Podcasts by Plenary Session
A podcast on medicine, oncology,
Further podcasts by Vinay Prasad, MD MPH
Podcast on the topic Wissenschaft
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COVID19 Policy: What the US Got Wrong from 2023-11-26T01:22
My Lecture in Curacao 4/4 Vaccines, Masks, Mandates, Lockdowns, School closureOther lectures to come
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Lecture 1 of 4 Curacao - How to Keep Up with Literature from 2023-11-24T22:09:54
Entresto, Lung Transplants, How to Keep Up with Literature - Lecture to Trainees in Curacao
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Advice Pre-Med Students | Lecture at UC Berkeley from 2023-11-11T01:43:10
This is a lecture I gave on November 5, 2023, to pre-medicine undergraduate students at University of California Berkeley.
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Radiation oncology in GI malignancy - Nina Sanford and Bill Hall from 2023-10-31T18:15:25
Radiation oncology in GI malignancy (endpoints and stratification) in the JCO
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Hawai Keynote - Coffee and colon cancer&Censoring&More from 2023-10-23T01:25:52
Prasad is back in Hawaii to give another keynote (good thing they cancelled Dallas not Honolulu). I discuss coffee and colon cancer, and censoring, and Lu177 PSMA
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Ethics: How IRBs Can Do Better | My Denmark Lectures (Sept 2023) 3 Of 3 from 2023-10-19T18:15:33
This is a lecture I gave on ethics and institutional review boards in Denmark in September 2023. It is the last of the three lectures I gave.
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Prasad's lecture gets cancelled/ Cifu Gets COVID a SM crossover from 2023-10-16T15:01:41
Mandrola, Prasad and Cifu are back to discuss the latest drama
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The State Of Immunotherapy In Oncology | My Denmark Lectures (Sept 2023) 2 Of 3 from 2023-10-09T04:27:06
This is a lecture I gave on the state of immunotherapy in oncology at the Immunotherapy Symposium In Denmark in September 2023. It is the second of three lectures I gave.
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Do We Have Good Evidence For New Drugs? My Denmark Lectures (Sept 2023) 1 Of 3 from 2023-10-04T01:56:12
The first of the three lectures I gave in Denmark in September 2023 was on the medical evidence behind decision-making by health technology assessment groups.
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Great And Crazy Things We Do In Medicine from 2023-09-20T03:50
This is the live recording of a talk given on the great and crazy things we do in medicine, from cancer drugs to boosters and more.
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Fixing Cancer Medicine w/ Timothee Olivier from 2023-09-12T16:02:44
Timothee is back to discuss Malignant and Solutions
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Coumadin, ECMO, RCTs and more from 2023-09-11T00:51:48
A far reaching discussion btw Mandrola and Prasad on RCTs, Coumadin, ECMO and RCTs for covid shots
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Prasad and Mandrola discuss recent journal articles/ Republicans/ Stenting from 2023-08-23T01:35:58
Simultaneously released on Sensible Medicine. Time to subscribe to Sensible Medicine substack and podcast.
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Placebo/ Journal Errors/ Cancer Screening w/ Mandrola - SM crossover from 2023-07-10T16:50:53
Placebo/ Journal Errors/ Cancer Screening w/ Mandrola - SM crossover
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Testosterone/ Should Scientists Debate/ Mike Joyner from 2023-06-28T00:50:38
A sensible medicine crossover episode Follow the sensible medicine podcast feed for more of these discussions
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Post Protocol Therapy - QOL - Adjuvant - Olivier Joins VP from 2023-06-10T01:58:33
T. Olivier from Geneva is back. A fan favorite guest. We discuss 3 recent papers.
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ADAURA OS RESULTS - THE TRIAL WAS UNETHICAL from 2023-06-08T20:24:35
Researchers were too busy counting dead bodies to give the control arm appropriate therapy when their cancer recurred. Disgusting conduct. I break down ADAURA
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OBS studies vs RCTs - Trial Emulation - RCT Duplicate - We debate recent JAMA Paper from 2023-05-17T23:26:47
Mike Putman, Todd C. Lee, John Mandrola and I debate the recent JAMA paper on RCT Duplicate. This is a spirited round table discussion on the limitations of observational data. If you are reading...
