Podcasts by JNNP podcast

CGRP in migraine: current therapeutics, future implications and potential off-target effects from 2021-12-21T19:33:39

In this podcast, JNNP's Podcast Editor, Colin Mahoney, interviews Dr Jason Ray (Neurology, Alfred Health, and Department of Neuroscience, Monash University, Melbourne). Dr Ray discusses the role of...

Alemtuzumab's impact on functional and structural integrity of the visual system in MS from 2021-11-17T16:09:35

Prof Michael Barnett, Director Sydney Neuroimaging Analysis Centre and Professor of Neurology, University of Sydney, joins JNNP's Podcast Editor, Colin Mahoney, to discuss how the use of Alemtuzuma...

Guidelines for the management of functional speech and communication disorders from 2021-09-27T10:56:31

A/Prof Jan Baker, Speech Pathologist, Flinders University and UTS. Dr Laura McWhirter, University of Edinburgh joins editor Colin Mahoney to discuss the first comprehensive guidelines develope...

The impact of traumatic brain injury on neurocognitive outcomes in children from 2021-08-31T06:58:52

Mark Goh and Shu-Ling Chong, Duke-NUS Medical School and KK Women's and Children's Hospital, Singapore joins editor Colin Mahoney to discuss their systematic review and meta-analysis spanning 60...

Cerebral Microbleeds: from depiction to interpretation from 2021-07-05T09:58:49

Cerebral Microbleeds are increasingly recognised due to increased availability of neuroimaging and are known to be associated with increased risk of stroke, in particular intracerebral haemorrhage....

Motor functional neurological disease, a decade of progress from 2021-06-25T06:31:20

Over the last ten years, huge progress has been made in the common but often poorly understood condition of motor Functional Neurological Disorder (mFND). In this podcast, Dr W. Curt La France, Jr....

COVID - 19 Vaccination and risk of large vessel arterial stroke from 2021-06-03T07:24:46

The Oxford Astra Zeneca vaccine has been associated with a rare complication of cerebral venous sinus thrombosis. Dr Colin Mahoney, JNNP Podcast Editor, interviews Prof David Werring, Professor of ...

Drug repurposing for progressive multiple sclerosis from 2021-03-02T08:44:29

Prof Alaisdair Coles and Dr Nick Cunniffe, The University of Cambridge joins editor Colin Mahoney to discuss:

The work carried out by a team of researchers alongside the MS Society in the United...

Isaacs syndrome the crossroads of Neurology, Psychiatry and Immunology from 2020-11-25T11:48:16

Rick Thurbon, patient editorial board member. Prof Matthew Kiernan and A/Prof Susanna Park from The University of Sydney joins editor Colin Mahoney to discuss:

In 1960 a landmark paper was publi...

Apathy, cerebral small vessel disease and future dementia risk from 2020-09-28T11:18:21

Jonathan Tay joins our podcast editor Colin Mahoney to discuss the findings from two large cohort studies of cerebral small vessel disease, highlighting the fact that apathy can predict future d...

Performance validity tests - Their role in neuropsychology assessments from 2020-09-14T10:39:10

Dr Laura Mc Whirter joins our podcast editor Colin Mahoney to discuss her recent systematic review of performance validity tests used across a range of neurological and psychiatric disorders. Ar...

Parkinson's disease: etiopathogenesis and treatment from 2020-08-18T07:59:46

Prof Joseph Jankovic, Distinguished Chair in Movement Disorders, Baylor College of Medicine joins Podcast editor Colin Mahoney.

Prof Jankovic provides a historical look back on the key developmen...

Outcome measurement in functional neurological disorder a systematic review and recommendations from 2020-07-20T08:45:29

Dr Timothy Nicholson joins Podcast editor Colin Mahoney to discuss their recent systematic review of outcome measures used across the spectrum of functional neurological disorders. As well as id...

Clinical profiles of patients with dementia and chronic traumatic encephalopathy from 2020-06-22T10:21:35

Dr Christian Lobue, lead author joins Podcast Editor Colin Mahoney to discuss his original research which examines the clinical, neuropsychological and neuropsychiatric features of those with co...

Visual hallucinations in neurological and ophthalmological disease from 2020-05-27T08:43:34

Prof John O'Brien (University of Cambridge) and Dr Dominic Ffytche (Kings College London) join Dr Colin Mahoney (Podcast Editor)

Visual hallucinations have complex origins and can have significan...

Primary Lateral Sclerosis: new consensus criteria from 2020-05-12T07:28:39

Prof Martin Turner, University of Oxford, joins Dr Colin Mahoney to discuss the newest consensus clinical criteria to aid in the diagnosis of Primary Lateral Sclerosis. This will enable neurologis...

Neurology in the time of COVID - 19 from 2020-05-04T16:08:19

Dr Hadi Manji joins Colin Mahoney to discuss the recent paper by Liu and colleagues as well as providing a commentary on how COVID-19 may impact the nervous system and steps to mitigate this. He al...

Lithium: a slow burner from 2020-04-20T08:14:23

Prof Andrew Lees, Professor of Neurology National Hospital for Neurology and Neurosurgery. Colin Mahoney JNNP Podcast Editor As part of our 2020 Vision centenary Prof Andrew Lees reviews how Lithiu...

Plasma glial fibrillary acidic protein is raised in progranulin-associated frontotemporal dementia from 2020-03-26T09:02:10

Colin Mahoney, JNNP Podcast editor, is joined by Dr Jonathan Rohrer, MRC Clinician Scientist, Dementia Research Centre, UCL Institute of Neurology. Carolin Heller, Dementia Research Centre and U...

Multifocal motor neuropathy: controversies and priorities from 2020-03-05T14:15:44

Prof Bruce Taylor, Menzies Institute for Medical Research, University of Tasmania and Dr Colin Mahoney JNNP Podcast editor

Prof Bruce Taylor joins our podcast editor Colin Mahoney to discuss rece...

