, and learning and memory? Look no further. Anusha will guide you through th...

88 - Non-Pharmacological Treatment Approaches for Alzheimer's Disease: September 2020 from 2023-12-12T19:42:54.472483

In today’s episode, you’ll hear about the latest developments in preventing or treating AD using non-pharmacological approaches, such as cognitive interventions, stimulation techniques, and exer...

89 - Treatments targeting amyloid-beta-mediated toxicity in Alzheimer's Disease: September 2020 from 2023-12-12T19:42:54.467058

In this episode, Marcia updates you on 8 papers from September 2020 on the development of treatments that target amyloid-beta mediated toxicity to treat Alzheimer's disease. Tune in to hear more...

90 - New Genetic Variants in Alzheimer's Disease: September 2020 from 2023-12-12T19:42:54.462418

Is the ever-expanding genetic landscape of Alzheimer’s disease overwhelming for you? Joseph will help you catch up on all the literature about new genes or variants linked to Alzheimer’s Disease...

105 - Cognitive or Clinical Indicators of Alzheimer's Disease Part 2: September 2020 from 2023-12-12T19:42:54.420064

In this episode, Courtney covers Part 2 of the papers published in September of 2020 on cognitive testing as a diagnostic tool. The topics in this part cover a wide array of topics including bra...

112 - Changes to RNA, Transcription&Translation in Alzheimer's Disease: January 2021 from 2023-12-12T19:42:54.403465

In today’s episode, Marcia brings you the latest research from Jan 2021 on changes to RNA, Transcription and Translation in the context of Alzheimer’s disease. We also talk about some really in-...

113 - Mechanisms underlying Risk Factors for Alzheimer's Disease, Part 1: January 2021 from 2023-12-12T19:42:54.400096

In this episode, Naila covers the first half of peer-reviewed papers publish in January 2021 on mechanisms underlying risk factors of Alzheimer's disease. In 11 papers, she'll go through diabete...

114 - Mechanisms underlying Risk Factors for Alzheimer's Disease, Part 2: January 2021 from 2023-12-12T19:42:54.396694

In Part 2 of mechanisms underlying AD risk factors, you'll learn about comorbidities ranging from traumatic brain injury to schizophrenia, hear a little bit about hearing loss, and be exposed to...

115 - Detection of amyloid, tau and new PET markers in Alzheimer's Disease: January 2021 from 2023-12-12T19:42:54.393605

This longer episode features amyloid and tau detection in the brain, as well as new PET targets of AD! Judy discusses papers from January 2021 that include topics such as AD mouse models, deep l...

116 - Treatments targeting the Immune System, Glia, Proteostasis&Autophagy in Alzheimer's Disease: January 2021 from 2023-12-12T19:42:54.390803

 In this episode, Abdullah will cover the latest papers from January 2021 covering development of potential treatments targeting glia, immune cells, proteostasis and autophagy. Tune in to learn ...

117 - Understanding Cognitive&Neuropsychiatric Changes in Alzheimer's Disease: January 2021 from 2023-12-12T19:42:54.387388

Ellen covers papers published this past January on cognitive and neuropsychiatric symptoms in AD and the mechanisms behind them. You'll hear about sensory processing, cognitive and memory defici...

118 - Treatments targeting Oxidative Stress, Metabolism and Mitochondria in Alzheimer's Disease: January 2021 from 2023-12-12T19:42:54.384190

In this episode, Marcia will take you through papers from January 2021 that involve research on targeting mitochondria, metabolism and oxidative stress as effective therapeutic strategies agains...

119 - Brain Imaging of Structural Changes in Alzheimer's Disease: January 2021 from 2023-12-12T19:42:54.381245

Learn about the studies from January 2021 that used imaging to investigate structural changes in Alzheimer's disease. This includes imaging of different brain regions, as well as other structure...

129 - Understanding APOE and Familial Mutations in Alzheimer's Disease: February 2021 from 2023-12-12T19:42:54.348208

In this episode, Courtney takes you through the papers from February 2021 on understanding ApoE in Alzheimer's disease and through a few papers on the familial mutations in Alzheimer's disease. ...

130 - Epidemiological Studies of Risk Factors for Alzheimer's Disease: February 2021 from 2023-12-12T19:42:54.344510

Curious about ketogenic diets, insomnia and loneliness? Then this episode is just for you! Join Naila as she goes through 23 new epidemiological studies of AD that were published in February 202...

131 - APP Processing&Aggregation in Alzheimer's Disease: February 2021 from 2023-12-12T19:42:54.340247

In this episode, Jacques runs through February 2021's papers on APP processing and amyloid-beta aggregation. Learn about key residues underlying amyloid-beta aggregation, fibrillogenesis-promoti...

132 - Changes to synaptic function and plasticity in Alzheimer's Disease: February 2021 from 2023-12-12T19:42:54.336023

Want to learn more about how changes in synaptic function, structure and plasticity are implicated in neurodegenerative disease pathology? We've got you covered with this episode! Glory will gui...

133 - Changes to RNA, Transcription&Translation in Alzheimer's Disease: February 2021 from 2023-12-12T19:42:54.329591

Marcia is back to update you on the latest Alzheimer's research. Today's episode is all about RNA, transcription, translation, proteomics, and more, all in the context of AD. Enjoy.  

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134 - Understanding Cognitive&Neuropsychiatric Changes in Alzheimer's Disease: February 2021 from 2023-12-12T19:42:54.325886

A huge focus of Alzheimer's Disease research is understanding the mechanisms behind behavioural symptoms and how to treat them. In this episode, Ellen takes you through papers published in Febru...

135 - Detection of Amyloid, Tau and new PET targets in Alzheimer's Disease: February 2021 from 2023-12-12T19:42:54.322401

Follow along with Alex in this episode, as we take a closer look at papers studying amyloid and tau PET targets in Alzheimer's Disease, as well as some new PET targets at the end of the episode....

171 - Understanding Cognitive&Behavioural Changes in Alzheimer's Disease Part 1: May 2021 from 2023-12-12T19:42:54.221572

In part one of this 2-parter, Ellen will tell you all about the latest studies on cognition and motor deficits in AD. This includes mechanistic studies, as well as studies looking at potential t...

172 - Detection of Amyloid, Tau, and other PET Targets in Alzheimer's Disease: May 2021 from 2023-12-12T19:42:54.215613

In this episode, we’ll take a closer look at 13 papers published in May 2021, that rely on Positron emission tomography imaging (or PET) to detect amyloid and tau pathology in the brain, within ...

173 - APP Processing&Amyloid-Beta Aggregation in Alzheimer's Disease: May 2021 from 2023-12-12T19:42:54.210539

Hello hello to fellow baptists, tauists and all protein aggregation enthusiasts! Sarah brings you 15 papers from the month of May on Amyloid-beta aggregation! This is the first part of a 2 episo...

174 - Understanding Cognitive&Behavioural Changes in Alzheimer's Disease Part 2: May 2021 from 2023-12-12T19:42:54.205724

In part 2 of this set of episodes, Ellen dives into papers on psychiatric changes and sleep disturbances in the context of AD. This includes research looking at depression, anxiety, agitation, c...

175 - Role of the Immune System&Glial Cells in Alzheimer's Disease: May 2021 from 2023-12-12T19:42:54.201173

In this episode, Courtney takes you through the papers from May of 2021 on the Role of Immune systems and glial cells in Alzheimer's disease pathology! We will be discussing papers related to ne...

176 - Familial Mutations, New Variants&Other Genetic Insights in Alzheimer's Disease: May 2021 from 2023-12-12T19:42:54.197313

Wow - May 2021 is a productive month for AD genetics research! Tune in and Joseph will take you through 19 papers on studies to do with new variants, novel genetic insights, or studies on famili...

177 - Treatments targeting Neurotransmitter Balance in Alzheimer's Disease: May 2021 from 2023-12-12T19:42:54.193188

This episode of AMiNDR highlights literature published in May of 2021 that target neurotransmitter balance in Alzheimer's Disease. Greatest hits include cholinesterase inhibition, targeting glut...

182 - Cognitive&Behavioural Changes in Alzheimer's Disease: June 2021 from 2023-12-12T19:42:54.183180

Ellen kicks off this series by telling you about the latest research from June 2021 on topics like cognition, memory, reading, gait, speech, depression, sleep, and even more. Learn how these sym...

183 - Changes to Gene Expression in Alzheimer's Disease: June 2021 from 2023-12-12T19:42:54.179571

We know how critical gene expression and its regulation is to cellular homeostasis. In light of that, it is imperative that we discuss the possibility that Alzheimer’s disease could be caused by...

184 - Synaptic Transmission in Alzheimer's Disease: June 2021 from 2023-12-12T19:42:54.175861

Curious about how neuronal hyperactivity and hippocampal synaptic plasticity impairment contribute to Alzheimer's pathology? Join Glory for the latest updates on research about the mechanisms of...

185 - Metabolic Changes, Hemodynamics and EEG in Alzheimer's Disease: June 2021 from 2023-12-12T19:42:54.171982

In this shorter episode, Judy goes over papers published in June 2021 that focus on diagnostic tools of Alzheimer's disease. Topics include metabolic changes, hemodynamics and EEG biomarkers. Li...

186 - Treatments targeting neuronal protection in Alzheimer's Disease: June 2021 from 2023-12-12T19:42:54.168260

Join our host Anusha as she takes you through papers published in June of 2021 that target neuroprotection as a potential treatment avenue for Alzheimer's disease. Half these papers use amyloid-...

195 - Metabolic Changes, Hemodynamics and EEG studies in Alzheimer's Disease: July 2021 from 2023-12-12T19:42:54.141675

Curious about oxidative stress, default mode network markers and EEG patterns associated with Alzheimer's disease? Join us for an exciting episode on metabolic changes, hemodynamics and EEG feat...

196 - Changes to Gene Expression in Alzheimer's Disease: July 2021 from 2023-12-12T19:42:54.137384

“Omics”, “differential expression” and “biomarker discovery” – Are these phrases you commonly use in your research? Or have you come across them and wondered what they meant in the context of AD...

197 - Synaptic transmission in Alzheimer's Disease: July 2021 from 2023-12-12T19:42:54.122485

Glory's back for another episode with all the latest updates on research about how disruptions in certain mechanisms of synaptic transmission and plasticity contribute to Alzheimer's disease. We...

198 - Understanding Cognitive&Behavioural Changes in Alzheimer's Disease: July 2021 from 2023-12-12T19:42:54.118375

Visual reaction time, japanese orange scent, language, psychosis, and insomnia are just some of the topics you’ll hear about today in this episode. Have we piqued your interest? Today Ellen tell...

207 - Treatments targeting neuroprotection&synaptic activity in Alzheimer's Disease: August 2021 from 2023-12-12T19:42:54.097298

Another month passed means another month of literature for AMiNDR to bring to you! This time, Anusha will be highlighting papers from August of 2021 that are about treatments targeting neuroprot...

