Twisting the Dragon's Tail - a podcast by Center for Advanced Studies LMU

from 2018-08-16T16:10:01

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Centromeres can be used as a model for epigenetic regulation in normal and diseased states. Here the research focus is especially on non-canonical histone variants such as Centromer Protein A (CENP-A). In recent years, observations were made by the group led by Yamini Dalal, which succeeded in linking CENP-A and long non-coding RNAs (lncRNAs) originating from human centromeres to the maintenance of chromatin structure at the centromere, and dysregulation of chromatin structure in human tumors.|
Yamini Dalal is Researcher at the Laboratory of Gordon L. Hager (Receptor Biology and Gene Expression) of the National Cancer Institute in Bethesda, USA. She was a CAS Research Fellow from May to August 2017.

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