Multiple Systems Atrophy: the nature of the beast revisited from 2020-02-12T10:11:39

As part of our 2020 Vision Series reviewing the most seminal papers in JNNP's past Prof Niall Quinn, joins Colin Mahoney to discuss his 1989 paper which provided the first clinical criteria for ...

Employment and MS - a patient's perspective from 2020-01-15T10:34:56

Sharon Roman, a patient advocate who suffers with Multiple Sclerosis, discusses the complexities of measures of disease activity and employment in MS. https://jnnp.bmj.com/content/91/1/5

Approaches to Chemotherapy induced peripheral neurotoxicity from 2019-12-02T09:29:10

Dr Susanna Park joins Colin Mahoney to discuss neurophysiological, imaging and other methods to study an increasingly recognised problem of chemotherapy induced peripheral neurotoxicity. Dr Park ou...

Neural circuitry of anxiety from 2019-11-18T10:22:19

Dr Oliver Robinson joins Colin Mahoney to discuss the neural circuitry of anxiety, outlining our current understanding the anatomical basis for anxiety, as well as paradigms used to explore the sha...

Dementia after traumatic brain injury from 2019-10-30T08:31:51

Dr Neil Graham and Prof David Sharp, from Imperial College London, discuss the interaction between traumatic brain injury and dementia. They outline the epidemiology, pathogenesis and emerging b...

Mindfullness in multiple sclerosis from 2019-09-27T13:37:45

Dr Robert Simpson (University of Glasgow, UK) discusses the merits and limitations of mindfullness based treatments for mental well-being in Multiple Sclerosis (MS). Read the full paper here: ht...

CIDP an update from 2019-09-11T09:37:14

Professor Helmar Lehmann (University Hospital of Cologne) provides an update on Chronic inflammatory demyelinating polyneuropathy (CIDP) and discusses recent advances in diagnosis and treatment....

Movement disorders and seizures from 2019-08-15T09:05:05

Elizabeth Highton (podcast editor) is joined by Professor Alfonso Fasano (Toronto Western Hospital, Ontario, Canada) to discuss the overlapping phenomenology and diagnostic challenges in movemen...

The role of functional neuroimaging in functional neurological disorders from 2019-07-31T08:27:25

Dr. David Perez (Massachusetts General Hospital, USA) speaks with JNNP Podcast Editor, Elizabeth Highton about stepwise functional connectivity, a novel brain imaging technique, and how it might...

Emotional processing in functional neurological disorder (FND) from 2019-06-12T09:24:02

Dr. Susannah Pick (King’s College London, UK) discusses emotional processing in functional neurological disorder, and how further understand of emotional processing deficits may help contribute ...

Can cocoa help with fatigue in MS from 2019-05-28T11:11:41

Dr Shelly Coe (Oxford Brookes University, Oxford) discusses a new randomized control trial looking at the use of cocoa for management of fatigue in multiple sclerosis. Read the full paper here: ...

Neurorehabilitation in chronic stroke from 2019-05-08T08:52:10

JNNP Associate Editor, Professor Nick Ward (Queens Square, London) tells us all about the Queen Square Upper Limb Neurorehabilitation programme, and specifically, what clinical gains in chronic str...

The real patient value from 2019-04-18T09:38:11

The JNNP recently launched the patient editorial board in an effort to drive more meaningful patient outcomes. One of our newly appointment board members, Sharon Roman (Vancouver Canada) discuss...

Medical conferences - what do we get out of them? from 2019-04-04T09:33:53

A special edition podcast - based on an essay discussing the value of medical conferences and whether it is time to consider what is gained from these events, and for whom. Emeritus Professor Mi...

Oral immunotherapies in MS a comparison of efficacy. from 2019-03-25T10:03:56

Associate Professor Tomas Kalincik (University of Melbourne, Australia) discusses oral immunotherapies, and what we know about the effects of these treatments on patient relapse and disability. ...

Therapeutic trial design in frontotemporal dementias from 2019-03-20T10:25:25

Editor’s Choice: Associate Professor Dr Mario Masellis (University of Toronto) and Assistant Professor Philippe Desmarais (University of Montreal) discuss the complexities of designing trials in...

Do genes affect age of onset in ALS? from 2019-03-11T09:57:09

Professor Ammar Al-Chalabi (King’s College London, London, UK) joins Elizabeth Highton (podcast editor) to discuss motor neurone disease, also known as amyotrophic lateral sclerosis or ALS, a ra...

The lifetime risk of common neurological disorders in the elderly population from 2019-02-18T11:12:53

We have a good understanding of our risk of developing cancer or heart disease – but what do we know about the risk of developing a common neurological disorder in later-life? Dr. Silvan Licher ...

PMA and PLS: are they really restricted phenotypes? from 2019-02-04T14:11:21

Dr. Michael van Es (University Medical Center Utrecht, Netherlands) examines whether cognitive and behavioural changes can be seen across the motor neurone disease spectrum, and how this helps i...

Statins and the risk of recurrent intracerebral haemorrhage (ICH) – what does the evidence say? from 2019-01-21T11:49:06

Do statins increase the risk of intracerebral haemorrhage (ICH) in patients with a previous stroke? Professor David Werring (Stroke Research Centre, UCL Institute Of Neurology, Queen Square, Lon...

Functional impairment and improvement from 2018-12-10T11:06:53

Elizabeth Highton (podcast editor) hosts the final JNNP podcast for 2018, an episode on functional improvement after stroke (Dr. Aravind Ganesh, University of Oxford, UK- https://jnnp.bmj.com/co...

Can computational models help us understand complex movement disorders? from 2018-10-29T09:52:58

Professor Mark Humphries (University of Nottingham, UK) discusses how computational modelling could be a crucial tool in untangling the complexities of diseases like Parkinson’s disease. Can thi...