208 - Prevention&Intervention Strategies in Alzheimer's Disease: August 2021 from 2023-12-12T19:42:54.093158

In this short and sweet episode, Naila covers 7 new papers on prevention and intervention of Alzheimer's disease. You'll hear about upcoming clinical trials of behavioural and cognitive interven...

209 - Treatments targeting Neurotransmission in Alzheimer's Disease: August 2021 from 2023-12-12T19:42:54.089108

This is an episode that explores the creation and testing of drugs that aim to restore neurotransmitter balance in Alzheimer's disease. It covers 14 papers that were all published in August of 2...

219 - Clinical Markers of Alzheimer's Disease Part 1: August 2021 from 2023-12-12T19:42:54.067858

Do you want to brush up on your knowledge of MoCA, ADAS-Cog, the MMSE and other cognitive tests? Join Sarah to hear about the 7 papers published in August 2021 where we’re evaluating existing te...

220 - Clinical Markers of Alzheimer's Disease Part 2: August 2021 from 2023-12-12T19:42:54.064871

This is part 2 of our episode on clinical markers for Alzheimer’s disease, where we cover papers published in August 2021. How does a translation of your favourite cognitive test perform in a Ch...

221 - Treatments Targeting Synaptic&Neuronal Protection in Alzheimer's Disease: September 2021 from 2023-12-12T19:42:54.061180

The first episode of our September 2021 series gets us acclimated with papers that target neuronal and synaptic function in preclinical studies of Azheimer's disease. Join Anusha and she walks y...

231 - Understanding Cognitive&Behavioural Changes in Alzheimer's Disease: September 2021 from 2023-12-12T19:42:54.037716

Ellen tells you about research on topics such as cognitive reserve, reinforcement learning, psychiatric conditions, sleep issues, speech,  and more in this jam-packed episode on cognitive and be...

232 - Prevention&Intervention Strategies for Alzheimer's Disease : September 2021 from 2023-12-12T19:42:54.032779

This episode is short and sweet, covering 7 papers on cognitive training, exercise and stimulation techniques. Naila will guide you through the latest in animal models and underlying mechanisms ...

233 - Clinical Markers of Alzheimer's Disease Part 1: September 2021 from 2023-12-12T19:42:54.014020

You may have come across a variety of exams used to test cognitive function and assess cognitive decline, such as the Addenbrooke's Cognitive Examination, the mini mental state exam, the clock d...

234 - Clinical Markers for Alzheimer's Disease Part 2: September 2021 from 2023-12-12T19:42:54.010338

Were you looking to learn about clinical testing for Alzheimer’s disease? This is Part 2 of our monthly episode on cognitive and clinical markers for diagnostic and prognostic purposes. Come lea...

242 - New Variants&Genetic Insights Part 2: October 2021 from 2023-12-12T19:42:53.991303

Welcome to our first episode of 2022! Marcia will bring you 13 genetics papers from October 2021. We will talk about all kinds of topics - right from AD-associated loci to polygenetic risk strat...

243 - Autophagy&Proteostasis in Alzheimer's Disease: October 2021 from 2023-12-12T19:42:53.987970

New year, new papers! Join Kate for your monthly update on all things proteostasis and autophagy as they relate to both AD pathology and potential new therapeutic interventions. In today's paper...

244 - Vascular Contributions to Alzheimer's Disease: October 2021 from 2023-12-12T19:42:53.984388

Elyn is back with your monthly update on vascular contributions to Alzheimer disease! This month she covers 8 papers that primarily focus on the blood-brain barrier, and white matter hyperintens...

254 - Tau Protein Pathology in Alzheimer's Disease: November 2021 from 2023-12-12T19:42:53.963176

Join Kate for a comprehensive summary of everything tau from papers published in November 2021.  We'll talk post-translational modifications, prion-like seeding pathology, molecular modeling, an...

255 - Treatments Targeting Neuroprotection and Neurotransmission in Alzheimer's Disease: November 2021 from 2023-12-12T19:42:53.959406

17 papers have "Targeting neurotransmission and synaptic dysfunction in AD" written all over it. Figuratively speaking of course. Anusha covers topics like targeting neurotoxicity and calcium fl...

256 - Autophagy and Proteostasis in Alzheimer's Disease: November 2021 from 2023-12-12T19:42:53.955545

Tired of only hearing about tau or a-beta when it comes to AD research? Take a peek behind the scenes with Kate to explore the latest on the proteostasis and autophagy pathways that work to safe...

265 - Treatments Targeting Neuroprotection in Alzheimer's Disease: December 2021 from 2023-12-12T19:42:53.936518

In this short and sweet episode, Anusha will take you through 7 papers published in December of 2021 on the subject of treatments targeting neuronal and synaptic protection in AD. Exercise your ...

266 - Risk Factors for Alzheimer's Disease: December 2021 from 2023-12-12T19:42:53.919908

Discover the latest on risk and protective factors of AD, from the perspective of 18 observational studies published in December 2021. Naila will take you through socioeconomic factors, nutritio...

273 - Risk Factors for Alzheimer's Disease Part 2: January 2022 from 2023-12-12T19:42:53.904036

In Part 2 of epidemiological studies published in January 2022, we'll focus on the association between cardiovascular health, diabetes and Alzheimer's disease. Naila will guide you through the l...

284 - Cognitive Assessment in Alzheimer's Disease Part 2: March 2022 from 2023-12-12T19:42:53.880625

Welcome back for the second of a 2-part episode on the clinical assessment of Alzheimer’s disease, based on abstracts published in March 2022! You will hear about the evaluation of traditional a...

291 - Vascular Contributions to Alzheimer's Disease: May 2022 from 2023-12-12T19:42:53.864950

Elyn is back with a short and sweet episode on the latest research on vascular contributions to Alzheimer disease! Tune in for a quick recap of May 2022 research, and a disease perspective a bit...

296 - Treatments Targeting Neuroprotection in Alzheimer's Disease: June 2022 from 2023-12-12T19:42:53.852860

Anusha brings you 12 papers today on the development of treatments that target neuroprotection in Alzheimer's disease. This includes a range of research models, from in silico and drug discovery...

297 - Genetic Insights for Alzheimer's Disease: June 2022 from 2023-12-12T19:42:53.849173

In this episode, Joseph covers papers published in June 2022 on GWAS studies, transcriptomics, genetic and genomic studies and the like on Alzheimer’s disease. Stay tuned!  

Sections in th...

298 - Understanding APOE and Alzheimer's Disease: June 2022 from 2023-12-12T19:42:53.845121

Approximately, one in every five people you know, has a copy of the largest genetic risk allele for late-onset Alzheimer's disease called apolipoprotein E4 (APOE). In this episode, Cassi discuss...

306 - Prevention and Intervention Strategies for Alzheimer's Disease: July 2022 from 2023-12-12T19:42:53.805269

In this episode, Naila will guide you through 14 papers on potential neuroprotective factors to mitigate the risk of Alzheimer's disease, non-pharmacological interventions that could directly ta...

307 - Cognitive&Behavioural Changes in Alzheimer's Disease Part 2: July 2022 from 2023-12-12T19:42:53.801643

In Part 2 of Cognitive and Behavioural Changes, Naila covers 8 papers on neuropsychiatric, social and cognitive symptoms linked to Alzheimer's disease, and their implications for diagnosis and d...

308 - Synaptic Transmission in Alzheimer's Disease: August 2022 from 2023-12-12T19:42:53.797957

To kick off our series on August papers, we will talk all about different ways that synaptic transmission may be affected in Alzheimer's disease, with 6 research papers that use either cell mode...

322 - Functional Connectivity&Imaging in Alzheimer's Disease: November 2022 from 2023-12-12T19:42:53.762296

Ellen brings you summaries of 8 abstracts from November 2022, all about functional connectivity and imaging in the context of Alzheimer's disease. There are a variety of brain regions covered in...

323 - The Immune System&Glia in Alzheimer's Disease Part 1: November 2022 from 2023-12-12T19:42:53.757968

Welcome our new host, Anelya, who covers 12 papers on the role of immune system and glia in Alzheimer’s disease. The first half of this episode will focus on potential targets for the treatment ...

328 - Functional Connectivity&Imaging in Alzheimer's Disease: January 2023 from 2023-12-12T19:42:53.741471

In today’s episode of AMiNDR, Ellen will tell you all about the functional connectivity of different networks in the brain, and changes to brain structure and volume in Alzheimer’s disease. This...

329 - Treatments Targeting Neurotransmission in Alzheimer's Disease: January 2023 from 2023-12-12T19:42:53.737140

This episode covers some papers from January 2023 on treatments focused on repairing the neurotransmitter imbalance in Alzheimer's disease. We hope you enjoy listening as Christy summarizes this...

331 - Treatments Targeting Neuroprotection in Alzheimer's Disease: February 2023 from 2023-12-12T19:42:53.716848

This short and sweet episode kicks off the February 2023 series, highlighting studies all the way from worms to humans. Anusha will take you through 9 papers that converge on targeting neuroprot...

332 - Prevention&Intervention Strategies for Alzheimer's Disease: February 2023 from 2023-12-12T19:42:53.711966

In today's episode, Naila provides you with an overview of 10 paper published in February 2023, on non-pharmacological therapies for Alzheimer's disease. You'll learn about a virtual reality int...

333 - Cognitive&Behavioural Changes in Alzheimer's Disease: February 2023 from 2023-12-12T19:42:53.706475

If you’re interested in hearing about the impact of hearing aids on quality of life in AD patients, or how having a stable life partner can slow down the progression of dementia, tune in to this...

330 - Vascular Changes in Alzheimer's Disease: January 2023 from 2023-04-11T14:54:12

Elyn's back with more insight from the field on how blood vessel health impacts brain health. Tune in for a journey through mechanisms underlying increased risk from "vascular risk factors" like...

327 - Prevention&Intervention Strategies for Alzheimer's Disease: January 2023 from 2023-03-30T18:43:02

Naila covers 11 papers from January 2023, with a focus on a variety of stimulation techniques. You'll get a smattering of new research from humans to mice to flies, and from brain imaging to com...

326 - Cognitive&Behavioural Changes in Alzheimer's Disease: January 2023 from 2023-03-28T22:39:20

We’ve got a whole variety of studies in this January 2023 episode, spanning from sensory processing, to sleep, and even to depressive symptoms. Tune in to learn more about the latest in cognitiv...

325 - Treatments Targeting Neuroprotection in Alzheimer's Disease: January 2023 from 2023-03-23T04:18:07

In this episode, we’ll be covering papers that were released in January 2023 that target neuronal and synaptic protection in Alzheimer’s Disease. If you’re interested in the preclinical testing ...