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Myeloma Roundtable - Manni M. Raj C. VP discuss controversies from 2023-05-13T20:45:19
Early treatment of myeloma, dual vs. single maintenance, and finally transplant or no transplant.
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Mammographic Screening : A complete review of the evidence from 2023-05-11T03:23:32
Why the USPSTF is wrong
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The Crushing, Cruel Cost of Cancer Drugs - My Lecture from 2023-04-29T23:53:27
Cost of Cancer drugs - VP's lecture
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Sensible Med Crossover - Cifu/ Mandrola/ Prasad&Wallensky from 2023-04-24T04:45:40
I combine two latest tracks on interpreting medical studies, medical boards, 7 doses of vaccine, and finally Walensky. Stay tuned.
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Cochrane Mask Debates - Jefferson/ Heneghan/ Prasad from 2023-04-15T00:50:34
We explore the fight btw NYTimes, Cochrane, and the last people keeping EBM alive
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Zeb Jamrozik - Vaccine errors/ Sweden/ Equipoise&Science itself from 2023-04-12T04:19:51
Zeb joins me for the 7th time to discuss all the key pandemic questions
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Harvard-MIT Center for Reg. Science Lecture (4-4-23) - Dubious FDA drug Approvals from 2023-04-05T03:52:24
My lecture to Harvard regulatory science
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5.47 - Real World Evidence - Keynote Lecture in Denmark from 2023-03-26T08:25:03
VP goes to Denmark to give the keynote at the Danish medical association conference
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5.45 - Bar Karmma - Karmma 3 | Idacel vs 'standard care from 2023-03-07T05:20:43
Karmma 3 discussion; then Sensible Medicine on Long COVID, 4th year fellowships and more; Then my breakdown of FDA's NEJM Letter to the Editor
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More basics on randomized controlled trials - Part 2 from 2023-03-02T22:07:20
I get into endpoints, surrogates, validation, blinding, crossover, and control arms.
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RCT 101 And Papa Heme from 2023-02-28T01:40:22
I talk RCTs 101; KM Plots; Blinding: 2:1 randomization: Concealment and more. Then Papa Heme Tells you How to Find your First Job
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Tom Newman And VP Discuss Public Health from 2023-02-22T01:44:47
Dr. Tom Newman UCSF Emeritus Professor&Superb teacher discusses VP's recent Public Health Videos. The two don't fully agree, but the discussion is worth your time.
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5.41 - Michael Putman MCW debates me on recent policy Qs from 2023-02-16T22:46:58
Mike Putman, asst prof. EBM Rhematologist debates me on value of boosters, observational studies and more.
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Sensible Med Superbowl Plenary Session Crossover from 2023-02-13T16:15:17
A new podcast feed called Sensible Medicine is up; here is a sample of what we have to offer
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5.39 - Sotorasib and Codebreak 200 from 2023-02-10T01:40:52
I destroy the trial. Bad control arm. Informative Censoring. No OS gain. Authors DOWNPOWERED TRIAL. Fishy PFS. Fishy HRQoL. This trial should be in trash can.
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Myeloma Twitter Just Makes Things Up - Lessons for All Oncologists&Expertise from 2023-01-22T19:31:58
I annotate an online case discussion; Every decision is not based in evidence. Madness
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5.37 - Keynote Lecture on Physician Burnout from 2023-01-15T22:43:54
This lecture on Burnout will not be like any other you have heard
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5.36 - ASH UPDATE #4 - GEM CESAR from 2022-12-30T02:30:20
I break down the GEM CESAR trial K, R, D, Pom, Dara, Dex, R, and Auto and all before you actually have cancerWhat a crazy trial!
