Antibiotics, Statins and Pneumonia, Neurosurgery for Epilepsy - a podcast by BBC Radio 4

The Chief Medical Officer has warned of a "post-antibiotic apocalypse" and "the end of modern medicine". As antibiotic resistance increases, the options to treat potentially deadly infections reduces. Inside Health's Dr Margaret McCartney discusses the latest campaign by Public Health England to remind us all not to take antibiotics when they're not needed.

It's been over thirty years since there was a breakthrough in the treatment of pneumonia, but that could soon change....and from an surprising source. Researchers in Birmingham at Queen Elizabeth Hospital have been working with the cholesterol-lowering drugs, statins, and discovered that this medication can turbo-charge our immune systems, helping us to fight infection. Dr Liz Sapey, respiratory consultant and researcher tells Dr Mark Porter about the exciting possibility of tablets that cost just a few pence each, being used to treat potentially deadly lung infections like pneumonia.Epilepsy is normally controlled by anti-seizure medication but for a third of patients, pills don't work, and constant fits can have a devastating impact on the developing brain. Neurosurgery - removal or disconnection of parts of the brain where the seizures originate - is now done at a much younger age in patients with untreatable epilepsy. Operating on children takes advantage of brain plasticity. Mark visits Bristol Children's Hospital, one of four national centres which since 2011 have offered increased access to epilepsy surgery. Paediatric neurosurgeon Mike Carter is part of the national drive to operate on children before they are two years old, all to take advantage of brain plasticity. Mark meets 8 year old Lucy, 20 days after she had major surgery to remove a finger-nail sized portion deep in her brain. Lucy's father, Mark Nettle, describes how, before surgery, his daughter had suffered from multiple daily seizures with increasing weakness down the left side of her body. The possibility of ending these debilitating attacks made surgery an attractive option.

Producer: Fiona Hill.

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