324 - Synaptic Transmission in Alzheimer's Disease: January 2023 from 2023-03-21T03:40:50

We are diving in to all things neurotransmitters and synaptic signaling to kick off the January 2023 series. You'll hear about dopamine, noradrenaline, prion proteins, a new 3D cell culture mode...

321 - Prevention&Intervention Strategies for Alzheimer's Disease: November 2022 from 2023-02-28T05:08:19

For today's episode, Naila is back to take you through 20 papers on prevention and intervention strategies in Alzheimer's. You'll be treated to the latest on mindfulness and meditation, the defa...

320 - Treatments Targeting Neuroprotection in Alzheimer's Disease: November 2022 from 2023-02-23T03:00

In this episode, Anusha guides you through 11 papers that were published in November of 2022. These papers study the efficacy of treatments targeting neuroprotection in Alzheimer's Disease model...

319 - Cognitive&Behavioural Changes in Alzheimer's Disease Part 1: November 2022 from 2023-02-21T04:00

Judy is so excited to take you through part 1 of the behavioural and cognitive changes in AD episode (part 2 will be released as a bibliography). This shorter episode features standard motor sym...

318 - Synaptic Transmission in Alzheimer's Disease: November 2022 from 2023-02-16T03:03:32

Ellen kicks off the November 2022 series with 11 papers about synaptic transmission and neurotransmitters in Alzheimer's disease. Hear about glutamate, acetylcholine, synaptic proteins, and more...

317 - Functional Connectivity&Imaging in Alzheimer's Disease: October 2022 from 2023-01-27T21:00

Today, we talk all about neuroimaging, with 7 papers that use various imaging modalities in humans, animals, and computational modeling, to study how the brain changes in Alzheimer’s disease. Tu...

316 - Treatments Targeting Neuroprotection in Alzheimer's Disease: October 2022 from 2023-01-24T04:30

Anusha brings you another episode of AMiNDR featuring literature published in October 2022. In this episode, you'll hear 12 papers that converge on the topic of treatments that target neurotoxic...

315 - Cognitive and Behavioural Changes in Alzheimer's Disease: October 2022 from 2023-01-19T04:49:35

In today's episode, there's a big focus on sleep in Alzheimer's disease, as well as other clinical and pharmacological studies that dive into the cognitive and behavioural deficits. We even have...

314 - Vascular Changes in Alzheimer's Disease: October 2022 from 2023-01-17T04:22:16

In this episode, Elyn takes you through 13 papers from October 2022 published on vascular contributions to Alzheimer disease. It's quite the journey through mechanistic mouse studies, neuroimagi...

313 - Synaptic Transmission in Alzheimer's Disease: October 2022 from 2023-01-12T02:01:27

Kick off the new year with Ellen, who tells you all about synaptic transmission in Alzheimer's disease in this episode. You'll hear about 5 papers published in October of 2022 on synaptic transm...

312 - Prevention&Intervention Strategies for Alzheimer's Disease: August 2022 from 2022-12-29T05:49:47

We have one last episode for you to wrap up 2022! In this episode, Naila will guide you through 11 papers published in August 2022, covering a range of way researchers are working on preventing ...

311 - Understanding APOE: August 2022 from 2022-12-22T06:41:38

In this month's episode of AMiNDR, Cassi recaps papers on APOE published in August 2022. Cassi just defended her dissertation where she studied immunometabolism in the context of APOE. She start...

310 - Cognitive and Behavioural Changes in Alzheimer's Disease: August 2022 from 2022-12-15T19:00:01

Today, we have papers on behavioural and cognitive changes in Alzheimer’s disease. We’ve got our usual sections such as rodent models and sleep, but we also have some new topics, including cogni...

309 - Vascular Changes in Alzheimer's Disease: August 2022 from 2022-12-13T05:53:29

After a bit of a break, Elyn is excited to be back with the latest in the field of vascular contributions to Alzheimer disease. With the current (and constant) controversy in the field about tar...

305 - Treatments Targeting Neuroprotection in Alzheimer's Disease: July 2022 from 2022-10-27T05:24:20

This is an episode all about targeting synaptic and neuronal heath in Alzheimer's disease. Anusha will cover in silico, in vitro, and in vivo studies of candidate compounds that target neuroprot...

304 - Understanding APOE: July 2022 from 2022-10-20T03:49:56

In this episode exploring the effect of allelic variation of APOE, we review abstracts from large human GWAS studies all the way down to new mouse models expressing the human ApoE proteins. Ther...

303 - Cognitive&Behavioural Changes in Alzheimer's Disease Part 1: July 2022 from 2022-10-17T21:00

Part 1 of our cognitive and behavioural changes category will focus on papers that explore behavioural and sensory processing deficits in AD. Topics range from motor impairments to visual and ol...

302 - Vascular Changes in Alzheimer's Disease: July 2022 from 2022-10-13T03:00

Elyn is back to discuss the latest research on vascular contributions to Alzheimer disease! Tune in to hear about proteomic changes with amyloid deposition in the vasculature, new therapeutic av...

301 - Synaptic Transmission in Alzheimer's Disease: July 2022 from 2022-10-12T21:28:56

We are kicking off our July 2022 series of AMiNDR with this episode and are so glad you are tuning in. If you’re interested in changes to neuronal function in AD, we’ll be covering the entire sp...

300 - Prevention and Intervention Strategies for Alzheimer's Disease: June 2022 from 2022-09-17T04:59:07

Today's episode includes 15 papers on non-pharmacological treatments and complementary therapies for AD. Naila will take you through research published in June 2022 on an array of topics includi...

299 - Cognitive Assessment in Alzheimer's Disease Part 2: June 2022 from 2022-09-15T18:41

We promised you we would be back with more on clinical assessment for Alzheimer’s disease, and here we are to deliver.  

Stick around to hear about papers published in June 2022 on validat...

295 - Cognitive and Behavioural Changes in Alzheimer's Disease: June 2022 from 2022-08-29T17:11:34

This episode contains a whole range of topics in cognitive and behavioural changes in AD! Tune in as Judy covers a variety of papers published in June 2022, spanning from from sensory processing...

294 - Cognitive Assessment in Alzheimer's Disease Part 1: June 2022 from 2022-08-26T19:00

You are here, with us, right now, about to get the updates you eagerly wait for every month in Alzheimer’s disease research. A whole episode dedicated to assessing neurocognitive domains for scr...

293 - Vascular Changes in Alzheimer's Disease: June 2022 from 2022-08-24T19:00

Ever thought there was more to Alzheimer disease than the plaques and tangles? You've come to the right place. Join Elyn for a guide through the latest research on vascular contributions to Alzh...

292 - Synaptic Transmission in Alzheimer's Disease: June 2022 from 2022-08-23T04:38:38

We are kicking off our June 2022 series of episodes with this short and sweet episode. Anusha takes a look at papers published on the subject of changes to synaptic transmission and neuronal exc...

290 - Treatments Targeting Neuroprotection in Alzheimer's Disease: May 2022 from 2022-07-29T19:00

Anusha is excited to guide you through 12 papers published in May of 2022 that all test different treatment options for Alzheimer’s disease, preclinically. She will cover topics like discovery a...

289 - Cognitive and Behavioural Changes in Alzheimer's Disease: May 2022 from 2022-07-27T19:00

In this exciting episode, Judy goes over papers published in May 2022 on the latest research involving cognitive, behavioural and clinical changes in AD. Subjects include sensory processing, mou...

288 - New Variants and Genetic Insights Part 1: May 2022 from 2022-07-25T19:00

In this episode, Joseph is back to go over papers published in May 2022 on GWASs, genetics or any other genetics-focused work. Topics include GWAS's, tool development, gene discovery, and social...

287 - Cognitive Assessment in Alzheimer's Disease: May 2022 from 2022-07-22T19:00

Welcome welcome! This episode was made for you if you are interested in geriatrics, neurology, or cognitive testing in general, as we will go through the latest publication on clinical assessmen...

286 - Synaptic Transmission in Alzheimer's Disease: May 2022 from 2022-07-20T19:00

AMiNDR is back and excited to bring you more literature on Alzheimer’s Disease. In this episode, we’ve got papers published in May of 2022 on the subject of changes to synaptic transmission and ...

285 - Prevention and Intervention Strategies for Alzheimer's Disease: March 2022 from 2022-06-10T22:00:26

In the final episode of the March 2022 series, Naila takes you through 18 papers on non-pharmacological strategies for preventing or treating Alzheimer's disease. You'll hear the latest from ani...

283 - Cognitive Assessment in Alzheimer's Disease Part 1: March 2022 from 2022-05-28T05:23:21

This is our monthly update on clinical assessment of Alzheimer’s disease, based on abstracts published in March 2022! This is the first of a 2-part series on the matter, where we bring together ...

282 - Treatments Targeting Neuroprotection in Alzheimer's Disease: March 2022 from 2022-05-26T04:31:41

Another 12 papers published in March of 2022 awaits you. This episode is all about treatments that target neuroprotection to treat AD. The papers model it by inducing cytotoxicity in the brain, ...

281 - Synaptic Transmission in Alzheimer's Disease: March 2022 from 2022-05-24T03:35:02

Ease in to our March 2022 series with 8 papers published on the subject of synaptic transmission in Alzheimer's Disease. Anusha will highlight changes to connectivity and ones caused by APP and ...

280 - Treatments Targeting Neuroprotection in Alzheimer's Disease: February 2022 from 2022-04-30T02:05:59

In February of 2022, 8 papers were published on the topic of using neuroprotective compounds as treatment for AD. Anusha will guide you through these papers exploring the entire drug discovery p...

279 - Treatments Targeting the Immune System in Alzheimer's Disease: February 2022 from 2022-04-28T04:28:40

February 2022 was full of abstracts using unique therapeutic approaches to target Alzheimer's disease. Cassi presents abstracts on both naturally-occurring and pharmaceutical compounds used to t...

278 - Risk Factors for Alzheimer's Disease Part 1: February 2022 from 2022-04-26T00:13:59

In today's episode, Naila will guide you through 19 papers from February 2022 on the prevalence and incidence of Alzheimer's disease in various study populations, social determinants of health, ...

277 - Cognitive Assessment in Alzheimer's Disease Part 2: February 2022 from 2022-04-23T02:00

Welcome back for the continuation of our segment on clinical assessment. You heard about testing specific neurocognitive domains in part 1, and here we’re back to cover abstracts that look at th...

276 - Cognitive Assessment in Alzheimer's Disease Part 1: February 2022 from 2022-04-22T23:35:54

If you wanted to detect and diagnose Alzheimer’s disease, or assess disease progression, what aspects of cognition would you focus on? In other words, what capabilities would you test to decide ...

275 - Prevention and Intervention Strategies for Alzheimer's Disease: February 2022 from 2022-04-20T21:00

This month's episode covers a range of interventions and non-pharmacological treatments that could help prevent or live with AD. Naila will take you through the various mechanisms underlying the...