Idiopathic intracranial hypertension: guidelines for diagnosis and management from 2018-10-08T10:08:13

In collaboration with many different specialists, professions and patient representatives, Mollan et al (2018) have developed the first ever guidelines for the investigation and management of i...

Nusinersen for SMA from 2018-08-29T10:29:31

Elizabeth Highton (JNNP Podcast Editor) speaks with Dr. Michelle Farrar (University of New South Wales) discussing nusinersen, the first disease-modifying therapy for spinal muscular atrophy typ...

Expanding clinical spectrums in both Kennedy's disease and poststroke syndromes from 2018-08-06T10:08:45

Dr. Carlo Rinaldi (University of Oxford) discusses how the traditional view of Kennedy’s disease is evolving, to extend beyond pure motor symptoms. What non-motor features may be present in Kenn...

The use of cannabis in epilepsy, and surgery for tremor from 2018-07-02T13:20:45

Around 20-30% of patients with epilepsy can demonstrate resistance to commonly used medications. Cannabidiol (CBD) is a compound found in cannabis, which can be used for the treatment of epilepsy, ...

Epilepsy an evidence update from 2018-05-31T08:13:57

Is the mesial temporal lobe the seat of psychosis in epilepsy? James Allebone (University of Melbourne, Australia) discusses what neuroimaging can tell us about psychosis in epilepsy. Read the pape...

Evolution or revolution? Should we re-think clinical practice? from 2018-04-30T13:37:26

Do old habits of screening for potassium channel antibodies stand up to scrutiny? Should clinical neurologists focus on screening for LGI1 and CASPR2 antibodies? Professor Sarosh Irani (John Radcli...

The Use of Frankincense Extract In MS from 2018-04-04T12:44:51

Patients with multiple sclerosis (MS) often show interest in complementary and alternative medicines, particularly when on long-term anti-inflammatory treatments. Is frankincense a safe and tolerab...

A new questionnaire to measure quality of life in inflammatory neuropathies from 2018-03-07T12:39:24

Quality of life (QoL) is one of the most important outcomes for chronic diseases, although it remains remarkably difficult to quantify. Dr. Thomas Draak (Maastricht University, The Netherlands) di...

Marriage and a reduced risk of dementia from 2018-02-28T13:14:11

Recent research has indicated that being married is associated with a reduced risk of dementia. What is it about marriage? Dr Andrew Sommerlad (University College London) discusses this question...

Anti-inflammatory approaches to stroke prevention; monitoring disease progression in ALS from 2018-02-08T13:19:34

Atherosclerosis is a major contributor to increased risk of stroke. Our patient’s choice, Professor Peter Kelly (University College Dublin, Dublin, Ireland) discusses the evidence base implicating ...

Nodes and paranodes; alternative treatments in MS from 2018-01-26T01:25:36

People with multiple sclerosis (MS) use complementary and alternative treatments (CAM), but what does the evidence say? Patient’s Choice, Professor Bruce Taylor (University of Tasmania) discusses t...

Pathophysiology of functional neurological disorder from 2017-12-13T11:26:18

Despite the prevalence of the disease, neurologists and psychiatrists can be wary of treating patients with functional neurological disorder (FND). Assistant Professor David Perez (Massachusetts...

Is methamphetamine use linked to stroke in young adults? from 2017-11-28T10:32:21

Is methamphetamine use linked to strokes in young adults? Important clinical implications discussed by Dr. Julia Lappin (University of New South Wales) in this month’s JNNP podcast.

http://jnnp.b...

Cerebral Amyloid Angiopathy: New Insights For Clinical Practice from 2017-11-08T09:35:18

Cerebral amyloid angiopathy (CAA) has been gaining attention over the past few years, thanks to increased research in the field. Professor David Werring (UCL Institute of Neurology, Queens Squar...

Cortical Influences in ALS from 2017-10-31T08:30:36

Professor Emeritus Andrew Eisen (University of British Columbia, Canada) discusses the theory of corticofugal primary in amyotrophic lateral sclerosis. ALS can be viewed as a primarily human dis...

Intravenous immunoglobulin in CIDP from 2017-10-23T10:04:24

Can IViG be used as a longer term maintenance therapy for CIDP patients? JNNP Associate Editor, Professor Satoshi Kuwabara (Chiba University Hospital, Japan) joins us for this podcast, discussin...

Complex inherited neuropathies: a new approach to diagnosis? from 2017-10-18T08:18:26

Professor Mary Reilly (Institute of Neurology, Queens Square, London) discusses how complex inherited neuropathies can be a daunting diagnosis for clinicians. However, through exciting advances ...

Cerebellum and neurodegeneration; autoantibodies and psychological development in children from 2017-09-04T22:37:37

The September 2017's JNNP podcast is a double episode. The first conversation is with Professor Michael Hornberger from the Norwich Medical School, University of East Anglia, UK. The cerebellum is ...

Time Matters - part 2: how the real costs of multiple sclerosis are being concealed from 2017-08-07T17:29:34

“Take a comprehensive economic approach to evaluating treatment cost-effectiveness in MS”. Jacqueline Palace (Consultant Neurologist, Nuffield Department of Clinical Neurosciences, University of Ox...

Survival and cause of death in Multiple Sclerosis from 2017-07-19T08:20:24

There has been an increase in life expectancies for the general population over the last few decades. A similar trend has also been identified in patients with Multiple Sclerosis (MS). To investig...

Time Matters - part 1: delay is “expensive” in all aspects of multiple sclerosis from 2017-07-10T10:51:48

Professor Emeritus Alastair Compston (University of Cambridge) discusses with JNNP’s Publisher Janet O'Flaherty the issues raised by the discussion “Brain health matters in multiple sclerosis” (MS)...