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5.35 - ASH Update #3 - the Ascent Trial from 2022-12-29T00:21:53
This uncontrolled trial of Dara-KRD claims to be looking for cure; Unfortunately, the PI has not thought through what that would look like, and accordingly all the claims are incorrect. Moreover th...
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5.34 - ASH Update #2 - ALPINE - Zanibrutinib vs Ibrutinib - Deconstructed from 2022-12-24T23:55:43
Sample size games, primary endpoint, head to head trials in oncology Rate this podcast on itunesComing next is Triangle trial
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5.33 USC Grand Rounds Hematology from 2022-12-23T21:30:13
Grand rounds on heme and heme malignancies given 12/16 at University of Southern California (some parts removed) More ASH coming soon
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5.32 - ASH Update #1 - Talquetamab NEJM from 2022-12-11T19:39:33
Is it acceptable to take someone with myeloma who has gotten just 2 regimens and put them on a phase 1? VP says hell no.
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5.31 - MUST LISTEN Grand Rounds - COVID19 Updates from 2022-12-08T18:59:34
In this lecture given December 7, 2022, I cover 5 things: VaccinesMasking Long COVIDSchools/Immunity Debt Paxlovid
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5.30 Rajkumar vs Goodman; Long COVID vs Long URI from 2022-12-03T20:19:38
Should we treat smoldering MM, a debate Long COVID vs Long URIReview the show; Say Hi at ASH22
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5.29 Smart Start is a useless Lymphoma study from 2022-11-27T01:13:09
Smart Start is a useless lymphoma study; We have to stop putting our careers ahead of patients. In the second part, I discuss the 'experts' featured on STAT. Wowzers. I will be at ask. Hit me up...
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5.28 - Pandemic Amnesty or Accountability with Paul Fenyves from 2022-11-12T03:26:32
I am joined by Cornell Professor Paul Fenyves; a practicing internist Dr. Fenyves walks us through COVID19 policy. We will be back soon with more cancer medicine. Including a devastating lymphoma ...
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5.27 - Multiple Myeloma - Do Our Trials Help Patients? from 2022-11-08T21:24:32
I was invited to give this talk to a UK conference on Myeloma Please LEAVE A REVIEW of this podcast
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5.26 - Hawaii Oncology Association Keynote Lecture from 2022-11-06T16:12:12
Lecture I gave this weekend in Hawaii to the Medical Oncology Association; One of the best audiences I've had
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5.25 - Neurosurgery Grand Rounds by Vinay Prasad from 2022-11-03T04:36:19
I give Grand Rounds to UCSF Neurosurgery on how to read and interpret Neurosurgery Studies (Video and slides coming soon to YouTube)Also I discuss Bob Califf's Promotion of Paxlovid
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5.24 Vlad Kogan is back to discuss Kids Test Scores from 2022-11-01T14:25:14
Learning Loss is Devastating; Here are the data and what it means
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5.24 - Gerald Hsu MD PhD UCSF Heme Onc Program Director from 2022-10-28T03:02:05
Learn about UCSF Hematology Oncology Program with Dr. Gerald Hsu, MD PhD Malignant Heme and Program Director
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5.23 - Subclinical Myocarditis from 2022-10-19T23:30:23
A new study from Switzerland confirms the rate of subclinical myocarditis
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5.23 - ID Ethicist joins me for a 6th discussion of COVID19 policy from 2022-10-18T16:07:46
LONG COVID, Vaccines, Paxlovid and More
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5.22 NordICC trial interview with PI Michael Bretthauer - Offer but don't Nudge from 2022-10-15T00:59:25
discuss NordICC with the trial PI Power calc specified 50% non-adherenceADR is on par with US studies from the time Colo quality goodPerf rate lower than US! How does he counsel individuals&governm...
