EMCrit Podcast 29 – Procedural Sedation, Part II - a podcast by Scott D. Weingart, MD FCCM

It seems the government and other specialties are trying hard to make sedation as difficult as possible in the ED. We must persevere to provide the best procedural sedation to allow maximal comfort and safety for our patients. This continues the discussion started in Part I, where we discussed etomidate, ketamine, and versed/fentanyl. In this podcast, I discuss propofol, ketofol, and dexmedetomidine.



the emcrit procedural sedation chapter has tons of references for all of this

Propofol

great propofol articles:

Ann Emerg Med 2008;52:392-398

Ann Emerg Med. 2007;50:182-187

Start with fentanyl 1-1.5 mcg/kg



Then give propofol 0.5-1 mg/kg



may need additional injections of 0.5 mg/kg



When patient is where you want them, begin the procedure



May need to give additional 20-30 mgs if the patient becomes too light



Burns on injection, you can precede with 20-40 mg of lidocaine to numb the vessels

Ketofol

read more here: (Ann Emerg Med. 2007;49:23-30)



1:1 mix of ketamine and propofol



In 20 ml syringe, place 10 ml of propofol (10 mg/ml)



And 10 ml of ketamine at a concentration of 10 mg/ml



Note: your ketamine may come in a different concentration, if so dilute down to 10 ml of 10 mg/ml



Shake like a martini

Dexmedetomidine

Precede with fentanyl 1 mcg/kg



Start with 0.5-1 mcg/kg over 10 minutes for loading dose



then use an infusion 0f 0.2-1 mcg/kg/hr



Beware in the bradycardic, hypotensive or patients with heart blocks



May need to supplement with 1-2 mg of midazolam

Procedural Sedation Checklist

here it is



Stay tuned for part III coming to you some time in the future.

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