274 - Vascular Contributions to Alzheimer's Disease: February 2022 from 2022-04-18T22:00

Ever wondered how amyloid deposited in cerebral vessels might affect cerebrovascular reactivity? Or how the culture time of iPSC-derived brain microvascular endothelial-like cells changes their ...

272 - Risk Factors for Alzheimer's Disease Part 1: January 2022 from 2022-03-30T22:00

In Part 1 of this 2-part episode on epidemiological studies published in January 2022, Naila will take you through 12 papers on risk and protective factors linked to Alzheimer's disease, ranging...

271 - Vascular Contributions to Alzheimer's Disease: January 2022 from 2022-03-29T07:39:49

With her first episode covering papers from 2022, Elyn is back with a lot of new and interesting findings implicating blood-brain barrier dysfunction in Alzheimer disease. Tune in to hear about ...

270 - Treatments Targeting Neuroprotection in Alzheimer's Disease: January 2022 from 2022-03-26T03:34:22

Pssst. Did you hear that 14 papers were published in January of 2022 on treatments targeting synaptic and neuronal protection in Alzheimer's disease? Anusha has you covered with papers targeting...

269 - Structural Changes in the Brain in Alzheimer's Disease: January 2022 from 2022-03-24T18:41:17

What information do grey and white matter tell us about mild cognitive impairment vs. Alzheimer's disease? Enjoy this episode in which Christy goes over study findings from 12 papers published i...

268 - Prevention and Intervention Strategies for Alzheimer's Disease: January 2022 from 2022-03-22T09:44:58

Today's episode will take you all the way from the molecular to the human level in 16 papers on non-pharmacological approaches for preventing or treating Alzheimer's disease. Naila will guide yo...

267 - Synaptic Transmission in Alzheimer's Disease: January 2022 from 2022-03-14T21:00

We start off our January 2022 series of AMiNDR with this episode highlighting 9 papers on changes to synaptic transmission in Alzheimer's Disease. In this episode, Anusha will cover topics inclu...

264 - Tau Protein Pathology in Alzheimer's Disease: December 2021 from 2022-02-28T22:00

Tickled by tau? Preoccupied with post-translational modifications? Join Kate as she covers the latest papers published in December 2021 on tau protein pathology and targeting tau as a therapeuti...

263 - Vascular Contributions to Alzheimer's Disease: December 2021 from 2022-02-24T00:20:45

Tired of the amyloid cascade hypothesis? Think there's more to AD than the plaques and tangles? You've come to the right place! Elyn is back for her final episode covering papers from 2021 on Va...

262 - Prevention and Intervention Strategies for Alzheimer's Disease: December 2021 from 2022-02-22T06:18:27

In today's episode, Naila will take you through 11 studies from December 2021 on different non-pharmacological methods for treating Alzheimer's disease. You'll hear the latest research on the im...

261 - Clinical Assessment in Alzheimer's Disease Part 2: December 2021 from 2022-02-19T21:12:12

This episode of AMiNDR is part 2 of our Clinical Assessment series. Today, you'll hear about new cognitive tests and advancements in existing tools for clinical testing. With every new study on ...

260 - Clinical Assessment in Alzheimer's Disease Part 1: December 2021 from 2022-02-18T17:00

Can smell, gaze, blinking rate, or handwriting offer a window into what happens inside the Alzheimer’s disease brain? Are there parameters we can add to our batteries for assessing cognitive dec...

259 - Changes to Synaptic Transmission in Alzheimer's Disease: December 2021 from 2022-02-17T00:00

Could changes to synaptic transmission underlie Alzheimer's disease pathology? Anusha has 8 papers to help you answer that question. These papers assess changes in humans, human models, and anim...

258 - Cognitive&Behavioural Changes in Alzheimer's Disease: December 2021 from 2022-02-15T06:30:32

To kick off this series, Ellen tells you about 17 studies published in December 2021 on how different forms of cognition, sensory processing, and psychiatric health can be affected in Alzheimer'...

257 - Risk Factors for Alzheimer's Disease: November 2021 from 2022-02-10T00:00

Naila's back with 19 epidemiological and observational studies published in November 2021. It's quite the panoply of topics - you'll hear about marital status, air pollution, metabolic syndrome,...

253 - Vascular Contributions to Alzheimer's Disease: November 2021 from 2022-01-31T17:00

Interested in a fresh perspective on the etiology of AD? Join Elyn for her monthly tour through the new research on vascular contributions to Alzheimer disease! Whether this is your niche field,...

252 - Clinical Assessment of Alzheimer's Disease: November 2021 from 2022-01-29T02:00

Welcome all researchers, students, and clinicians who are interested in learning about clinical testing for Alzheimer’s disease! This episode is dedicated to papers published back in November 20...

251 - Prevention&Interventions for Alzheimer's Disease: November 2021 from 2022-01-27T04:27

In today's episode, Naila will guide you through 10 papers that were published in November 2021 on preventing and treating Alzheimer's disease. You'll hear about snoring, caffeine consumption, t...

250 - Changes to Synaptic Transmission in Alzheimer's Disease: November 2021 from 2022-01-25T03:00

You have just entered the magical world of Alzheimer’s literature. You are about to experience 8 papers that do their best to better understand the changes in synaptic transmission in Alzheimer’...

249 - Cognitive&Behavioural Changes in Alzheimer's Disease: November 2021 from 2022-01-21T17:00

To kick off the November 2021 series, Ellen brings you 11 papers published this past November on the topic of Alzheimer's disease and dementia. Tune in to hear about research on chronic stress, ...

SPECIAL: Lessons from Grad School with Neuropsyched Magazine from 2022-01-18T01:48:33

In this special episode of AMiNDR, where we sit down with Jenn Kim and Lucy Aceves, two of the creators of the graduate student-run Neuropsyched Magazine! We talk all things graduate school and ...

247 - Risk Factors for Alzheimer's Disease Part 2: October 2021 from 2022-01-14T17:00

Naila is back for part 2, to take you through epidemiological studies on lifestyle factors and comorbidities related to Alzheimer's disease. In today's episode, you'll learn about dietary factor...

246 - Risk Factors for Alzheimer's Disease Part 1: October 2021 from 2022-01-12T17:00

In Part 1 of our episode on epidemiological studies from October 2021, Naila will cover 11 papers on demographic and socioeconomic factors related to dementia and Alzheimer's disease. You'll hea...

245 - Synaptic Transmission in Alzheimer's Disease: October 2021 from 2022-01-10T20:00

Thinking about thinking? Changes to synaptic transmission contribute to Alzheimer's disease pathology. Hear all about 10 papers published in October of 2021 exploring synaptic dysfunction in AD ...

241 - New Variants&Genetic Insights Part 1: October 2021 from 2021-12-24T17:00

Join Marcia for Part 1 of this genetics episode covering a total of 13 papers. In this one, she talks about papers from October 2021, related to transcriptomics, especially genes that are differ...

240 - Treatments Targeting Neuroprotection and Neurotransmission: October 2021 from 2021-12-22T17:00

Hello there! Just in time for the holiday season we've got quite the deal lined up for you. Two episodes for the length of one! Anusha will be guiding you through the literature of October 2021 ...

239 - Prevention&Intervention Strategies for Alzheimer's Disease: October 2021 from 2021-12-20T22:00

We've got a short and sweet episode for you today, with 7 papers from October 2021 on the intervention and prevention of AD. Tune in to hear Naila ramble on about pet therapy, update you on diet...

238 - Brain Imaging of Structural Changes in Alzheimer's Disease: October 2021 from 2021-12-17T17:00

We have 14 papers in this episode using structural magnetic resonance imaging (sMRI) in the diagnosis or prognosis of Alzheimer's Disease. Join Christy as she walks you through some deep learnin...

237 - Tau Protein Pathology in Alzheimer's Disease: October 2021 from 2021-12-16T04:24:44

Kate lets you know what's going on in the world of tau protein research in this episode of AMiNDR! Tune in to hear all about tau seeding, tau pathology, and potential therapeutic interventions f...

233 - Clinical Markers of Alzheimer's Disease: September 2021 from 2021-12-16T00:34:01.280734

You may have come across a variety of exams used to test cognitive function and assess cognitive decline, such as the Addenbrooke's Cognitive Examination, the mini mental state exam, the clock draw...

234 - Clinical Markers for Alzheimer's Disease: September 2021 from 2021-12-16T00:34:01.275867

Were you looking to learn about clinical testing for Alzheimer’s disease? This is Part 2 of our monthly episode on cognitive and clinical markers for diagnostic and prognostic purposes. Come learn ...

236 - Detecting Amyloid, Tau&New Markers in the Brain: October 2021 from 2021-12-13T18:00

To kick off our series on papers published in October 2021, we'll look at 7 papers that rely on Positron Emission Tomography (or PET) imaging to detect amyloid and tau pathology in the brain, wi...

235 - Vascular Contributions to Alzheimer's Disease: September 2021 from 2021-12-11T10:56:49

Feeling like we're beating a dead horse with the amyloid cascade hypothesis? Think there's an X-factor to Alzheimer disease that is tied to both the clinical symptoms and the plaques? Could be t...

230 - Risk Factors for Alzheimer's Disease Part 2: September 2021 from 2021-11-30T06:55:45

Back for part 2, Naila takes you through 15 papers pertaining to health conditions associated with AD and dementia. You'll hear about infections, cardiovascular and metabolic risk factors, and a...

229 - Risk Factors for Alzheimer's Disease Part 1: September 2021 from 2021-11-27T06:26:57

In today's episode, Naila takes you through 10 papers on risk factors associated with Mild Cognitive Impairment, Alzheimer's and dementia. You'll hear a little on lifestyle factors, air and nois...

228 - New Variants&Genetic Insights in Alzheimer's Disease: September 2021 from 2021-11-25T04:00

Join Glory to learn about the newest genetic variants and mechanisms that have been linked to Alzheimer's disease. In this episode, we'll cover protective and pathogenic AD variants in genes, po...

227 - Autophagy&Proteostasis in Alzheimer's Disease: September 2021 from 2021-11-23T05:14

Tune into this month's episode on the latest research on autophagy and proteostasis in Alzheimer's Disease. This includes papers on how autophagy and protein homeostasis are dysfunctional in thi...

226 - Treatments Targeting Mitochondria&Metabolism in Alzheimer's Disease: September 2021 from 2021-11-19T17:00

Let’s take a trip with Vee through the latest literature to the mitochondria and learn about oxidative stress, metabolism and related therapeutics in Alzheimer’s disease pathology. A jam packed ...

225 - Detecting Amyloid, Tau and New Markers in the Brain in Alzheimer's Disease: September 2021 from 2021-11-18T04:00

Let's take a closer look at 18 papers published in September 2021 that rely on positron emission tomography (or PET) to detect amyloid and tau pathology in the brain, within the context of Alzhe...