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5.21 Science Mag Editor Condemns Ladapo But Silent About Jha from 2022-10-14T03:19:40
A double standard to condemn data with limitations, based on political party, will destroy medicine. We will back to oncology soon, but this is important
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5.20 The Great Colonoscopy Debate from 2022-10-11T18:00:18
Cifu, Mandrola and Prasad fight about colonoscopy
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5.19 - NEJM's first ever RCT of Colonoscopy-- Explained from 2022-10-09T22:23:11
I break down the history and data for the first ever randomized trial of colonoscopy, appearing in NEJM on Oct 9, 2022
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5.18 Lecture to Heme Onc Fellows - POLO; Javelin 100 bladder from 2022-10-08T15:39:10
Polo Javelin 100 bladder Crossover Control arms How to read and keep up with the literature
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5.17 - The State Of Precision Oncology from 2022-10-07T00:48:15
Invited Lecture to Cancer Center Directors
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5.16 - Aaron Goodman UCSD from 2022-09-29T19:54:51
I travel to UCSD to interview Dr. Goodman about myeloma, celebrity oncology culture, his career, education, patient care, choosing a specialty and more.
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5.15 - How To Apply For And Get Your Perfect First Job from 2022-09-21T21:40:55
Based on listener questions, I discuss how to apply for and get your first job.
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Unspoken Rules of Oncology - Malignant BC Part 6 from 2022-09-18T00:21:24
T.O. joins me for the missing episode. These are the unspoken rules of Oncology; We dive deeper into Malignant Book Club.
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Malignant Book Club - Episode 7 - famous trials from 2022-09-09T16:28:05
Timothee Olivier joins me for the 7th installment of our book-club We cover famous trials in oncology
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5.12 - Academics Vs Industry - A.Goodman S.Loghavi D.Steensma V.P. from 2022-09-03T01:35:44
How do careers vary between the academy and industry? We have a panel of the best: Sanam Loghavi from MD Anderson, Aaron Goodman UCSD, and David Steensma Novartis (formerly Farber/ Mayo) and VP #...
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5.11 - Malignant Book Club - Part 5 from 2022-08-26T00:38:01
Timothee Olivier joinrs me as we explore part 3 of the book Crossover, sample size, observational vs RCTs
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5.10 - Adam Cifu on clinical excellence from 2022-08-24T15:57:14
Adam Cifu is here to discuss clinical excellence and his new podcast
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5.09 - Malignant Book Club Part 4 from 2022-08-22T00:25:32
T.O. joins me to grill me on the rest of Financial Conflict of Interest and Precision Oncology. We discuss the need for randomization, and when it can be omitted. A must listen for Oncology Fans.
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5.08 - LaceWing RCT Phase 3 Blood - Spin Cycle from 2022-08-18T16:44:28
VP discusses the LaceWing study in Blood. A Phase 3 RCT of GILT AZA vs AZA; Medical writers; confounding; table 1; balance; and so much more
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5.07 - Plenary Session Alps Edition from 2022-08-10T06:36:48
Timothee Olivier joins me to discuss recent papers: IMPOWER10Checkmate 816 Path CR/ EFS/ SurrogatesDrug Dosing, cGCSF rules and more Bread and butter oncology
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5.06 - POLO trial now has OS results - OMG from 2022-07-21T01:03:49
The POLO trial, which we first broke on PS Season 1- is back with null OS results. But the trial authors enter the spin cycle. VP goes line by line.
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5.05 - Citations, Metrics, Rankings in Oncology&Medicine from 2022-07-18T05:38:19
VP explains H index, total cites, papers, US News and World Report rankings and how evaluates researchers and doctors.
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5.04 - Echelon 1 reports OS benefit - But does it add up? from 2022-07-14T23:54:59
VP addresses what to do you if you get an idea from listening to the show, and deconstructs ECHELON-1. Instead of listening we highly recommend you watch the video on YouTube with graphics. This i...
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5.03 - VPs Grand Rounds Lecture - Evidence Based Medicine - Will it Survive? from 2022-07-13T04:59:47
How to think about when and how to do RCTs? What are the limitations to observational studies? Smoking. Parachutes. Dostarlimab. Guarantee Time Bias. Confounding. Multiple Hypothesis testing and ...
