Podcasts by Endpoints

Brooke Eby: Spreading ALS Awareness Through TikTok from 2023-03-16T18:32:07

Normally, you’d expect the subject matter of the videos you see while scrolling through TikTok to be light – funny skits, cute animals, dances, maybe a recipe or two. However, when one of Brooke...

Endpoints Shorts: Dr. Nadia Sethi on Biogen's Tofersen Trial for Presymptomatic Carriers from 2023-03-10T18:08:17

Welcome to the latest episode of Endpoints Shorts. In these bite-size podcasts, we’ll be tackling important scientific concepts for people interested in ALS research, current clinical trials, an...

Copper Complexes: Dr. Fernando Vieira on ALS TDI's Promising Potential ALS Treatment from 2023-03-03T16:20:32

ALS TDI’s primary mission is to discover treatments for everyone with ALS. Every day, our scientists are testing drugs to find the next compound with the potential to make it to clinical trials ...

Endpoints Shorts: Dr. Nadia Sethi on Ionis' FUS ASO Trial from 2023-02-28T17:59:19

Today we have the first installment of a new series we’re calling Endpoints Shorts. In these bite-size episodes, we’ll be tackling important scientific concepts for people interested in ALS rese...

Google’s Project Relate: Using Machine Learning to Help People with ALS from 2023-02-17T21:51:58

Project Relate is an app for Android phones and tablets that aims to use the power of voice recognition technology to help people with dysarthria, or difficulty speaking, in their day-to-day liv...

Dr. Silvia Pozzi on the State of Antibody Therapies for ALS from 2022-09-06T20:28:15

Antibodies are an essential part of our bodies’ defenses against diseases. They are specialized proteins that attack and kill foreign invaders like infectious bacteria and viruses.

Antibo...

Ajay Sampat: A Young Neurologist Discusses Life After ALS Diagnosis from 2022-07-28T19:22:45

ALS can happen to anyone. Although many outside of the ALS community often think of it as a disease that affects older people, onset can occur at any age, in any person, for reasons that are not...

Prime C: NeuroSense on their ALS Treatment from 2022-06-28T20:41:13

Celecoxib is a non-steroidal anti-inflammatory drug, or NSAID. Ciprofloxacin is an antibiotic that is used to treat a number of bacterial infections. The former has been trialed unsuccessfully i...

Ric Starry and Kevin Porter: 20 Years of the Tri-State Trek from 2022-05-13T13:40:47

20 years. More than 5000 miles, give or take. Thousands of riders. Countless hugs, tears, and cheers from the side of the road. And, if everything goes according to plan, $10 million raised for ...

José Fajardo on Participating in a Clinical Trial from 2022-04-15T18:24

There are currently no effective treatments available for ALS. Because of this many people living with ALS turn to Clinical Trials, both to get a chance to receive a potentially beneficial treat...

Coya Therapeutics: Treg Therapy in ALS from 2022-03-01T22:23:49

Regulatory T cells, also known as Tregs, are specialized cells that are part of the immune system. As the name implies, they help regulate the body’s immune natural immune response, among ...

Sally Stewart of the Denver Wine Merchant: Staying Involved with Her Passion in the Face of ALS from 2022-01-12T19:56

Sally Stewart knows wine. It’s the focus of her career, and her great passion. As a sommelier, she’s worked in great restaurants in places like Portland, Oregon, Telluride, Colorado,...

Project Euphonia: ALS TDI Works with Google to Help People with ALS Communicate from 2022-01-06T18:12:10

In 2018, ALS TDI began working a big collaboration with a partner you’ve probably heard of – Google.

At the time, Google was looking to put their artificial intelligence ...

Dr. Kyle Denton: Induced Pluripotent Stem Cells in ALS Research from 2021-12-16T19:17:13

One of our most powerful new tools in recent years for in vitro experiments are something called induced pluripotent stem cells, or iPSCs. iPSCs are created with a technique that allows scientis...

Carol Hamilton: How ALS TDI Works to Help Veterans with ALS from 2021-11-16T17:41:10

Much of what causes the 90% of Amytrophic Lateral Sclerosis (ALS) cases that occur sporadically remains a mystery. However, one risk factor that is supported by a large body of evidence is servi...

Tavares Speer: Spreading ALS Awareness on Social Media from 2021-11-08T18:36:21

When it’s used right, social media can be a powerful tool to spread awareness.

Before Tavares Speers was diagnosed with ALS, he already had a big social media following. His tens of...

Steve Cochlan and the ALS Family of Faith from 2021-11-01T19:54:13

After an ALS diagnosis, it can be hard to know where to turn. There are doctors and clinics that offer medical support, and services organizations that can help with getting equipment and things...

ALS TDI: The Drug Discovery Engine for ALS from 2021-10-25T19:13:56

Recently, ALS TDI took an opportunity to reintroduce ourselves. If you follow us on social media, read our emails, or check our website you may have noticed that we have a new way of describing ...

I'm Dying to Tell You: Lorri Carey on Living – and Podcasting – with ALS from 2021-09-17T17:31

If you aren’t already, you should be tuning in to I’m Dying to Tell You. It’s a podcast about inspiration, full of compelling interviews with people who have face...

What is a Biomarker? from 2021-09-08T16:49:56

Biomarkers are an important part of medical research and drug development. A biomarker is a broad term that describes some sort of measurable property of the body, especially one that can tell u...

MERIDIAN: Apellis Discusses their Phase 2 ALS Trial from 2021-08-10T18:21

The Complement system is an intriguing potential pathway for treating ALS. It’s an essential part of the immune system – and many researchers believe its dysregulation could play a r...