224 - Tau Protein Pathology in Alzheimer's Disease: September 2021 from 2021-11-16T06:00

Tired of untangling the tricky world of tau literature all on your own? Interested in the mechanisms of tau pathology, therapeutic advancements targeting tau, or both? Join Kate for another exci...

223 - Treatments Targeting Neurotransmission in Alzheimer's Disease: September 2021 from 2021-11-12T20:00

18 papers published in September of 2021 await you. What do they all have in common? They explore treatments for Alzheimer's disease that all target neurotransmission. If you're interested in re...

222 - Changes to Synaptic Transmission in Alzheimer's Disease: September 2021 from 2021-11-11T04:39:22

Are you interested in neuronal hyperexcitability, impairments in synaptic plasticity, and interactions between amyloid plaques and synaptic proteins in Alzheimer's disease pathology? You've come...

218 - Cognitive and Behavioural Changes in Alzheimer's Disease: August 2021 from 2021-10-30T03:00

In today's episode of AMiNDR, we’ll be talking about the latest work on cognitive and behavioural changes in Alzheimer's Disease, including papers on executive functioning, depression, social im...

217 - Autophagy&Proteostasis in Alzheimer's Disease: August 2021 from 2021-10-28T03:58:01

Are you familiar with protein aggregation in Alzheimer's disease, but want to learn more about the mechanisms cells use to fight back against these stubborn species? Join Kate in exploring the l...

216 - Familial Mutations, New Variants&More Genetic Insights: August 2021 from 2021-10-26T03:29:33

Buckle down and get ready for a lengthy episode on the most recently discovered familial mutations and variants related to Alzheimer's disease. With Glory as your host, we'll take a look at diff...

215 - Treatments Targeting Mitochondria&Metabolism: August 2021 from 2021-10-23T17:46:13

Join Marcia as she explores the what’s, how’s, and why’s of all things oxidative stress, mitochondrial dysfunction and metabolism in AD.  With this month’s - August 2021- papers, you’ll hear abo...

214 - Risk Factors for Alzheimer's Disease: August 2021 from 2021-10-21T00:00

Make yourself comfortable, because we cover a lot of ground in today's episode. Naila will guide you through 24 papers from August 2021, all pertaining to epidemiological studies on the risk and...

213 - Vascular Contributions to Alzheimer's Disease: August 2021 from 2021-10-18T23:00

Tired of the age-old amyloid cascade hypothesis? Think there's more to Alzheimer disease than amyloid and tau? Join Elyn in unpacking the latest literature on vascular contributions to Alzheimer...

212 - Synaptic Transmission in Alzheimer's Disease: August 2021 from 2021-10-16T04:00

Want to know more about about how the brain's different neurotransmitter systems aren't functioning properly in Alzheimer's disease and how hippocampal synaptic plasticity impairment contributes...

211 - Changes to Gene Expression in Alzheimer's Disease: August 2021 from 2021-10-14T01:00

“Changes to the expression of genes may influence the delicate balance between disease and health”. If you want to learn about how that is relevant to Alzheimer’s disease, you’ve come to the rig...

210 - Tau Protein Pathology in Alzheimer's Disease: August 2021 from 2021-10-12T02:38:23

Today, Kate will be focusing on everything tau-related in 12 papers published in August 2021, including aspects of tau pathology and exploring potential therapeutics targeting tau in Alzheimer’s...

206 - Prevention&Intervention Strategies in Alzheimer's Disease: July 2021 from 2021-09-23T00:00

Today's episode covers 18 papers on prevention and intervention strategies for Alzheimer's disease and dementia. Naila will take you through clinical trials and animal studies on cognitive train...

205 - Treatments targeting neurotransmission in Alzheimer's Disease: July 2021 from 2021-09-22T04:59:52

Journey through the entire spectrum of drug development as Anusha guides you through 19 papers that were published in July of 2021. We span research that begins with drug discovery all the way t...

204 - Clinical Markers of Alzheimer's Disease Part 2: July 2021 from 2021-09-21T03:00

In this episode, Ellen tells you about 9 papers that have developed new ways to screen for dementia. Some of these are old, tried-and-true cognitive screening tools that are given a new twist, o...

203 - Clinical Markers of Alzheimer's Disease Part 1: July 2021 from 2021-09-17T21:37:41

In the first part of this 2-parter episode, Ellen covers studies that compare and contrast different cognitive tests, or analysis techniques, for diagnosing AD at early stages, or predicting the...

202 - Tau protein pathology in Alzheimer's Disease: July 2021 from 2021-09-16T04:41:45

Kate brings you the latest research on tau pathology in Alzheimer's Disease. This includes post-translational modifications, tau aggregation and seeding, and targeting tau in treatment developme...

201 - Vascular Contributions to Alzheimer's Disease: July 2021 from 2021-09-15T04:48:20

Interested in how the 700km of blood vessels in the brain are linked to Alzheimer disease? Turns out there are a lot of common threads! In this episode, Elyn covers a series of clinical and prec...

200 - Connectivity Changes in Alzheimer's Disease: July 2021 from 2021-09-14T06:05:34

In this shorter episode, Judy covers studies on structural and functional connectivity changes in AD, as well as new methods of integrating multimodal neuroimaging data. All 9 papers were publis...

199 - Treatments targeting neuroprotection in Alzheimer's Disease: July 2021 from 2021-09-10T21:00

Animal and cell models of Alzheimer's Disease are featured in this episode that covers potential therapeutics that target neuroprotection. We have 5 papers that focus broadly on the subject and ...

194 - Treatments targeting Neurotransmitter Imbalances: June 2021 from 2021-08-19T02:00

In this episode, Anusha will guide you through 20 papers that tackle acetylcholine and glutamate imbalances in Alzheimer's Disease. These papers were published in June of 2021 and address topics...

193 - Clinical Markers of Alzheimer's Disease: June 2021 from 2021-08-18T06:39:50

In this episode, Maria will be going over 17 papers published in June 2021 on Clinical Indicators of Alzheimer's diseaes and mild cognitive impairment. Topics covered will include the use of tec...

192 - Risk Factors for Alzheimer's Disease: June 2021 from 2021-08-17T03:10:37

Naila has 23 papers for you today, that will provide you with an overview of epidemiological research published in June 2021. You'll hear about the incidence and prevalence of AD in specific pop...

191 - Detection of Amyloid, Tau and new PET targets in Alzheimer's Disease: June 2021 from 2021-08-13T21:00

Here, we'll be taking a closer look at 14 papers published in June 2021 that rely on Positron emission tomography imaging (or PET) to detect amyloid and tau pathology in the brain, within the co...

190 - Brain Connectivity Changes in Alzheimer's Disease: June 2021 from 2021-08-13T01:00

Interested in brain connectivity changes specific to Alzheimer's disease? Come join us as Judy presents 13 papers featuring fMRI, machine learning and other brain mapping techniques that explore...

189 - Vascular Contributions to Alzheimer's Disease&Treatments Targeting the Vasculature: June 2021 from 2021-08-12T04:56:49

With a shorter epsiode than usual this month, Elyn is back with an update on vascular contributions to Alzheimer disease and potential treatment avenues targeting the vasculature. Tune in for a ...

188 - APP processing&Amyloid-beta aggregation in Alzheimer's Disease: June 2021 from 2021-08-11T03:29:21

Only 14 papers published on APP processing and Amyloid-beta aggregation in the month of June, what’s going on? Well, it is still our pleasure to give you brief summaries on the matter, so if you...

187 - Prevention&Intervention Strategies for Alzheimer's Disease: June 2021 from 2021-08-10T04:43:39

In this short and sweet episode, Naila covers 12 papers from June 2021 regarding non-pharmacological strategies to prevent or intervene in dementia progression. You'll hear about a few exercise ...

181 - Clinical Markers of Alzheimer's Disease Part 2: May 2021 from 2021-07-15T04:24:04

From standard clinical testing to motor assessments such as gait performance and handwriting ability, Judy will cover 10 papers on various types of markers in Alzheimer's Disease. Tune in for ou...

180 - Clinical Markers of Alzheimer's Disease Part 1: May 2021 from 2021-07-14T05:40:56

In this episode, Maria goes over 22 papers from May 2021 on various cognitive tests for Alzheimer's disease and mild cognitive impairment. Paper topics include tests of general cognition, visual...

178 - Amyloid-Beta Pathology in Alzheimer's Disease: May 2021 from 2021-07-10T03:00

In the second part of our episodes on amyloid-beta, we focus on the ways abeta contributes to AD pathology. This ranges from its effects on the hippocampus and memory, to more mechanistic studie...

170 - Hemodynamics, Metabolic Changes&EEG in Alzheimer's Disease: May 2021 from 2021-06-30T06:07:02

From working memory tasks to mouse models, and even to lexical semantics, Judy goes over a wide range of papers that study AD diagnosis using a variety of neuroimaging techniques. Check out this...

169 - Treatments targeting Neuroprotection and Synaptic Activity in Alzheimer's Disease: May 2021 from 2021-06-29T01:00

Anusha will guide you through 21 papers in this episode that target synaptic and neuroprotection as therapeutic intervention for Alzheimer's disease. She covers 3 topics including the use of pre...

168 - Prevention and Intervention Strategies for Alzheimer's Disease: May 2021 from 2021-06-25T22:32:51

In this episode, Naila tackles 21 papers on diet, exercise, complementary therapies, cognitive training, and neurostimulation techniques. There's lots on the potential cellular mechanisms of exe...

167 - Vascular Contributions to Alzheimer Disease and Treatments Targeting the Vasculature: May 2021 from 2021-06-25T01:51:46

Elyn is back with more on all things vasculature! In this episode, she covers 14 papers that span many topics in the field of vascular contributions to Alzheimer disease - all the way from mecha...

166 - Imaging of Connectivity Changes in Alzheimer's Disease: May 2021 from 2021-06-24T03:08:54

Come join us as Judy covers all topics related to connectivity changes in Alzheimer's Disease. This episode features the latest research on both structural and functional connectivity using meth...

165 - Understanding ApoE in Alzheimer's Disease: May 2021 from 2021-06-23T07:16:36

In this episode, Courtney takes you through the papers from May 2021 on Understanding ApoE in Alzheimer's disease! We will be covering papers focused on genetic risk factors, biomarkers associat...

164 - Synaptic Transmission in Alzheimer's Disease: May 2021 from 2021-06-22T07:57:05

Ellen kicks off the May 2021 series with 20 papers all about synaptic transmission in Alzheimer's Disease. This includes topics like synaptic plasticity, neurotransmitters like acetylcholine, do...

163 - Treatments targeting Oxidative Stress&Metabolism in Alzheimer's disease: March 2021 from 2021-05-29T04:51:37

If you are interested in oxidative stress in Alzheimer’s disease, mitochondrial dysfunction, or metabolism, come hear about the ways they can be targeted for therapeutic purposes. Maybe you are ...