Seven tesla MRI In Neurodegenerative Dementias from 2017-06-16T07:17:34

MRI is an important clinical tool to study dementia symptoms in vivo. However, certain pathologies (microbleeds, plaques, tangles) can evade current imaging techniques. Seven tesla (7T) MRI provide...

Conversational Laughter In Dementia from 2017-05-05T08:26:26

Laughter serves a fundamental social purpose, the appropriate use of which requires recognition of social norms. So what happens when these interpersonal abilities are affected, such as in the f...

Narrative and Neurology: The Andrew Lees Experiment from 2017-04-06T16:42:34

Professor Andrew Lees discusses his book "Mentored by a Madman: The William Burroughs Experiment" with Dr Sean O’Sullivan and Elizabeth Highton. Andrew speaks to the importance of looking beyond on...

April 2017: deconstructing dilemmas in Amyotrophic Lateral Sclerosis and Guillain-Barré Syndrome from 2017-03-27T11:43:32

Both patient and editor's choices are discussed in this monthly episode of the JNNP podcast. The clinical care of patients with Guillain-Barré syndrome (GBS) can often be complex; a disease with a...

Zika virus and Guillain-Barré Syndrome: what do we know? from 2017-03-13T17:29:10

There is concern that, despite being a rare complication of the Zika virus, we could see a steady rise in the number of cases of Guillain-Barré Syndrome (GBS). In preparation for this, it is import...

Immunomodulatory therapy in advanced multiple sclerosis from 2017-02-13T14:44:20

Could currently available immunomodulatory therapies modify disability trajectories in patients with moderately advanced and advanced multiple sclerosis (MS)? Tomas Kalincik, Department of Medicin...

The relationship between orthostatic hypotension and cognitive impairment in ?-synucleinopathies from 2016-11-30T16:34:22

Dr Mario Masellis and Dr. Sean Udow from the Sunnybrook Health Sciences Centre, University of Toronto, Canada, look at the potential association between orthostatic hypotension and cognitive impair...

A clinical tool for predicting survival in motor neurone disease from 2016-11-30T13:22:59

Elizabeth Highton spoke to Professor Ammar Al-Chalabi from King’s College London about the development of a simple and clinically useful graphical model of predicting survival for motor neurone dis...

Latitude and disease severity in Multiple Sclerosis from 2016-11-15T17:31:54

Elizabeth Highton and Prof. Bruce Taylor discuss higher latitudes and its association with earlier age of onset of Multiple Sclerosis (MS). The international study, published by the JNNP, links la...

Do your kids play rugby? Risks for rugby union players from repeated concussions from 2016-11-07T17:16:15

Associate Editor of JNNP Alan Carson interviews Tom McMillan, Professor at the Institute for Health&Wellbeing, University of Glasgow, UK, about the paper "Long Term Health Outcomes after Exposure t...

Genetics and the clinical course of multiple sclerosis from 2016-10-18T10:46:43

Professor Bruce Taylor and Elizabeth Highton discuss how certain genetic risk variants may predict the clinical course and progression of Multiple Sclerosis.

This podcast relates to the Patient C...

Is it time to focus on the common pathways linking neurodegenerative diseases? from 2016-10-13T13:05:06

Dr. Rebekah Ahmed talks about her recent JNNP review: Neuronal network disintegration and the common pathways linking neurodegenerative diseases. Dr. Ahmed and colleagues critically evaluate a new...

October 2016 Edition: long-term outcomes after stroke; hereditary and inflammatory neuropathies from 2016-09-22T13:41:40

In this JNNP podcast, Elizabeth Highton speaks with Dr. Siobhan Crichton and Dr. Benjamin Bray about their study looking at patient outcomes up to 15 years after stroke. Read their full paper here...

Selective vulnerability in clinical variants of Alzheimer's Disease from 2016-08-30T14:24:57

Elizabeth Highton spoke with Professor Henrik Zetterberg from Sahlgrenska University in Sweden. They discuss his recent JNNP review looking at clinical variants of Alzheimer's Disease and whethe...

Smoking: a negative prognostic for survival in motor neurone disease patients from 2016-08-19T14:11:08

Elizabeth Highton is joined by Prof. Adriano Chio to talk about his study: Influence of cigarette smoking on ALS outcome: a population-based study.His large population-based cohort study of patient...

Review: Amyotrophic Lateral Sclerosis and Motor Neuron Syndromes in Asia from 2016-07-27T16:45:47

In this podcast, Dr Nortina Shahrizaila, a neurologist from the University of Malaya, talks about her review regarding Amyotrophic lateral sclerosis and motor neuron syndromes in Asia. She discusse...

Automated brain volumetrics in multiple sclerosis, plus migraine and psychiatric co-morbidities from 2016-06-30T13:38:43

In this July podcasts, Associate Professor Michael Barnett explains the details of his short report comparing Structural Image Evaluation using Normalisation of Atrophy-Cross Sectional (SIENAX) to ...

Coffee consumption and multiple sclerosis from 2016-06-07T14:13:59

Can coffee impact on the health of neurons? And what are the effects of its consumption on the risk of developing multiple sclerosis? These are some of the questions Dr Ellen Mowry answers in this...

June Edition: Parkinson’s disease and the rate of ALS progression from 2016-05-24T10:48:20

In this podcast, Elizabeth Highton investigates the details of two studies selected for the June 2016 edition of JNNP. Professor Steve Vucic, from the Department of Neurology at Westmead Hospital,...

Sudden Unexpected Death in Epilepsy: basic mechanisms and implications for prevention from 2016-04-08T09:10:42

In this podcast, Dr Brian J Dlouhy explains the mechanisms behind sudden unexpected death in epilepsy (SUDEP), one of the most common cause of death in patients with intractable epilepsy. “Sudden u...

Re-evaluating the treatment of acute optic neuritis from 2016-02-10T16:36:32

In this podcast, Professor Elliot Frohman discusses the treatment of acute optic neuritis and its connection with multiple sclerosis. Elliot Frohman is Professor of Neurology and Neurotherapeutics ...

