Podcasts by Mentors at Your Benchside
Bioscience Research Tips and Advice Webinars from Bitesize Bio
Further podcasts by BiteSize Bio
Podcast on the topic Naturwissenschaften
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The World of Macrophages: How to Harness Them for Research from 2019-07-23T17:15
Although macrophages were first described by Elie Metchnikoff in 1882, plenty of mysteries are still associated with the cell type. Indeed, while macrophages were once considered simply "garbage tr...
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Basics of FLIM and Applications to FRET Biosensors from 2019-06-16T19:18:12
Functional imaging is a rapidly growing field key to driving new understanding in biology. Insights into the function and interaction of molecules are the key to reveal the underlying cellular mech...
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Adding Multiplex Factor to Confocal Imaging with ZEISS LSM 9 from 2019-05-14T16:00
In this tutorial on confocal imaging, you will learn how you can:
- Capture weaker signals—and still get sound, reproducible data.
- Reach faster volumetric imaging without sacrificing...
Cryo-electron Tomography for Cell Biology from 2019-04-11T18:00
In this webinar, you will learn:
- The complete workflow for in situ cryo-electron tomography
- How subtomogram averaging within the cell yields native-state structures of macromole...
Cryo-Electron Microscopy and the Complexity of Cancer from 2019-03-28T17:00
In this webinar, you will learn:
- How structural biology can change the face of your research
- The biological challenges of cancer research
- Advantages of cryo-EM for your resea...
Fast superresolution microscopy – with Lattice SIM from 2019-03-05T16:00
Your life sciences research often requires you to measure, quantify and understand the finest details and sub-cellular structures of your sample. You may be working with tissue, bacteria, organoids...
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Array Tomography for SEM 3D Reconstruction from 2018-11-27T17:45
Array tomography (AT) is a 3D image reconstruction technique for high resolution, quantitative analysis of biological structures. For optimal results, ultrathin and ordered sections are an absolute...
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Expanding the limits of EM sample prep with ICE from 2018-11-20T17:45
In this webinar you will learn:
- Improved vitrification: Specimen vitrification without synchronisation fluid
- Vitrification strategies: Optimized freezing for different techniques
Using CRISPR/Cas9 to detect DNA sequences with AFM from 2018-11-13T17:15
Join Dr. Jason Reed as he describes a novel method by which endonuclease-inhibited Cas9 can be employed as a programmable biomarker in high-speed atomic force microscopy (HS-AFM) imaging.
...
How to Use CRISPR to Accelerate Cancer Therapies from 2018-11-01T17:30
Join Theo Roth as he describes his lab's novel CRISPR-Cas9 genome-targeting system that does not require viral vectors to modify T cell genomes, but instead focuses on HDR. This allows rapid and ef...
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Nucleic acids 101: Confirming Their Quality from 2018-10-16T16:45
Join us in this webinar as Dr. Victoria Doronina helps you determine the quality of your nucleic acids. In this webinar you will learn:
- How to choose the best method to extract your nucl...
Live Cell Isolation by Laser Microdissection from 2018-10-10T17:45
In this webinar, you will learn:
- How to best prepare your specimen for live cell isolation by laser microdissection
- How to optimize your laser microdissection workflow
- How to...
Reliable quantification of fluorescence images from 2018-10-09T16:45
In this webinar, you will learn:
- How to overcome issues with stage drift and crosstalk between channels
- How to obtain reliable images and reproducible quantification results
- ...
Crash Course: Developing a Fool-Proof ELISA from 2018-09-27T17:00
Join us in this webinar featuring Dr. Omonse Talton who will guide you through developing a "fool proof" enzyme-linked immunosorbent assay (ELISA). In this webinar, you will learn:
- When ...
Discovering PARP inhibitor resistance mechanisms with CRISPR from 2018-09-20T17:30
In this webinar, Dr. Stephen Pettitt explains how he applies genome-wide targeted mutagenesis screens to elucidate the genetic basis of drug resistance. Using mouse and breast cancer cell lines, Dr...
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14 Ways to Measure Immune Cell Activation from 2018-09-18T16:45
Activation of immune cells is the all-important first step in mounting an immune response. Immune cell activation is a popular area of research because so much happens that is key to the downstream...
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A Guide to Target Gene Validation Using Quantitative RT-PCR from 2018-09-12T16:45
While next generation sequencing enables researchers to unveil expression levels of the entire genome, qRT-PCR remains the gold standard for measuring transcript levels of individual genes for func...
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How to Ensure Your Cell-Based Assays Are Reproducible from 2018-09-05T18:30
Join us in this webinar featuring Dr. Vicki Doronina as she takes you through vital components of assay design. In this webinar you will learn:
How to choose between immortalized cells and...
Simultaneous Proteomics and Transcriptomics from 2018-08-22T17:30
Join us in this webinar featuring Dr. Marlon Stoeckius as he explains how you can improve your single-cell RNA-sequencing (scRNA-seq) experiments. In this webinar, you will learn:
- How yo...