162 - Familial Mutations, New Variants, and More Genetic Insights in Alzheimer's Disease: March 2021 from 2021-05-28T02:00

In this short episode, Joseph goes over 9 studies published in March 2021 that include GWAS’s, ethnicity-specific genetic studies and research on familial AD genetics. Tune in to learn more!   Listen

161 - Amyloid-Beta Processing&Aggregation in Alzheimer's Disease: March 2021 from 2021-05-26T22:00

Jacques takes you on a journey through 22 papers on amyloid-beta & aggregation. Ranging from new techniques for amyloid-beta detection, APP-processing, co-pathology & Prion-like mechanisms and s...

160 - Treatments targeting the Immune System, Glia, Autophagy&Proteostasis in Alzheimer's Disease: March 2021 from 2021-05-26T03:00

In this episode, you'll hear about the latest research on targeting neuroinflammation, glial cells, autophagy and proteoastis to treat Alzheimer's Disease. This includes some studies that want t...

159 - Clinical Markers of Alzheimer's Disease Part 2: March 2021 from 2021-05-25T00:00

In Part 2 of Clinical Markers of AD, Naila will take you through 10 papers on the diagnostic and prognostic value of neuropsychiatric, sensory, motor, or a combination of symptoms. You'll learn ...

158 - Clinical Markers of Alzheimer's Disease Part 1: March 2021 from 2021-05-24T00:30:40

In part 1 of the clinical markers of AD episodes, Ellen will tell you about papers from March 2021 all about cognition. This includes papers on new cognitive tests, improving or adapting old one...

157 - Changes to Gene Expression in Alzheimer's Disease: March 2021 from 2021-05-22T00:00

Transcriptional and translational dysregulation may cause changes in cellular biology and can lead to disease. In this episode, Marcia brings you the latest research in March 2020 that focus on ...

156 - Detection of Amyloid, Tau and New PET Targets in Alzheimer's Disease: March 2021 from 2021-05-21T04:54:27

In today's episode, we'll be taking a closer look at papers published in March 2021, studying amyloid and tau PET targets in Alzheimer's Disease, as well as some new PET targets.  Topics covered...

155 - Prevention&Intervention Strategies for Alzheimer's Disease: March 2021 from 2021-05-20T04:21:27

We've got a tour de force of prevention and intervention papers for you today, covering vascular function, cognitive function, diet, exercise, neuromodulatory techniques and stem cell therapies....

154 - Role of the Immune System&Glial Cells in Alzheimer's Disease: March 2021 from 2021-05-18T23:30

In this episode, Courtney takes you through the papers from March of 2021 on the Role of Immune systems and glial cells in Alzheimer's disease pathology! We will be discussing papers related to ...

153 - Understanding Cognitive&Behavioural Changes in Alzheimer's Disease: March 2021 from 2021-05-17T22:00

Tune in as Ellen updates you on all things cognition and behaviour in Alzheimer's disease. Particularly, she'll tell you about new studies from March 2021 that shed light on the characteristics ...

152 - Vascular Contributions to Alzheimer's Disease&Treatments targeting the Vasculature: March 2021 from 2021-05-17T04:05:47

Tired of the age-old amyloid cascade hypothesis? So is Elyn! Join her in this episode unpacking papers that showed up on PubMed in March 2021 that add more evidence to the tight intertwinement o...

151 - Brain Metabolic, Hemodynamic, and Connectivity Changes in Alzheimer's Disease: March 2021 from 2021-05-15T03:41:47

In this shorter episode, Judy goes through metabolic changes, hemodynamics and functional connectivity papers on Alzheimer's disease, all published in March 2021. Aside from our favorites PET, M...

150 - Mechanisms of Synaptic Transmission in Alzheimer's Disease: March 2021 from 2021-05-14T03:00

Follow along with Glory in this episode, as we dive into papers that try to uncover the link between changes in synaptic transmission and plasticity with cognitive decline and memory loss in Alz...

149 - Epidemiology of Risk Factors for Alzheimer's Disease, Part 2: March 2021 from 2021-05-12T22:00

In part 2 of epidemiological studies from March 2021, a particularly loopy, end-of-week Naila will take you through 22 papers on comorbidities and health conditions linked to Alzheimer's disease...

148 - Epidemiology of Risk Factors for Alzheimer's Disease, Part 1: March 2021 from 2021-05-11T22:00

In part 1 of epidemiological studies from March 2021, Naila will take you through 12 papers covering prevalence and incidence rates of AD, sociodemographic factors, the potential effects of lone...

147 - Treatments targeting neuroprotection, synaptic activity&neurotransmitter release in Alzheimer's Disease: March 2021 from 2021-05-10T22:00

Anusha will be summarizing for you papers published in March of 2021 that address neuronal and synaptic health in models of Alzheimer’s disease. That’s not all! We are also going to explore the ...

146 - Understanding APOE in Alzheimer's Disease: March 2021 from 2021-05-10T04:44:53

Hooray! The first episode of our March 2021 series is here! In this episode, Courtney takes you through the papers from March 2021 on Understanding ApoE in Alzheimer's disease! We will be coveri...

145 - New Genetic Variants&Insights in Alzheimer's Disease: February 2021 from 2021-04-20T22:00

Twin studies, GWAS, TWAS, EWAS and more - In this episode, Joseph takes you through 20 papers published in February 2021 that explore novel genes or variants associated with Alzheimer’s Disease,...

144 - Cognitive&Clinical Indicators of Alzheimer's Disease, Part 2: February 2021 from 2021-04-20T04:36:54

Ellen is bringing you Part 2 of our series on cognitive & clinical indicators to diagnose AD! Make sure to check out episode 143 for Part 1! In Part 2, you'll learn about the latest research val...

143 - Cognitive&Clinical Indicators of Alzheimer's Disease, Part 1: February 2021 from 2021-04-19T03:39:29

In part 1, Naila will take you through 17 papers on characterizing different cognitive profiles of Alzheimer's disease, comparing cognitive measures to pathological biomarkers, optimizing visual...

142 - Treatments targeting Mitochondria, Oxidative Stress&Metabolism in Alzheimer's Disease: February 2021 from 2021-04-17T04:02:24

Marcia is back to bring you the latest in Alzheimer's disease treatment development! Join us as we explore the complex relationship between AD and metabolic disorders like diabetes, and some the...

141 - Prevention&Intervention Strategies for Alzheimer's Disease: February 2021 from 2021-04-15T19:00

Naila provides an overview of February 2021 papers related to preventative factors and non-pharmacological interventions for AD. You'll hear about physical activity, the ketogenic diet, transcra...

140 - Treatments targeting the Immune System, Glia, Autophagy&Proteostasis: February 2021 from 2021-04-14T19:00

Deciding what to do during your lunch break or out on a stroll? Well, look no further! Listen in on Abdullah covering the latest papers from February 2021 covering the treatments targeting glia,...

139 - Brain Metabolic, Hemodynamic, and Connectivity Changes in Alzheimer's Disease: February 2021 from 2021-04-13T19:00

Judy covers a wide range of neuroimaging modalities in the context of metabolics, hemodynamics and functional connectivity in AD. Tune in if you're a fan of fMRI, PET and EEG, or if you're just ...

138 - Vascular Contributions to Alzheimer's Disease and Treatments Targeting the Vasculature: February 2021 from 2021-04-12T22:00

Elyn is back to guide your through all of the connections between blood vessels and Alzheimer disease, from papers published in February 2021. Starting the episode off with how midlife vascular ...

137 - Amyloid-beta Toxicity in Alzheimer's Disease: February 2021 from 2021-04-12T03:47:16

In this short episode packed full of insight, Jacques navigates the realms of amyloid-beta toxicity in AD. Learn about different techniques and models used to investigate amyloid-beta toxicity, ...

136 - The Role of the Immune System&Glial Cells in Alzheimer's Disease: February 2021 from 2021-04-10T04:24:30

Courtney guides you through the latest papers on the immune system and glial cells in the context of Alzheimer's Disease. This includes papers on microglia, astrocytes, and advances in methods t...

128 - Treatments targeting Neuroprotection, Synaptic Activity, and Neurotransmitter Balance in Alzheimer's Disease: February 2021 from 2021-03-31T23:00

To kick of the February 2021 series, Anusha guides you through papers recently published that target synaptic health and  acetylcholinesterase activity to uncover pathological mechanisms that un...

127 - Amyloid-beta Aggregation and Toxicity, Part 2: January 2021 from 2021-03-17T23:00

Welcome to the baptists, the tauists, and all protein aggregation and misfolding enthusiasts from the beautiful realm of neuroscience. This episode is for you if you study amyloid-beta aggregati...

126 - Brain Metabolic, Hemodynamic and Connectivity Changes in Alzheimer's Disease: January 2021 from 2021-03-17T03:05:53

In this episode we’ll cover all things metabolism, hemodynamics and connectivity in the brain, in AD. We’ll cover 26 papers published in January 2021, that dive deeper into these research topics...

125 - Prevention and Intervention Strategies for Alzheimer's Disease: January 2021 from 2021-03-16T02:00

Join Naila for 24 papers published in January 2021 on preventive strategies and non-pharmacological interventions for treating AD. She’ll catch you up on the latest exercise interventions, the v...

124 - Treatments targeting Neurotransmitter Balance in Alzheimer's Disease: January 2021 from 2021-03-14T21:20:38

Anusha is your guide through 14 papers which target neurotransmitter balance. These papers were all published in January 2021 and focus mostly on targeting acetylcholinesterase activity with a s...

123 - Advances in Cognitive&Neuropsychiatric Testing for Alzheimer's Disease Diagnosis: January 2021 from 2021-03-12T23:00

In this episode, Maria covers papers from January 2021 exploring cognitive and neuropsychiatric assessments that can be used to evaluate early AD or progression to AD.  The studies look at tests...

122 - The Role of Immune Systems&Glial Cells in Alzheimer's Disease: January 2021 from 2021-03-12T03:15:41

In this episode, Courtney takes you through the papers from 2021 on the role of Immune systems and glial cells in Alzheimer's disease pathology. The papers relate to neuroimaging, astrocytes, mi...

121 - Amyloid-beta Aggregation&Toxicity, Part 1: January 2021 from 2021-03-11T00:03:35

In this episode, the first of a two-part mini series, Jacques runs through papers from January 2021 on amyloid-beta oligomers in aggregation and therapeutics strategies to target them. Tune in t...

120 - New Genetic Variants in Alzheimer's Disease: January 2021 from 2021-03-10T02:00

The rapidly evolving field of Alzheimer’s research is always discovering new genes, variants or even pathways that are associated with this disease. In this episode, Joseph goes over 14 studies ...

111 - Mechanisms of Synaptic Transmission in Alzheimer's Disease: January 2021 from 2021-02-26T22:00

In this episode, Glory will take you through the papers published on alterations to synaptic transmission and structure in Alzheimer's disease from January 2021. Tune in for all things synaptic ...

