Ageing, metabolic acidosis&cardio-metabolic disease: Exploring the correlations - a podcast by Bio-Practica Nutraceuticals

Professor Lynda Frassetto is a Professor Emeritus of Medicine in the Division of Nephrology at the University of California, San Francisco. She teaches and supervises both inpatient and outpatient nephrology at the University and the Veteran’s Administration hospitals.

Professor Frassetto grew up in the greater New York metropolitan area and attended university and medical school in Connecticut. She trained as a nephrologist at UCSF however and was in private practice in San Francisco before commencing her research career approximately 20 years ago.

Professor Frassetto has a particular interest in the pathophysiological effects of dietary acid load and chronic metabolic acidosis on the body. Lynda is a world renown expert in this field and has published more than 100 papers on regulation of acid-base balance in healthy and ageing people; on dietary influences that affect acid-base balance; and on the role of acidosis on disease risk and ageing.

In addition to research, Dr Frassetto is the director of the Clinical Research Centre at UCSF’s Clinical and Translational Science Institute. For the last several years, she has also been participating in and teaching programs that teach UC students and faculty better communication and behavioural stress modification techniques.

1. Discuss the relationship between diet, physiological acid-base balance, and vascular health – including the impact of chronic metabolic acidosis on nitric oxide (NO) production.

2. Explore how kidney function correlates to regulation of physiological acid-base balance, and why diabetic patients are especially at risk of chronic metabolic acidosis.

3. Review evidence on how an alkaline diet can support optimal cardio-metabolic health.