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5.02 - Listener Questions - Cancer&Evidence Philosophy - What this Pod Offers from 2022-07-11T01:27:24
I make the case why this podcast should be your go to for Med, Onc&Policy. I describe my philosophy of Evidence, Empiricism, and show how this connects to many oncology studies. I answer a bunch ...
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5.01 - How To Read Randomized Trials In Cancer from 2022-07-07T23:58:45
How to read randomized trials in cancer medicine. Phase 2 vs 3, control arm, crossover, post protocol, censoring (the basics), and how law professors and medical professors are different and why it...
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Lies and Exaggerations about Kids Vaccines<5 years Old is Bad Public Health from 2022-06-22T05:31:10
Lies and Exaggerations about Kids Vaccine I give examples, and show why they are lies
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Enact Trial - Enza vs Active Surveillance in Localized Prostate Cancer from 2022-06-20T14:19:40
What happens when you treat people with $168,000 a year medicine when most of them will never need treatment, and all of them don't need treatment now
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Kids Vaccine For Under 5 years Old from 2022-06-18T22:56:55
I take a deep dive into the data for the mRNA vaccines for kids under 5 years olds
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H. Jack West; Lung Cancer; Podcasting; TeleHealth: PACIFIC; ADAURA;CM816: KN189 from 2022-06-18T02:54:06
I sit down with H Jack West. City of Hope. Thoracic Oncology and we have a long discussion about trials; staging; PDL1 thresholds; Driver mutations and post protocol care; ADAURA; Adjuvant;&More
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QuANTUM - Quizartinib Front Line - Ethics of Global Trials from 2022-06-15T13:16:33
I discuss the timeline of Ratify and Quantum. Was this an ethical trial? Is it sufficient to say a trial is ethical because 50% of participants get something?
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4.67 Teclistimab for R/R Multiple Myeloma from 2022-06-09T22:56:25
The drug has a high response rate and lots of infections, is it active? Yes; Efficacious? ???? I review ASCO2022 updates
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4.66 PD1 Ab for MSI H Stage II/ III Rectal Cancer; A 100% CR rate?? from 2022-06-08T14:23:41
Are the results from Luis Diaz as good as touted. What trial should they do going forward? A 100% CR rate in Stage II and III rectal cancer??
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4.65 DESTINY BREAST 04 - A complex trial to deconstruct from 2022-06-07T14:25:07
My take on the standing ovation for DESTINY Breast 04 Traztuzumab Deruxtecan vs. Investigator choice after endocrine therapy and 1 or 2 chemotherapies for HER2 low
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4.64 - DETERMINATION - Should we still use transplant Myeloma? from 2022-06-06T14:52:57
I break down Richardson, et al. NEJM DETERMINATION Transplanters are determined to keep going, should they be?Watch the videos b/c I have lots of great visuals My ASCO Coverage continues
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4.63 - ASCO22 - DYNAMIC - Can CT DNA Allow us to Give Less Chemo in Stage II Colon Cancer from 2022-06-05T23:14:58
The second paper from #ASCO2022 #ASCO22 that I break down This is one of the most technical papers I breakdown on the channelCT DNA used to omit chemo in Stage II colon cancer Read the book Maligna...
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4.62 - SHINE - Ibrutinib BR vs BR; Limitations to the trial from 2022-06-04T19:33:26
Continuous vs. Fixed, 3 vs 2, PFS is the primary endpoint No OSBad crossover Lots to discuss hereI will be covering all the major ASCO papers on @PlenarySession Subscribe to my substack https://vin...
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4.61 - How CDC's Vaccine Safety Missed Cases Of Myocarditis from 2022-05-27T00:43:24
I am joined by Dr. Katie Sharff, infectious disease doc, to discuss two of her papers on myocarditis after COVID-19 vaccination. https://doi.org/10.1016/j.amjcard.2022.02.039https://doi.org/10.110...