110 - APP Processing in Alzheimer's Disease: January 2021 from 2021-02-26T04:00

In this episode, Jacques covers papers from January 2021 on the mechanisms of APP processing in Alzheimer's disease and strategies to alter amyloid-beta production. Learn something new as we exp...

109 - Cerebrovascular Changes&Treatments Targeting the Vasculature in Alzheimer's Disease: January 2021 from 2021-02-25T03:51:20

Elyn is back with more on vascular contributions to Alzheimer disease. Tune in to hear about clinical studies connecting the vasculature to the AD pathology, mechanistic studies about amyloid cl...

108 - Risk Factors for Alzheimer's Disease, Epidemiological studies: January 2021 from 2021-02-24T03:21:42

In this episode on epidemiological studies published in January 2021, Naila will take you through a range of risk factors of AD, including cardiovascular disease, diabetes, other comorbidities, ...

107 - Understanding APOE in Alzheimer's Disease: January 2021 from 2021-02-23T05:15:17

In this episode, Courtney will take you through the papers published on ApoE in Alzheimer's disease from January 2021. The topics covered include the role of ApoE on cognitive function, the impa...

106 - Treatments targeting neuronal&synaptic protection in Alzheimer's Disease: January 2021 from 2021-02-21T23:57:16

In the first episode of our January 2021 series, Anusha will be guiding you through papers that traverse topics within neuroprotection in AD models, including therapies that target A-beta toxici...

104 - Brain Imaging of Metabolic Changes and Hemodynamics in Alzheimer's Disease: September 2020 from 2021-01-29T06:00

This shorter episode on metabolic changes and hemodynamics covers a wide range of neuroimaging techniques, including FDG PET, MRI and CT. Judy will discuss the applications of these modalities i...

103 - Mechanisms underlying Risk Factors for Alzheimer's Disease: September 2020 from 2021-01-29T01:00

This episode covers recent papers that explore the underlying mechanisms of both protective and risk factors of Alzheimer’s disease. You’ll hear a little about how education, exercise and diet m...

102 - Cognitive or Clinical Indicators of Alzheimer's Disease Part 1: September 2020 from 2021-01-27T10:40

This episode, hosted by Naila, covers papers published in September 2020 that use cognitive testing as a diagnostic tool. These studies vary from validating and comparing existing tests, to refi...

101 - Treatments targeting tau protein in Alzheimer's Disease: September 2020 from 2021-01-27T00:39:01

In this episode, Marcia will cover papers published in Sept 2020 on treatment development for AD with special focus on the tau protein. She discusses tau in its role as a microtubule-associated ...

100 - Refining&Repurposing Treatments for Alzheimer's Disease: September 2020 from 2021-01-25T04:00

Can you believe this is our 100th episode??? It has been a little over 6 months since our official launch and we are now running full steam, thanks to a hardworking team. Cheers to the members o...

99 - Tau Protein Pathology in Alzheimer's Disease: September 2020 from 2021-01-24T21:00

Alyssa will cover tau protein expression, aggregation, and pathology in Alzheimer’s Disease from studies published in Sept 2020. This episode will dive into papers that examine genetic mutations...

98 - Cerebrovascular changes in Alzheimer's Disease Part 2: September 2020 from 2021-01-22T07:00

In this episode, Elyn caps off the papers on Cerebrovascular Changes in AD from September 2020. There’s mounting evidence for a significant overlap between vascular disease and brain health, and...

97 - Brain Imaging of Structural Changes&Connectivity in Alzheimer's Disease, Part 2: September 2020 from 2021-01-22T04:45

In part 2 of this series, Bhumika continues the deep dive into imaging papers from September 2020 focusing on structural changes and connectivity of the brain, and subsequent white matter change...

96 - Changes to RNA, Transcription, and Translation in Alzheimer's Disease: September 2020 from 2021-01-20T02:00

In today's episode, Glory updates you on the latest studies from September 2020 on changes to RNA, transcription, and translation mechanisms that may contribute to Alzheimer's disease pathology....

95 - Detecting Amyloid&Tau in Alzheimer's Disease: September 2020 from 2021-01-18T01:30

In this half-hour episode, Judy goes through September 2020 papers that look at diagnosing or characterizing Alzheimer's disease based on the detection of the proteins amyloid and tau in the bra...

94 - Brain Imaging of Structural Changes&Connectivity in Alzheimer's Disease, Part 1: September 2020 from 2021-01-15T05:00

Bhumika updates you on the latest papers on brain imaging of structural changes and connectivity in AD! This includes MRI and PET imaging to characterize or diagnosis this disease, as well as ne...

93 - Inflammation, Glial Cells&TREM2 in Alzheimer's Disease, Part 2: September 2020 from 2021-01-15T02:00

Courtney is back with Part 2 of Inflammation, Glial Cells and TREM2 papers published in September of 2020! If you haven't already, check out Part 1 in episode #91. In this exciting sequel, she d...

92 - Fluid Biomarkers for Alzheimer's Disease Part 2: September 2020 from 2021-01-13T01:00

Elyn is back with more on fluid biomarkers for Alzheimer’s Disease from September 2020 papers. Here, she covers new candidate biomarkers including panels of lipids, soluble TREM2, and methylatio...

91 - Inflammation, Glial Cells&TREM2 in Alzheimer's Disease, Part 1: September 2020 from 2021-01-11T06:35

Courtney updates you on all the new publications from September 2020 about inflammation, glial cells, and TREM2, in the context of Alzheimer's disease. There were a lot of papers on these topics...

85 - Fluid Biomarkers for Alzheimer's Disease Part 1: September 2020 from 2020-12-23T04:00

Interested in the mission to accurately diagnose Alzheimer’s disease with a blood test? This episode is perfect for you. In this two-part episode on Fluid Biomarkers in AD from September 2020 pa...

84 - APP processing and amyloid-beta aggregation in Alzheimer's Disease: September 2020 from 2020-12-22T20:00

In this episode, Jacques will tell you about new peer-reviewed publications from September 2020 on mechanisms of APP processing and protein aggregation in the context of Alzheimer's disease. Thi...

83 - Treatments targeting amyloid-beta aggregation and more in Alzheimer's Disease: September 2020 from 2020-12-21T07:00

In this episode, Marcia covers papers published in September 2020 that focus on the latest in novel drug development in AD. We especially talk about papers targeting amyloid-beta aggregation, BA...

82 - Metabolism&Mitochondrial Dysfunction in Alzheimer's Disease: September 2020 from 2020-12-21T05:23:21

Is your research on diet and nutrition and Alzheimer’s disease? Or maybe you are diving deeper into the role of carbs and fat metabolism, and are interested in mitochondrial function in neurodeg...

81 - Cerebrovascular changes in Alzheimer's Disease Part 1: September 2020 from 2020-12-20T20:55:08

Elyn is back to cover the latest findings relating to the cerebrovasculature in Alzheimer disease! In this two part episode covering papers from September 2020, you’ll hear about how aging and s...

80 - Understanding ApoE in Alzheimer's Disease: September 2020 from 2020-12-18T04:13:41

In this episode, Courtney will update you on papers published in September 2020 on the Disease Mechanisms of ApoE. You will hear about cognitive impacts of ApoE, ethnic variability in ApoE, Neur...

79- Treatments Targeting Oxidative Stress, Metabolism,&Behaviour in Alzheimer's Disease: September 2020 from 2020-12-18T01:37:07

If you can’t quite decide which episode to listen to, maybe give this one a try. We’re covering preclinical models of AD as it pertains to mitochondria, autophagy, metabolism, behaviour, and muc...

78 - Multi-Targeted Treatment Approaches for Alzheimer's Disease Part 2 + Gene Therapy: September 2020 from 2020-12-13T23:00

This episode is the second half of a two part series covering papers published in September 2020 on treatment approaches with multiple targets for Alzheimer’s disease. For part 1 of this series,...

77 - Oxidative Stress, Autophagy and the Gut Microbiome in Alzheimer's Disease: September 2020 from 2020-12-11T04:00

You'll hear about how mechanisms of oxidative stress, autophagy and the gut microbiome may contribute to AD pathology, as Abdullah updates you on the new papers from September 2020 on these topi...

76 - The Genetic Landscape of Sex Differences and More in Alzheimer's Disease: September 2020 from 2020-12-10T20:23:27

In this episode, Judy goes over papers published in September 2020 that focus on sex differences in Alzheimer’s disease. We also cover a few papers that did not quite fit into our other genetics...

70 - Risk Factors in Alzheimer's Disease Part 1: September 2020 from 2020-11-30T05:37:23

In the first of 3 episodes on AD risk factors for September 2020, Naila covers some of the most studied (arguably) modifiable risk factors, including diet, exercise and sleep. You'll also hear a...

69 - Treatments Targeting Synaptic Transmission in Alzheimer's Disease: September 2020 from 2020-11-29T23:46:09

Are you invested in the role of neurotransmission in Alzheimer’s disease? Well then buckle in because in this episode, Anusha will go over the latest and greatest compounds that target disease s...

SPECIAL: On Scicomm&Podcasting, with BrainBuzz! from 2020-11-28T08:50:06

Sarah and Elyn are joined by Kyle and Drake from BrainBuzz Podcast to share our journey, growth, and challenges with starting a podcast for science communication in Psychology for them, and Neur...

67 - More on Disease Mechanisms in Alzheimer's Disease: August 2020 from 2020-11-27T07:00

In this episode, Elyn takes you through a very diverse set of papers on Alzheimer’s disease mechanisms - catching all of the papers that didn’t slot nicely into other episodes. The topics span a...

66- Tau and Other Protein-Related Pathology: Alzheimer's Disease August 2020 from 2020-11-27T03:25:16

Today’s episode is on protein expression, aggregation, misfolding and pathology, with an emphasis on tau pathology in Alzheimer’s Disease and we are rounding off the papers published in August 2...

65 - GWAS, Transcriptomics,&New Tools for Genetic Research: Alzheimer’s Disease August 2020 from 2020-11-25T02:25:15

Naila is back to round off our risk factors section with an episode on genome-wide association studies, transcriptomic research, combining genetics and neuroimaging data, and new tools to make a...

64 - Cerebrovascular Changes : Alzheimer's Disease August 2020 from 2020-11-23T07:00

With over 700km of blood vessels in the brain, it’s no surprise that brain and vascular health are closely related. In this episode, Elyn takes you through papers published in August 2020 on cer...

63 - More on Diagnostic Tools: Alzheimer's Disease August 2020 from 2020-11-23T02:00

Today’s episode is all about Diagnostic Tools and Imaging papers published in August 2020. As you will soon see, these papers explore a wide range of topics including potential biomarkers of AD,...

62 - Novel Drug Development-Part 3: Alzheimer's Disease June 2020 from 2020-11-22T18:00

n this episode, Alex will be covering papers published in August 2020 within the category of novel drug development, that focus on multi-targeted approaches to Alzheimer’s disease treatment, and...