Using qPCR to Validate Epigenetic Enrichment of Pathogen DNA from 2018-07-11T17:30
qPCR is one of the most specific and sensitive tools in molecular biology, allowing the quantification of target DNA molecules present at less than 1 in 106. Next Generation Sequencing (NGS) has si...
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Super-resolved STED spectroscopy: New insights from 2018-07-10T16:45
Molecular interactions are key in cellular signalling. They are often ruled or rendered by the mobility of the involved molecules. We present different tools that are able to determine such mobilit...
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Challenges and solutions in microbiome analysis workflows from 2018-06-28T17:00
Elucidating meaningful, unbiased microbial community profiles from complex microbiome samples is challenging. In this webinar, you will learn:
– the sources of bias throughout the microbio...
Precise and fast spectral FLIM at video rate in confocal from 2018-06-26T17:00
Förster (Fluorescence) Resonance Energy Transfer (FRET) has become a powerful tool to study protein-protein interactions and signal transduction in living cells. FRET is commonly read out either by...
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Complete and Fast 3D Image Analysis in Microscopy from 2018-05-29T17:15
If image analysis is a place you fear to tread, or if you struggle with over complicated and time-consuming microscopy image analysis workflows, this is your opportunity to go beyond those limits.<...
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A Guide to Harnessing DNA Assembly for Drug Discovery from 2018-05-15T16:45
Current DNA synthesis and assembly technologies give today's genetic engineers unprecedented freedom to control every aspect of genetic design. In this webinar on DNA assembly, you will learn:
...
Get the Best Microscopy Images with Huygens Batch Express from 2018-04-24T17:30
In this webinar, you will learn about the advantages of deconvolving all your images fully automatically. Discussed in this webinar:
- How to improve the quality of your images with the ne...
LASSO Probes for Massively Multiplexed Cloning from 2018-04-17T16:00
In this webinar, you will learn how to solve a major problem in creating expression libraries from genome sequences for downstream analyses. Specifically, you will learn:
- The difference ...
2D Superresolution for ZEISS Airyscan with 120 nm resolution from 2017-12-11T18:00
Utilizing a pinhole-plane imaging concept, ZEISS Airyscan allows for simultaneous improvement in resolution and signal-to-noise by capitalizing on an innovative 32-channel GaAsP photomultiplier tub...
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Designing Flanking Homology DNA Assembly Experiments from 2017-11-15T17:45
Join us in this webinar on demystifying DNA assembly. In this webinar, you will learn:
- How flanking homology DNA assembly methods work
- How to use web-based software to design exper...
Biological Applications of XRM and Correlative XRM – FIB-SEM from 2017-11-08T17:45
In this webinar, you will learn about the power of 3D imaging of larger samples. In particular, you will:
- Gain insight in to how to use x-ray microscopy to analyze biological samples
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Large Volume Serial Blockface Electron Microscopy Imaging from 2017-09-08T17:00
An unlikely renaissance is occurring in biological imaging, propelled by the ongoing development of serial blockface electron microscopy imaging technologies. Imaging systems based on scanning EM i...
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Optocardiography: Optical Imaging of Cardiac Physiology from 2017-07-20T17:45
In this webinar, you will learn how to use optical imaging for functional cardiac physiological mapping of transmembrane potential, calcium handling, and metabolism.
The main aspects cover...
How to Conduct Localized Proteomics of Microscopic Regions from 2017-06-12T16:15
In this webinar, you will learn:
- How to perform isolated proteomics of microscopic regions of interest
- How to use this technique with FFPE tissue
- How proteomics can help you ...
Harnessing the Power of Heterogeneity in cryo-EM from 2017-06-07T16:15
A major impediment in the determination of high resolution protein structures by single particle cryo-electron microscopy has been the presence of sample heterogeneity. Oftentimes, heterogeneity is...
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Mouse Whole-Brain Volume Electron Microscopy for Cellular Co from 2017-05-16T22:36
Recent advances in high-throughput multi-beam scanning electron microscopy (EM) and mouse whole-brain EM preparation and collection on tape (“Brain-on-Tape”) have resulted in substantial progress t...
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Engineering Cell Behavior with Synthetic Biology from 2017-05-10T22:20
In this webinar, you will learn how synthetic biology can be used to engineer desirable and robust behaviors or traits into model organisms.
The main aspects to be covered in this webinar ...
Development of a Potential Recombinant Protein Vaccine in E. from 2017-05-03T22:07
Recombinant proteins can be powerful stimulators of the immune system making them good candidates for vaccines. Using the intracellular parasite, Leishmania donovani as an example, this webinar wil...
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Guide to CRISPR/Cas9 Delivery: How to Maximize Your Editing from 2017-04-18T22:30
In this webinar, you will learn how to maximize your genome editing efficiency using CRISPR/Cas9 and how to apply this technique in your research.
The main points in the webinar will inclu...
Multiplex PCR Technology: What Is It All About? from 2016-12-01T17:30
Join Dr. Karen Oâ??Hanlon Cohrt for a practical tour of multiplex PCR technology, where you will learn the following and much more:
Principle behind multiplex PCR technology
Popular ap...