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4.60 - NEW JCO paper - AML, EFS, CR, CRi, and Surrogate validation - FDA&Methods from 2022-05-21T18:09:05
I get back to my roots; I explain surrogate validation and a new JCO paper from the FDA authors on EFS and OS in AML. You won't want to miss it
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4.59 - How to be a better reader of case control studies from 2022-05-17T04:06:02
In this episode I dissect a test negative case control trial; I talk about a famous pancreas cancer study and I revisit the failure of Myeloma trialists
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4.58 - Myeloma is a broken field - New BLOOD Paper! from 2022-05-14T18:19:03
I am joined by Manni Mohyuddin to talk about How I treat frontline transplant eligible myeloma. Vinay Prasad makes the case the entire field of myeloma is corrupt and broken.
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4.57 - COVID19 and the Failures of Public Health w/ Leslie Bienen from 2022-05-06T17:48:48
I join Dr. Bienen in person to discuss COVID19 and failures in public health
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4.56 - Fifth Installment of the brilliant Zeb Jamrozik from 2022-05-04T01:30:07
ID ethicist, and brilliant COVID19 commenter
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4.55 - Compilation Of Recent Covid Monologues from 2022-05-01T04:21:20
This is a compilation of the last week and half of monologues by VP on his Youtube Channel about COVID19 policy
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4.54 - Eric Collisson Professor, GI Oncologist, Physician Scientist from 2022-04-30T01:35:02
I talk to UCSF Professor Eric Collison about his lab, grant writing, the physician scientist life, cancer, and a doctors duty.
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4.53 John Ioannidis lectures the VKPrasad Lab about COVID19 from 2022-04-27T19:02:35
A brilliant talk by one of the most brilliant scientists alive; JPAI lectures VKPrasad lab on all things COVID19; When does the pandemic end? What are the lessons?
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4.52 Vinay Prasad Gives a Lecture on COVID19 to a General Audience from 2022-04-24T16:09:12
Listen in as I give an unscripted lecture to a general audience about COVID-19; What we got right and wrong these last 2+ years.
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4.51 - Vinay Prasad is Interviewed by Kristina Jenei About Academic Medicine from 2022-04-22T03:24:28
Kristina Jenei becomes the 4th guest host and flips the tables on me, interviewing me about academic medicine and more...
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4.50 - Ivosidenib&Aza vs Aza, the AGILE, 6 huge problems; Journal club from 2022-04-21T06:32:48
I perform an analysis of the AGILE trial that came out in NEJM today; I find 6 huge problems. Follow PS on twitter; and write to us to let us know what you think
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4.49 - Malignant Book Club Part 3 Audio from 2022-04-15T03:47:51
Timothee Olivier joins me for the 3rd of 9 parts of the Malignant book club - this covers all of Oncology
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4.48 - The Truth About RCTs In Cancer Medicine from 2022-04-07T21:13:36
Pragmatic vs Ideal, Surrogate vs. Hard Endpoints; Time it takes; Ethics; Control arms; Purpose; I cover it all here.
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4.47 Malignant Book Club w/ Dr. Olivier Part 2 of 9 from 2022-03-22T00:24:02
In this book club we discuss Chapters 2 and 3 of Malignant, covering Surrogates and their role in Oncology
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4.46 - Cancer Monologue and Lecture #5 from VP's Class on How to Appraise Medical Literature from 2022-03-16T23:19:43
This is a brief monologue with Dr. Timothee Olivier, and the audio from a class I taught on RCTs-- when are they needed in biomedicine
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4.45 - Malignant Book Club w/ Dr. Olivier Part 1 of 9 from 2022-03-12T00:42:50
Here is the first of a 9 part series on Malignant Book Club with Timothee Olivier from Switzerland We cover cost of drugs, and intro to cancer drug policy
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4.44 - Cost Of Cancer Drugs - Basics In Cancer Drug Policy from 2022-03-04T01:02:25
I lecture on basics on cancer drug policy
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4.43 - VKPrasad Lab Update Part 2 With Timothee Olivier from 2022-03-01T00:11:22
I am back with Timothee Olivier from Geneva Switzerland to discuss Part 2 of our laboratory work. Can oncologists criticize RCTs? We also announce our new series. A 9 week Malignant Bookclub
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4.42 - Timothee Olivier, Geneva in the first Installment of VKPrasad Lab updates from 2022-02-24T20:18:31
Timothee Olivier from Geneva Hospital Switzerland joins me for the first in a series of episodes on updates from VKPrasad laboratory, where we discuss cancer drugs&policy&evidence
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4.41 The Mask Debacle with Jacob Hale Russell from 2022-02-19T01:40:39
Jacob Hale Russell is back from Rutgers law to talk about his new piece in Tablet Magazine.