61 - More on Biomarkers: Alzheimer's Disease August 2020 from 2020-11-20T07:00

Naila covers a wide variety of biomarkers and topics from papers published in August 2020 on Alzheimer's disease: identifying biomarkers of cognition and memory in cognitively unimpaired older a...

60 - Novel Drug Development Part 2 : Alzheimer's Disease August 2020 from 2020-11-20T04:34:13

In this episode, Marcia talks about papers published in August 2020 within the novel drug development category that focus on targeting tau, the cholinergic system, mitochondria, metabolism and t...

59 - Detecting Amyloid&Tau in the Brain Part 2: Alzheimer's Disease August 2020 from 2020-11-19T18:49:31

Judy covers the second half of papers released in August 2020 on amyloid or tau protein detection in the brain. This selection features mouse models, machine learning, mass spectrometry and othe...

58 - Blood Biomarkers: Alzheimer's Disease August 2020 from 2020-11-18T07:55

Today we have another episode focused on the latest findings in Alzheimer’s disease blood biomarkers research, where Elyn covers abstracts from papers published in August 2020. These papers were...

57 - Metabolism, Mitochondrial (Dys)function, Oxidative Stress, Autophagy,&Gut Microbiome: Alzheimer's Disease August 2020 from 2020-11-18T06:58:57

Feeling PERK-y? An eclectic assortment of papers that address Alzheimer’s disease mechanisms in various ways awaits you in this episode. Anusha Kamesh will be guiding your journey through papers...

56 - Novel Drug Development Part 1: Alzheimer's Disease August 2020 from 2020-11-18T03:35:19

Marcia will tell you about papers published in August 2020 within the Novel drug development category that focus on all things Amyloid-beta. She will cover research focussed on targeting Amyloid...

55 - Refining&Repurposing Treatments: Alzheimer's Disease August 2020 from 2020-11-16T10:31:29

We may not have a disease-modifying agent for Alzheimer’s disease yet, but there are several approved medications that can help slow down the progression of the disease. Can we improve these med...

54 - CSF Biomarkers: Alzheimer's Disease August 2020 from 2020-11-16T03:00

In this episode, Alex covers the latest research involving CSF biomarkers as a critical diagnostic tool in Alzheimer’s Disease identification and treatment. You’ll hear about some of the more ty...

53 - Understanding ApoE: Alzheimer's Disease August 2020 from 2020-11-16T01:00

In this episode, Courtney will update you on papers published in August 2020 on the genetic landscapes of ApoE. You will hear about models of ApoE, ethnic variability in ApoE, clinical implicati...

SPECIAL: ONE YEAR WITH AMINDR! from 2020-11-15T05:08:06

What role does social media play in academia and science communication nowadays? How can we keep our biases from interfering with fair reporting and objective coverage? Do we need to revise our ...

51 - Cognitive Testing for Diagnosis: Alzheimer's Disease August 2020 from 2020-11-13T05:00

Ellen tells you about the latest papers on cognitive testing for AD and mild cognitive impairment! This includes papers that delve deeper into how cognition is affected in AD and other disorders...

50 - Amyloid-beta Aggregation: Alzheimer's Disease August 2020 from 2020-11-13T04:00

Listen to Jacques as he recites tongue-twisters and updates you on the latest papers on amyloid-beta aggregation and toxicity in AD from August, 2020! We hope you like the episode, and if you're...

49 - Epigenetics, Specific Molecular Pathways&Genetic Models: Alzheimer's Disease August 2020 from 2020-11-13T03:01:42

The genetic landscape of Alzheimer's disease can be overwhelmingly broad. In this episode, Joseph is back to tell you about peer-reviewed research dealing with epigenetics, non-APOE related gene...

48 - Preclinical Testing Part 3: Alzheimer's Disease August 2020 from 2020-11-11T07:09:09

Join Anusha as she dives into papers published from August of 2020 that uncovers the effects of potential therapeutics in animal models for Alzheimer's Disease. In the first section, she covers ...

47 - APP processing: Alzheimer's Disease August 2020 from 2020-11-11T04:30

In this episode, Jacques updates you on the newest papers related to amyloid precursor protein processing in AD! You'll hear about the gamma secretase complex, the influence of accessory protein...

36 - Synaptic Transmission&Sex Differences: Alzheimer's Disease August 2020 from 2020-10-29T01:06:49

Anusha is here to tell you about papers published in August 2020 on a range of topics in synaptic transmission, including changes to cholinergic signalling, glutamate signalling, synaptic plasti...

35 - Risk Factors for AD Part 1: Alzheimer's Disease August 2020 from 2020-10-25T23:59:27

Naila kicks off the August 2020 series of AMiNDR! This is part 1 of 3 of our episodes covering papers from this past August on risk factors for Alzheimer's disease. This includes the latest rese...

34 - Detecting Amyloid&Tau in the brain: Alzheimer's Disease June 2020 from 2020-10-19T02:43:14

Having trouble keeping up with the literature in Alzheimer's Disease? We are here to help!  

Ellen tells you about the papers on amyloid and tau detection in the brain, from June 2020! Thi...

33 - More on Biomarkers in Alzheimer's Disease June 2020 from 2020-10-18T06:54:26

Having trouble keeping up with the literature in Alzheimer's Disease? We are here to help!  

In this episode, Sarah covers a wide array of papers on biomarkers in AD! You may have listened...

32 - CSF&Mixed Biomarkers: Alzheimer's Disease June 2020 from 2020-10-17T11:08:43

Having trouble keeping up with the literature in Alzheimer's Disease? We are here to help!  

Elyn is back to cover other fluid biomarkers found in the CSF in AD, as well as biomarkers foun...

31 - Blood Biomarkers: Alzheimer's Disease June 2020 from 2020-10-12T04:11:09

Having trouble keeping up with the literature in Alzheimer's Disease? We are here to help!  

Elyn tells you  about papers on blood biomarkers for AD in this episode of AMiNDR! This include...

28 - Imaging Tools for Diagnosis Part 1: Alzheimer's Disease June 2020 from 2020-09-27T23:04:12

Having trouble keeping up with the literature in Alzheimer's Disease? We are here to help!  

Bhumika tells you all about the new papers on imaging tools for AD from June 2020! You'll hear ...

27 - Novel Drug Development - Part 4: Alzheimer's Disease June 2020 from 2020-09-25T05:40:45

Having trouble keeping up with the literature in Alzheimer's Disease? We are here to help!  

Joseph tells you about more papers on drugs in development from June 2020.   These studies enco...

26 - Refining and Repurposing Treatments: Alzheimer's Disease June 2020 from 2020-09-21T03:17:10

Having trouble keeping up with the literature in Alzheimer's Disease? We are here to help!  

In this episode, Sarah updates you on the papers from June 2020 that aim to refine or repurpose...

Novel Drug Development-Part 3: Alzheimer's Disease June 2020 from 2020-09-18T07:58:59

Having trouble keeping up with the literature in Alzheimer's Disease? We are here to help!  

Joseph tells you about more papers on drugs in development from June 2020.   These studies enco...

Novel Drug Development-Part 2: Alzheimer's Disease June 2020 from 2020-09-13T11:09:06

Having trouble keeping up with the literature in Alzheimer's Disease? We are here to help!  

Ellen tells you about more papers on drugs in development from June 2020.   These studies encom...

Genetic Landscape Part 2: Alzheimer's Disease June 2020 from 2020-08-31T10:01:50

Having trouble keeping up with the literature in Alzheimer's Disease? We are here to help! 

This episode is the second of two parts on the genetic landscape of AD! Here, Marcia will tell y...

Genetic Landscape Part 1: Alzheimer's Disease June 2020 from 2020-08-28T18:15:40

Having trouble keeping up with the literature in Alzheimer's Disease? We are here to help! This episode is the first of two parts on the genetic landscape of AD! Here, Marcia will tell you about...

Cerebrovascular Changes&Unclassified Disease Mechanisms: Alzheimer's Disease June 2020 from 2020-08-24T04:11:08

Having trouble keeping up with the literature in Alzheimer's Disease? We are here to help!

 Elyn will tell you all about papers from June 2020 on cerebrovascular changes and unclas...

Non-Pharmacological Treatment Approaches: Alzheimer's Disease June 2020 from 2020-08-22T06:12:50

Having trouble keeping up with the literature in Alzheimer's Disease? We are here to help!

 In this episode, Naila will tell you about topics including intermittent fasting, musica...

Metabolism, Mitochondrial (Dys)function, Oxidative Stress, Autophagy,&Gut Microbiome: Alzheimer's Disease June 2020 from 2020-08-20T06:33:08

Having trouble keeping up with the literature in Alzheimer's Disease? We are here to help!

In this episode, Anusha combines different topics pertaining to disease mechanisms in Alzheimer's...

Tau&Other Protein Related Pathologies: Alzheimer's Disease June 2020 from 2020-08-19T08:43:27

Having trouble keeping up with the literature in Alzheimer's Disease? We are here to help!

In this episode, Naila goes over the papers from June 2020 on Tau aggregation & phosphorylation a...

APP Processing&Amyloid-beta aggregation: Alzheimer's Disease June 2020 from 2020-08-18T10:24:29

Having trouble keeping up with the literature in Alzheimer's Disease? We are here to help!

In this episode, Sarah gives an overview on the papers on APP processing, then presents the lates...

Cognitive/Behavioural Testing&Unclassified Detection Methods: Alzheimer's Disease June 2020 from 2020-08-12T04:25:10

Having trouble keeping up with the literature in Alzheimer's Disease? We are here to help!

In this episode, Ellen starts by updating you on the latest papers on cognitive and behav...

Cognitive Changes&Synaptic Transmission: Alzheimer's Disease June 2020 from 2020-07-28T23:20:59

Having trouble keeping up with the literature in Alzheimer's Disease? We are here to help!  

In this episode, we cover the papers published in June 2020 about cognitive changes and synapti...

Treatment Development in Alzheimer's Disease-February 2020 - Part 2 from 2020-07-20T22:21:23

To receive the list of papers covered (with time-stamps), please subscribe to our mailing list. You can do so by filling this form: 

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Treatment Development in Alzheimer's Disease-February 2020- Part 1 from 2020-07-17T08:28:29

To receive the list of papers covered (with time-stamps), please subscribe to our mailing list. You can do so by filling this form: 

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Genetics, Risk Factors&New diagnostic tools_AD_Papers published in February 2020 from 2020-06-29T07:02:12

To receive the list of papers covered (with time-stamps), please subscribe to our mailing list. You can do so by filling this form: 

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Papers published on Alzheimer's disease in February 2020: Methods&Models from 2020-06-16T01:47:07

About the bibliography:

To receive the list of papers covered (with time-stamps), please subscribe to our mailing list. You can do so by filling this form:   https...