Open Access: Facts, Myths, and Effects on Your Research Fund from 2016-10-25T17:30
The rise of open access is changing how research is communicated. In this webinar, we’ll celebrate Open Access Week 2016 by taking a closer look at how open access affects how researchers write and...
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Color Image Quality Control in Microscopy from 2016-09-29T20:09
In this webinar, Mark Clymer discusses color reproduction in microscopy images—and how to fix it if your color reproduction goes awry.
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Incorporating New Dyes to Simplify Panel Design - Reagent from 2016-09-28T17:30
Incorporating New Dyes to Simplify Panel Design: Accelerating Reagent Availability
In this webinar you will learn how custom reagents can aid you in flow cytometry panel design—without lon...
Decoding Cancer: Practical Advice for Working with Cellular from 2016-08-09T21:00
In this webinar, Dr. Ania Wronski discusses the process for genotyping cells—particularly tumor cells—and practical advice for analyzing the resulting data.
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All about miRNAs: Practical Tips, Advice, and Applications from 2016-07-22T19:46:47
Dr. Brian Adams is a researcher on the leading edge of miRNA research. Join him in this webinar as he demystifies working with miRNAs and gives you his best tips and tricks for working with them in...
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Tools for Analyzing Genetic Variants from Sequencing Data from 2016-06-21T17:17:33
Every individual harbors millions of genetic variants, many of which may contribute to phenotype. As the cost of sequencing has plummeted, we now have the opportunity to profile this variation acro...
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5 Actionable Steps for Transitioning to a Non-faculty Career from 2016-06-17T18:33:24
The current state of the academic job market has come under scrutiny in recent years, largely because of the shrinking number of tenure-track jobs available. This situation has forced graduate stud...
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Next-Generation Sequencing Overview: Step By Step Guide from 2016-06-17T18:28:35
Next generation sequencing (NGS) is a powerful tool for investigating genome-wide phenomena. It has been used to study epigenetic profiles as part of the ENCODE project. It is being used to underst...
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How Bitesize Bio Gets Progressive Companies to Help You from 2016-06-17T17:57:47
Whether it’s equipment costing hundreds of thousands of dollars and requiring millions of dollars in R&D investments or standardized kits that relieve you of tedious grunt work day in and day out, ...
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Using FIT probes and Super-Resolution Microscopy from 2016-06-17T17:53:47
For more information, please visit: http://bitesizebio.com/webinar/25961/deciphering-steps-of-mrnp-assembly-in-developing-oocytes-using-super-resolution-microscopy/
All mRNA molecules recr...
Know the Players: Combinatorial, Single-Cell Approaches from 2016-06-17T17:46:14
We know that cellular heterogeneity in the tumor microenvironment complicates the diagnosis and treatment of cancer. Tumors are complex, dynamic systems composed of diverse cell types in various fu...
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Critical Success Factors for Sample Collection from 2016-06-17T17:35:25
Biobanks, or biorepositories, store biological samples that are critical for research in the biomedical fields. Samples from biobanks have been used for genomics research, investigations into the d...
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Laser Microdissection – Dissection Perfection from 2016-06-17T17:33:44
Leica Microsystems Laser Microdissection systems are the method of choice for laser-based microscopic sample dissection and collection. Laser Microdissection (LMD) is a microscopic technique for is...
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How To Be Happier and More Productive in Your Work from 2016-06-17T16:41:08
Enjoying your work should be one of life’s top priorities not only because you spend much of your time working, but also because if you enjoy your work you’ll inevitably do a better job.
H...
Getting Correct Color from Your Camera from 2016-06-15T20:51:31
Seeing and believing that the dress is yellow may not be that important for the casual wedding image, but in microscopy imaging seeing and believing is critical. Microscopy images that contain colo...
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Combining Light Sheet & Confocal Microscopy from 2016-06-15T18:27:29
Living cells and organisms often suffer from the high light intensities that are used in conventional imaging. Light sheet microscopy reduces phototoxic effects and bleaching, by only illuminating ...
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qPCR Tips: Workflow, Applications and Troubleshooting from 2016-06-09T17:30
In this webinar, you’ll get:
Practical advice for sample preparation, qPCR setup and result analyses
Guidance on choosing the correct fluorescent labeling system for your qPCR
Tips...
Liquid Biopsy Sample Handling from 2016-06-08T19:29:07
Recently, there has been a push to develop alternative methods to traditional invasive techniques, such as solid tissue biopsies, for disease diagnosis and disease progression, as well as therapeut...
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Fast Module for ZEISS LSM 880 with Airyscan: Superresolution from 2016-05-31T17:30
The Fast Module for ZEISS LSM 880 with Airyscan: Confocal Superresolution Imaging with Four Times the Speed and Improved Signal-to-Noise Ratio
First introduced in August 2014, the Airyscan...
Optimizing ChIP for Reproducibility from 2014-07-23T16:45
Chromatin Immunoprecipitation (ChIP) is a powerful technique for evaluating the interactions of proteins with specific regions of genomic DNA, helping to better understand the mechanisms such as, g...
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