Freely Filtered 005 IgA Nephropathy - a podcast by NephJC Team

Joel Topf

Jennie Lin

Matt Sparks

Swapnil Hiremath

Show Notes: IgA Nephropathy Score

Levi Strauss: https://www.biography.com/fashion-designer/levi-strauss

Levey MDRD study: https://www.ncbi.nlm.nih.gov/pubmed/10075613

ADPKD Total Kidney Volume: https://www.nejm.org/doi/10.1056/NEJMoa054341

Halt PKD: https://www.nejm.org/doi/full/10.1056/nejmoa1402685

Tempo 3:4 Trial: https://www.nejm.org/doi/full/10.1056/NEJMoa1205511

Description description of IgA nephropathy by Berger and Hiunglais: https://www.ncbi.nlm.nih.gov/pubmed/4180586

The reprint in JASN in 2000 with commentary as part of the Milestones in Nephrology series: https://jasn.asnjournals.org/content/jnephrol/11/10/1957.full.pdf JASN supplies an English translation from the original French.

Nice reference from JASN backing up Matt’s assertion that preeclampsia and not IgA nephropathy is the most common glomerular disease in the world: https://jasn.asnjournals.org/content/18/8/2281

Description of the Singapore Army screening recruits from the Oxford Textbook of Clinical Nephrology: https://books.google.com/books?id=fVItBQAAQBAJ&lpg=PA485&ots=JRoOnUnleT&dq=singapore%20kidney%20biopsy%20army&pg=PA485#v=onepage&q&f=false

Description of the Japanese glomerulonephritis screening program: https://cjasn.asnjournals.org/content/2/6/1360

Swapnil’s studies on autopsy studies:

Finland: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC501386/

Japan: https://www.ncbi.nlm.nih.gov/pubmed/12753320/

Nephrology Secrets, either one of the best or the best nephrology textbooks ever: https://www.amazon.com/Nephrology-Secrets-Book-Edgar-Lerma-ebook/dp/B079TSYNQW/ref=sr_1_1

TESTING Trial on NephJC: http://www.nephjc.com/news/2017/8/28/testing

Stop-Iga Trial on NephJC: http://www.nephjc.com/iga-nephropathy

Testing Trial two: Therapeutic Evaluation of Steroids in IgA Nephropathy Global Study Low Dose Study: https://clinicaltrials.gov/ct2/show/NCT01560052

MEST Score versus MEST-C in NephJC: http://www.nephjc.com/news/2016/10/16/do-crescents-matter-for-iga-nephropathy

Nice discussion of the statistical tests during the Tweet Chat by people who know their stats (I.e. not Joel): https://twitter.com/NephJC/status/1133546750814367746

Tweet-length description of IDI: https://twitter.com/kiwiskiNZ/status/1133595698929098752

Assessing the performance of prediction models: a framework for traditional and novel measures. https://www.ncbi.nlm.nih.gov/pubmed/20010215/

Net Reclassification Indices for Evaluating Risk-Prediction Instruments: A Critical Review https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918180/

Predicting Progression in CKD: Perspectives and Precautions https://www.ajkd.org/article/S0272-6386(15)01413-4/abstract

The Article by Nancy Cook in Circulation that Jennie was talking about: Use and misuse of the receiver operating characteristic curve in risk prediction. https://www.ncbi.nlm.nih.gov/pubmed/17309939

Discovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogens https://www.nature.com/articles/ng.3118

Genome-wide polygenic risk predictors for kidney disease https://www.nature.com/articles/s41581-018-0067-6

Where does Matt find minutia like the grams of IgA produced a day? Here: https://www.annualreviews.org/doi/abs/10.1146/annurev-pathol-011110-130216

Animal models of IgA nephropathy: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337240/

Matt’s Book Originals: https://www.amazon.com/gp/product/014312885X/ref=dbs_a_def_rwt_bibl_vppi_i1

Eric Neilson, Dean of Northwestern University https://www.feinberg.northwestern.edu/faculty-profiles/az/profile.html?xid=23239

Brussels sprout Insta-famous dog and future dean of the medical school: https://www.instagram.com/brussels.sprout/?hl=en

Josh Farkas Rantorial about Contrast Nephropathy: https://twitter.com/PulmCrit/status/1134922050794139648

Swapnil’s Tweetorial about Contrast Nephropathy: https://twitter.com/hswapnil/status/1133906398096609280

Tukaram’s pic of NEJM’s progression from Contrast Induced Nephropathy to Contrast Associated Nephropathy: https://twitter.com/tukaramj/status/1135214980985266178

Zero sodium dialysate for heart failure? https://twitter.com/i/moments/1134811009217155072

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