Lou Gehrig Day: Celebrating a Legend and Raising ALS Awareness from 2021-05-14T17:38

For years, Lou Gehrig has been recognized as both a face of ALS and a legend of Baseball. But, until now, he did not have an official day dedicated to him by the MLB, unlike some of his fellow l...

Braingate: Helping People with ALS Control Devices with their Minds from 2021-02-26T14:19:49

Today on Endpoints, we’re joined by Dr. Leigh Hochberg. He's the the Director of the Center for Neurotechnology and Neurorecovery at Mass General Hospital’s Department of Neurology a...

Lisa Cross Bonahoom: Fighting ALS for Herself and Her Family from 2020-12-29T18:22

Today we’re joined by Lisa Cross Bonahoom. Lisa is a teacher, singer, actor, director, choreographer, and dancer who was diagnosed with ALS about three years ago. She brings us a story of ...

Neurofilament Light Chain: A Potential ALS Biomarker? from 2020-12-29T16:35

Biomarkers are an important part of medical research and drug development. A biomarker is a broad term that describes some sort of measurable property of the body, especially one that can tell u...

Daniel Barvin: Working to Create a Future Without Familial ALS from 2020-12-03T21:30

Finding out a loved one has ALS can be hard enough. But for people whose family members test positive for one of the genetic mutations behind familial ALS, it can bring a whole other set of issu...

CHAMPION-ALS: Alexion Discusses their Phase 3 ALS Trial from 2020-09-29T17:34:02

Today, we’re happy to be joined by representatives from one of our partners in the industry, Alexion – a biotech specializing in rare diseases – to talk about the company and it’s upcoming CHAMPION...

Joe Lynch and Larry Cepuran: Living with ALS and Supporting ALS TDI from 2020-09-01T20:46:13

Joe Lynch hosts a podcast called “The Logistics of Logistics.” Normally this show covers topics about the logistics and supply chain industries. But recently Joe decided to switch up...

Steve Saling: 10 Years of the ALS Residence from 2020-08-13T14:11

10 years ago, today – August 13, 2010 – the doors of the Steve Saling ALS Residence were opened. The residence combines the use of high-tech, accessible automation with specially tra...

AT 1501, Part 1: The Science Behind the Drug from 2020-08-11T14:28:15

AT-1501 is an ALS treatment invented by ALS TDI. In 2018, became the first drug invented by a non-profit biotech to be tested in humans. In November of 2019, it successfully completed a Pha...

Dr. Steve Perrin: What is a Clinical Trial? from 2020-07-07T15:26:53

Today on Endpoints, ALS TDI CEO Dr. Steve Perrin joins us to answer some frequently asked questions about clinical trials: how the process works, and what you can – and can’t –...

Dr. Steve Perrin: What Does it Mean to Replicate or Validate a Study? from 2020-06-03T16:49

At ALS TDI, our mission is to find effective treatments for ALS. Often that involves trying to invent new drugs of our own, but it can also mean trying to see if treatments developed by others a...

Day by Day: The Reich Family Fights ALS from 2020-05-29T13:39

When Corey Reich was diagnosed with ALS in 2007, at the age of 21, his family – his sister Clare, and their parents Ted and Wendy – knew they would do whatever they could to support ...

The Lloyd Brothers: Racing for ALS from 2020-02-07T19:52

Today we’re joined by David and Scott Lloyd, the brothers behind Racing for ALS. Growing up, David and Scott shared a love of fast cars, but as they got older, began careers, and had famil...

What to Know About CMAP from 2020-01-27T16:35

 In this episode of the Endpoints Podcast, Dr. Theo Hatzipetros, the Director of Pharmacology at the ALS Therapy Development Institute ( Listen

What to know about AMX0035 from 2019-10-31T17:21:05

In this episode of the Endpoints, Dr. Steve Perrin, CSO at the ALS Therapy Development Institute, sits down to talk about AMX0035, a drug consisting ...

Collin Hadley: Choosing to use Mechanical Ventilation for ALS from 2019-10-16T13:10

In this episode of the Endpoints, Collin Hadley joins Gabrielle Bellitti, Outreach and Engagement Specialist at ALS TDI, to talk about living with ALS and using mechanical ventilation. Coll...

Samantha Van Saun: Building an ALS Community from 2019-10-15T20:08:07

In this episode of the Endpoints Podcast, Dileep Dadlani, Development Director at ALS TDI is joined by Samantha Van...

NurOwn and the Hope for Stem Cells in ALS? from 2019-10-15T19:59:14

On this episode of the Endpoints, Dr. Steve Perrin, CEO at ALS TDI answers questions about one of the most talked about clinical trials in ALS at the moment, Br...

Tamara Hillard: Anticipating Needs as an ALS Caregiver from 2019-10-15T19:46:54

In this episode of the Endpoints, Tamara Hilliard, from Fort Worth, Texas, talks about the challenges of caring for her husband, Jim, who’s liv...

Jeff Roosa: Uniting First Responders to End ALS from 2019-09-18T15:16:37

In this episode of the Endpoints, Jeff Roosa, Lee, MA Chief of Police, joins Gabrielle Bellitti, Outreach and Engagement Specialist at ALS TDI, to talk about living with ALS and unitin...

What to know about CuATSM clinical trials from 2019-09-18T15:13:06

In this episode, Dr. Fernando Vieira, CSO at the ALS Therapy Development Institute (ALS TDI), joins us to discuss Copper ATSM (CuATSM)clinical trials. CuATSM is a small molecule drug sponsored b...

What Do We Know About C9ORF72? from 2019-09-18T15:07:47

In this episode of the Endpoints, Dr. Fernando Vieira explains what we know so far about C9ORF72, a gene which has been implicated in up to 40% of cases of familial ALS. C9ORF72was discovered to...