BNPA 2015: Spatial Neglect from 2015-06-08T09:30:37

Kieran O'Driscoll, Neuropsychiatrist, Manchester, speaks to Giuseppe Vallar, Professor of Psychobiology and Physiological Psychology, University of Milano-Bicocca, about spatial neglect.

This pod...

BNPA 2015: New theories of memory systems and networks from 2015-06-08T08:56:30

Chris Butler speaks to Adam Zeman about new theories of memory systems and networks.

This podcast was recorded at the 2015 BNPA AGM.

BNPA 2015: Phantom phenomena from 2015-02-24T13:47:30

David Linden, neuropsychiatrist, Cardiff, Wales, talks to Peter Brugger, Department of Neurology, University Hospital Zurich, about phantom phenomena.

This podcast was recorded at the BNPA 2015 A...

Clinical neurology: why this still matters in the 21st century from 2015-01-27T15:35:11

David Nicholl argues that even with the tremendous advances in diagnostic neuroimaging that the clinical skills involved in clinical neurology remain key. In a recent JNNP review he writes that rec...

Imaging outcomes for trials of remyelination in multiple sclerosis from 2014-12-11T12:32:25

Trials of potential neuroreparative agents are becoming more important in the spectrum of multiple sclerosis research. Appropriate imaging outcomes are required that are feasible from a time and pr...

BNPA 2014: Oxytocin and social cognition from 2014-12-02T16:47:45

Individual differences in our capacity to read other people’s emotions and to remember faces we have seen before are highly variable in the general population. Some people are super-recognizers; ot...

BNPA 2014: Schizophrenia and cognition from 2014-12-02T16:36:33

Cognitive impairment is generally considered an important facet of the schizophrenia syndrome but how fundamental is it? In this podcast Alan Carson discusses the question with Eileen Joyce, Cons...

Advances in epilepsy surgery from 2014-11-27T12:19:31

Exciting recent and forthcoming advances will impact on the surgical management of epilepsy in the near future. Mark Nowell and John Duncan, both Department of Clinical and Experimental Epilepsy, ...

Brain atrophy and disability progression in multiple sclerosis patients from 2014-10-13T14:39:53

Dr Robert Zivadinov, Department of Neurology, School of Medicine and Biomedical Sciences, Buffalo Neuroimaging Analysis Center, discusses his paper which aimed to identify MRI biomarkers associated...

BNPA 2014: Joint hypermobilty and autonomic hyperactivity from 2014-09-17T16:40:59

Chis Butler, MRC Clinician Scientist and Honorary Consultant Neurologist at the University of Oxford, talks to Jessica Eccles, MRC Clinical Research Training Fellow, Brighton and Sussex Medical Sch...

BNPA 2014: Post-Ictal psychosis from 2014-09-17T16:34:26

Hugh Rickards, consultant in Neuropsychiatry and honorary reader in Neuropsychiatry at Birmingham University, talks to Georgy Pius, ST6 Trainee, North West Deanery, about his case-control study exa...

BNPA 2014: TREM2 variants and risk of dementia from 2014-09-17T16:30:28

Chris Butler, MRC Clinician Scientist and Honorary Consultant Neurologist at the University of Oxford, talks to Catherine Slattery, Clinical Research Associate, Institute of Neurology, about her wo...

Neurosurgical procedures for psychiatric illness from 2014-09-17T16:16:15

This month, how to safely and ethically carry out stereotactic surgery for psychiatric illness. Bart Nuttin, Department of Neurosurgery, University of Leuven, has put together pragmatic guidelines...

Can stress trigger Parkinson's? And new criteria for frontotemporal dementia syndromes. from 2014-08-05T15:15:30

Does emotional stress trigger Parkinson's disease? Andrew Lees, Reta Lila Weston Institute of Neurological Studies, talks us through the evidence so far.

And Glenda Halliday, Neuroscience ...

HIV and multiple sclerosis: beginning to unravel a mystery from 2014-07-02T15:58:34

Julian Gold, professor in the department of neuroscience and trauma, Queen Mary, University of London, and senior staff specialist, Albion Centre, Prince of Wales Hospital, Sydney, discusses his...

BNPA 2014: Neuropsychiatry of social knowledge and moral motivation from 2014-06-24T18:12:43

JNNP editor Alan Carson asks Roland Zahn, senior clinical lecturer, King's College London, about the neuroanatomy of moral behaviour, particularly his work into the neural mechanism of moral emo...

DBS in essential tremor, and genetic counselling for ALS from 2014-05-22T16:44:32

This month, genetic counselling for amyotrophic lateral sclerosis (ALS). Adriano Chiò, Turin ALS Expert Center, ‘Rita Levi Montalcini’ University of Turin, tells us what it can and can't do, who...

Mortality and morbidity 15 years after hospital admission with mild head injury from 2014-04-30T16:39:28

Head injury is very common, and we know those admitted to hospital with a severe head injury have a high mortality rate in the proceeding year. However less is known about later mortality, and e...

Informed decision making in MS, and the striatum in neurodegeneration from 2014-04-04T13:27:35

What's the role of the striatum, in changes in cognition and behaviour in neurodegeneration? Michael Hornberger, University of Cambridge, explains why it may be more pivotal than we currently th...

BNPA special: Autoimmune encephalitis from 2014-03-14T15:49

Angela Vincent, emeritus professor of neuroimmunology at the University of Oxford, gives Adam Zeman, professor of cognitive and behavioural neurology, University of Exeter, an overview of autoi...

BNPA special: The prospects of a vaccine for Alzheimer's disease from 2014-03-13T11:07:41

Adam Zeman, professor of cognitive and behavioural neurology, University of Exeter, asks James Nicoll, professor of neuropathology, University of Southampton, about the progress being made in pr...

An unusual variant of Guillain–Barré syndrome, and dopamine dysregulation syndrome from 2014-03-04T17:48:18

This month, an unusual variant of Guillain Barre syndrome - the pharyngeal cervical brachial variant. Benjamin Wakeley, a consultant neurologist at the Gloucester Hospitals NHS Foundation trust ...

BNPA special: Impulse control disorder in Parkinson's from 2014-03-03T13:27:44

Kieran O'Driscoll, consultant neuropsychiatrist in Liverpool, talks to David Okai, a consultant in psychological medicine in Oxford and researcher at King's College London, discusses assessing a...

Diagnosing and treating functional symptoms from 2014-01-10T17:37:37

February's JNNP is a neuropsychiatry special issue, with papers on a broad range of disorders which lie between neurology and psychiatry. Associate editor Alan Carson discusses the contents, and...

Solving the case, making the diagnosis: Neurology and detective writing from 2014-01-09T17:22:02

When searching for clues to reach a diagnosis, neurologists often empathise with the detective who is trying to solve a case, write Peter Kempster and Andrew Lees in JNNP sister journal Practical N...

Radiation for brain metastases, and the genetics of ischaemic stroke from 2013-11-26T16:25:17

This month, whole brain radiation vs radiosurgery for cerebral metastases. Does the former cause significantly more cognitive defects, and are any blanket, mopping up effects worth it? Clark Ch...

Education special: Headache from 2013-11-26T16:16:14

Callum Duncan, neurologist at Aberdeen Royal Infirmary, convenes a round table of experts to discuss advances in headache, particularly the pathophysiological understanding of cluster headache, ...

Aggressive MS, and disappointment following deep brain stimulation for Parkinson's from 2013-10-25T15:03:01

This month, getting a handle on aggressive multiple sclerosis. Suresh Menon and Helen Tremlett, both from the Department of Medicine, University of British Columbia, talk us through their recent...

Vitamin D, sunlight, and MS from 2013-10-15T14:42:22

October's JNNP takes another step towards demystifying the relationship between sunlight, vitamin D, and MS, featuring a paper which reveals sun exposure may have direct effects on neurodegenera...

Education special: Neurogenetics update from 2013-10-15T14:30:09

Ralph Gregory, secretary for the Association of British Neurologists and consultant neurologist in Dorset, gets an update on neurogenetics research and implications for practice from Nick Wood, ...

Diagnosing and treating neuromyelitis optica from 2013-08-19T09:51:37

Neuromyelitis optica (NMO) is an autoimmune inflammatory disorder with predilection for the optic nerves and spinal cord. Many recent advances, in particular, the discovery of NMO-IgG, an NMO-sp...

Diagnosing the dementias from 2013-07-23T11:18:36

This month, we get an update on the latest in clinically diagnosing the dementias, with a roundtable of experts convened by the Association of British Neurologists.

Taking part are John Gr...

Anti-GQ1b antibody syndrome, and ALS and language deficits from 2013-07-05T13:23:49

We know that ALS is associated with executive dysfunction, but what about language deficits? Steven Wing, specialist neurology registrar at Addenbrooke’s Hospital, Cambridge, talks to Laura Gold...

Striatal cell transplants for Huntington’s disease: where are we now? from 2013-07-05T13:13:25

In Huntington’s disease the striatum takes a big hit early. This has prompted trials of foetal stratal transplantation, in the hope that this may provide some relief to patients.

Stevan Wi...

Education special: MS update from 2013-06-11T15:32:39

Ralph Gregory, secretary for the Association of British Neurologists and consultant neurologist in Dorset, gets an update on multiple sclerosis research and implications for practice from Neil R...

Education special: Peripheral nerve disease update from 2013-06-11T15:29:20

Ralph Gregory, secretary for the Association of British Neurologists and consultant neurologist in Dorset, gets an update on peripheral nerve disease research and practice from James Overell, co...

Stem cells in neurology, and enlarged perivascular spaces and intracerebral haemorrhage from 2013-06-11T15:25:29

Where are we with stem cell treatments for stroke and Parkinson’s disease? At the Association of British Neurologists’ recent annual meeting in Glasgow, Neil Scolding, director of the Bristol In...

Parkinson’s disease subtypes: lost in translation? from 2013-05-01T15:31:25

This month Connie Marras, assistant professor of neurology, University of Toronto, talks us through her review of Parkinson’s disease subtypes.

What definitions do we have so far, what cou...

The latest on stroke from 2013-05-01T15:30:25

In this special edition of the podcast, JNNP associate editor Nick Ward looks into some of the latest research into stroke.

Tracking cognitive function in those recovering from stroke in r...

Dopamine agonist withdrawal syndrome from 2013-05-01T15:25:16

The problem of those with Parkinson’s disease becoming addicted to dopamine replacement therapy is well know, but it’s also now emerging that some patients have trouble coming of dopamine agonis...

BNPA 2013: The impact of epilepsy on cognitive function from 2013-02-18T11:51:51

Cognitive impairment in those with epilepsy is common. Adam Zeman, professor of cognitive and behavioural neurology, University of Exeter, ask Christoph Helmstaedter, associate professor for cli...

BNPA 2013: Psychedelic drugs, magical thinking and psychosis from 2013-02-18T11:50:38

Robin Carhart-Harris, post-doctoral researcher, Division of Brain Sciences, Imperial College London, explains his hypothesis on the shared neurobiology of psychosis, psychedelic states and spont...

BNPA 2013: Decoding consciousness from 2013-02-18T11:48:39

What relevance does consciousness have for our understanding of mental conditions? Geraint Rees, deputy head of the UCL Faculty of Brain Sciences, tells Peter Halligan, professor in the School o...

BNPA 2013: Epilepsy, depression and anxiety disorders from 2013-02-18T11:47:41

There is a complex relationship between epilepsy, depression, and anxiety disorders. Adam Zeman, professor of cognitive and behavioural neurology, University of Exeter, discusses the association...

BNPA 2013: Brain networks in human epilepsy from 2013-02-18T11:46:13

How epileptic seizures start is unclear. Mark Richardson, professor of epilepsy, Institute of Psychiatry, is working on elucidating this question using computational models. He talks Markus Reub...

BNPA 2013: Cellular mechanisms of epilepsy from 2013-02-18T11:39:37

Markus Reuber, professor of clinical neurology, University of Sheffield, discusses the different cellular mechanisms which allow seizures in epilepsy to happen, and how this understanding could ...

BNPA 2013: Autoimmunity and neuropsychiatry from 2013-02-18T11:38:24

Tim Nicholson, academic clinical lecturer, Institute of Psychiatry, gives Hugh Rickards, consultant in neuropsychiatry, University of Birmingham, an update on autoimmune mechanisms and encephali...

BNPA 2013: Deep brain stimulation for mental illness from 2013-02-18T11:37:11

Eileen Joyce, professor in neuropsychiatry at the Institute of Neurology, gives Hugh Rickards, consultant in neuropsychiatry, University of Birmingham, an update on the use of deep brain stimula...

BNPA 2013: The neural correlates of Freudian “repression” in conversion disorder from 2013-02-18T11:35:42

Selma Aybek, clinician researcher, Service of Neurology, University of Lausanne, has been examining the process which allows psychological stressors to become physical symptoms in conversion dis...

BNPA 2013: Effects of early childhood posterior fossa tumours on IQ from 2013-02-18T11:34:02

Cliodhna Carroll, along with colleagues at the University of Cambridge, has shown that children who’ve had a posterior fossa tumour have a lower IQ than matched controls. She talks Chris Butler,...

BNPA 2013: Epilepsy and affective disorders, the role of the subgenual prefrontal cortex from 2013-02-18T11:31:15

Chris Butler, academic clinical lecturer in neurology, University of Oxford, talks to Rebecca Cleary, research assistant, Wellcome Trust Centre for Neuro-imaging, UCL, about her research investi...

BNPA 2013: Stress and war, and the limits of neuropsychiatry from 2013-02-18T11:29:45

Neil Greenberg, academic psychiatrist, Kings College London, who’s served in the armed forces for more than 20 years, argued in his JNNP-sponsored keynote at BNPA that we understand many of the ...

BNPA 2013: Childhood stress and risk for later mental disorder from 2013-02-18T11:28:39

David Skuse, professor in the Behavioural Sciences Unit, Institute of Child Health, talks to Jeremy Hall, professor of psychiatry and neuroscience at the University of Cardiff, about his work in...

BNPA 2013: Inflammation and mental illness from 2013-02-18T11:25:45

Alan Carson, JNNP associate editor, talks to Neil Harrison, consultant neuropsychiatrist and head of psychoneuroimmunology, Brighton and Sussex Medical School, about what we currently know about...

BNPA 2013: Posttraumatic stress disorder and the brain from 2013-02-18T11:24:13

David Skuse, professor in the Behavioural Sciences Unit, Institute of Child Health, asks Chris Brewin, professor of clinical psychology, UCL Faculty of Brain Sciences, about the different forms ...

BNPA 2013: Equipped to survive, how comprehensive response to threat enables optimal behaviour from 2013-02-18T11:16:06

The human response to threat requires comprehensive change in the network properties of the brain, with the whole organ affected. Alan Carson, JNNP associate editor, asks Guillén Fernández, dire...

Discovering Emery-Dreifuss muscular dystrophy, and flavour identification in FTLD from 2013-02-15T17:27:44

In the last JNNP podcast of 2012, we look at what jelly beans and the Andalucian mountains have done for neurology and psychiatry.

Alan Emery, emeritus professor, Green Temple College, Uni...

The future of epilepsy research, assessing hemianopia, measuring sensory nerve action potentials from 2013-02-15T17:25:12

This month, Mark Richardson, professor of epilepsy, Kings College London, relates his vision for the future of epilepsy research (1.07).

Alexander Leff, consultant neurologist, Institute o...

The Scheltens scale, disability after head injury, and cannabis for multiple sclerosis from 2013-02-15T17:19:36

This month, we explore the latest research on treating multiple sclerosis with cannabis extract. Editor Matthew Kiernan speaks to John Zajicek, professor of Clinical Neuroscience, Peninsula Coll...

Early days of the Queen Square brain bank; rating dopaminergic replacement therapy response from 2013-02-15T17:17:13

The Queen Square brain bank was set up by Andrew Lees, and whilst there he co-authored two of JNNP’s most highly cited papers – one on the importance of Lewy bodies in Parkinson’s, and the other...

Oliver Sacks’s functional paralysis; progressive multifocal leukoencephalopathy from 2013-02-15T17:14:10

In 1974 Oliver Sacks was hiking through a remote part of Norway when he suffered a nasty injury to one leg. Although he managed to get to help and was successfully operated on, he struggled to r...

Recovery after stroke; malingering after concussion from 2013-02-15T17:12:07

Derick Wade (professor and consultant in neurological rehabilitation at the Oxford Centre for Enablement) and Nick Ward (JNNP associate editor and reader in clinical neurology at UCL) discuss th...

The future of glioblastoma therapy from 2013-02-15T17:10:22

Despite current standard care for glioblastoma being aggressive, mean survival is around 14 months. Clark Chen (director of Clinical Neuro-oncology, Beth Israel Deaconess Medical Center, Boston)...

Neurological symptoms from autoimmune syndromes; movement disorders and OCD; counting strokes from 2013-02-15T17:08:43

This month, editor Matthew Kiernan discusses new guidelines for recognising central nervous system neuronal surface antibody associated symptoms with Angela Vincent (emeritus professor of neuroi...

Idiopathic intracranial hypertension; discovering the neurological effects of critical illness from 2013-02-15T17:05:51

This month Beau Bruce (assistant professor of ophthalmology and neurology, Emory University School of Medicine, Atlanta) discusses what we do and don’t know about idiopathic intracranial hyperte...

Diagnostic criteria for CBS; tractography in ALS fifty years ago; better tests for bvFTD from 2013-02-15T17:03:34

In April’s podcast, we put a spotlight on amyotrophic lateral sclerosis and frontotemporal dementia.

Maxime Bertoux, a neuropsychologist at Paris-Sorbonne University, discusses the problem...

Surrogate outcomes; CAA and IH; Angela Vincent looks back from 2013-02-15T16:59:03

This issue we look at short-term outcomes used to assess multiple sclerosis treatments, and their power to predict long-term disability, with Douglas Goodin (professor of clinical neurology, Uni...

Cerebral amyloid angiopathy; lifestyle and mortality after stroke; motor output patterns from 2013-02-15T16:55:54

This month, cerebral amyloid angiopathy. David Werring (Stroke Research Group, UCL Institute of Neurology and the National Hospital for Neurology and Neurosurgery) discusses the importance of de...

The early days of chronic fatigue syndrome research; Clues to functional weakness mechanism from 2013-02-15T16:52:22

In this first podcast of 2012 editor Matthew Kiernan talks about JNNP’s new impact commentaries - a series which will explore influential papers from the journal. A paper by Simon Wessely (King’...

Diagnosing delirium from 2013-02-15T16:49:08

This month we discuss the issue of diagnosing delirium in older hospital patients. Despite being linked to a range of poor outcomes, the syndrome is often missed and evidence on its measurement ...

Diagnosing conversion disorder; exercise to prevent falls in Parkinson’s patients from 2013-02-15T16:46:16

In this edition Richard Kanaan (Institute of Psychiatry, King’s College London) talks about his work on conversion disorder, and gives his advice for neurologists and psychiatrists on making thi...

The natural history of Parkinson’s; the latest on MS and latitude from 2013-01-29T17:28:52

Current treatments for Parkinson’s ameliorate the core, motor symptoms. However as we look for therapies to modify the underlying course of the disease there’s a need to better understand its de...

Athleticism and ALS; understanding peripherally induced movement disorders from 2013-01-29T17:20:02

Movement disorders following head trauma are well recognised, but we know much less about those occuring after a peripheral injury. Diana van Rooijen, Leiden Medical Center, the Netherlands, tel...

Thrombolysis for elderly stroke patients; disability with organically-unexplained symptoms from 2013-01-29T17:17:33

Intravenous thrombolysis is the only curative treatment for acute ischaemic stroke, but is only licensed for patients up to 80 years old. Dr Paul Guyler, Southend Hospital NHS Trust, UK, discuss...

Finger length ratio and ALS; psychotherapy for dizziness from 2013-01-29T17:11:11

Dizziness can significantly complicate peoples’ lives, especially if it does not have a satisfactory medical explanation. We talk to Dr Gabriele Schmid of the Department of Psychosomatic Medicin...

Frontotemporal dementia reviewed; temporal orientation and dementia from 2013-01-29T17:07:02

Recent clinical, neuropsychological, imaging, genetic and pathological developments have changed our understanding of frontotemporal dementia, its classification and criteria. Dr Jonathan Rohrer...

Dementia and word knowledge; DBS for Parkinson’s from 2013-01-29T16:53:13

This month Robert Wilson, Rush University Medical Center, Chicago, USA, on how dementia affects our knowledge of words, and the neuropathology which underlies this.

Also, the use of deep b...

Genes, vitamin D and MS; hysteria and hypnosis from 2013-01-29T16:48:53

It’s been known for years that the prevalence of MS increases the further you go from the equator, but not why. Roisin Lonergan, from St Vincent’s University Hospital, Dublin, Ireland, describes...

Eye movements in motor neurone disease; work and multiple sclerosis from 2013-01-29T15:02:22

This month Harriet Vickers (BMJ’s multimedia intern), talks to Solveig Glad about how long patients with benign multiple sclerosis stay in work, and what could help them hold down jobs.

Al...

October 2010 from 2013-01-29T14:57:18

In this month’s podcast Dr Amal Al Sayegh tells us about psychological therapies for treatment of post-concussion syndrome, and Dr Serena Hung describes patient’s perceptions of dyskinesia in Pa...

Predicting adjustment to an ALS diagnosis from 2013-01-29T14:53:02

Tamara Matuz discusses her research looking for predictors for how well patients adjust to a diagnosis of ALS in southern Germany.

Microbleeds and abuse in dementia from 2013-01-29T14:51:02

In this month’s podcast David Werring from University College London talks about his research into the link between brain microbleeds and intercerebral haemmorhage. Claudia Cooper explains her r...

Migrane co-morbidities from 2013-01-29T14:48:06

In this month’s podcast Dawn Buse from the Montefiore Headache Center, New York, talks about her research into co-morbidities in chronic migrane sufferers.

See also: Sociodemographic and c...

The SCAN rule from 2013-01-29T14:43:56

Matthew Kiernan (editor of JNNP) interviews Caroline Lovelock about her paper: The SCAN rule: a clinical rule to reduce CT misdiagnosis of intracerebral haemorrhage in minor stroke. This paper ...

Epilepsy and driving; Self awareness in dementia from 2013-01-29T14:16:24

In this second podcast Professor Matthew Kiernan talks to Dr Rhys Thomas about the law regarding sleep-related epilepsy and driving - this month’s editor’s choice paper.

Also Duncan Jarvie...

Pregnancy and MS from 2013-01-29T13:51:33

We are delighted to offer you the inaugural podcast from JNNP. Recorded at BMA House London, our broadcast begins with a future vision for the journal from incoming Editor, Professor Matthew Kie...