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4.40 H Gilbert Welch - Melanoma Screening; Blood Based Cancer testing; Lung CA screening from 2022-01-28T15:47:24
A discussion about the excesses of testing with Gil Welch
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4.39 Dr Zeb Jamrozik, ID ethicist, practicing doctor, great thinker from 2022-01-27T01:51:43
I am joined for my 4th conversation with Zeb. This is a far reaching conversation where we discuss mandates, vaccines, masking, and why evidence based medicine still has something to offer.
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4.38 COVID-19: Boosters for Adults and Teens, Paul Offitt, Testing, Myocarditis, Campus Restrictions from 2022-01-21T03:05:35
We're back this week with a collection of monologues! We talk about a Paul Offitt quote, COVID boosters for adults and kids, COVID testing, whether this is a pandemic of the unvaccinated, myocardit...
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4.37 MEMOIR&The Emperor Has No Clothes (a Critique of Cancer Care) with Dr. Christopher Booth from 2022-01-06T22:22:51
Today we have a short discussion for you of the MEMOIR study, published in The Lancet Oncology: "Effect of immunotherapy time-of-day infusion on overall survival among patients with advanced melano...
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4.36 Where Are We Now with COVID-19? with Dr. John Ioannidis from 2022-01-04T20:00:02
Today we have an in-depth, in-person interview with Dr. John Ioannidis of Stanford University. We ask him: where are we now with COVID-19? Back us on Patreon! www.patreon.com/plenarysessionCheck o...
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4.35 Omicron, Travel Bans, Masks, Vaccine Mandates with Dr. Zeb Jamrozik from 2021-12-31T22:19
Dr. Zeb Jamrozik, an infectious disease bioethicist at the Monash Bioethics Centre and the University of Oxford, is back again! We discuss Omicron, travel bans, masks, vaccine mandates, and more. ...
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4.34 ASH Lymphoma Updates: POLARIX, ZUMA 7, BELINDA w/ Papa Heme and DRG from 2021-12-24T16:54:22
David Russler-Germain and Papa Heme join VP to discuss the hottest ASH lymphoma papers: POLARIX and 2 CAR-T trials (ZUMA-7&BELINDA) Back us on Patreon! www.patreon.com/plenarysession Check out o...
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4.33 Melanoma: Tebentafusp, Stage Migration, Adjuvant Therapy, Training with Dr. Adil Daud from 2021-12-22T04:05:38
We have an in-person interview for you today! We sit down with Dr. Adil Daud of UCSF to talk all things melanoma. We cover Tebentafusp, nodal dissection, the Will Rogers phenomenon and the effect o...
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4.32 Oral Azacitidine for AML and Nelarabine for T-ALL with Dr. Bernard Marini from 2021-12-03T03:47:53
We're back with a hematology/oncology heavy episode! We talk about oral azacitidine for acute myeloid leukemia (AML) and nelarabine for T-cell acute lymphoblastic leukemia (T-ALL) with Dr. Bernie M...
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4.31 Neoadjuvant Radiation Therapy in Pancreatic Adenocarcinoma with Dr. William Hall from 2021-11-24T20:00:19
Today we interview Dr. Bill Hall, Associate Professor of Radiation Oncology and Surgery at Medical College of Wisconsin, on his new paper out now in the Journal of Clinical Oncology titled "Value o...
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4.30 COVID in Children and the US FDA Vaccine Advisory Committee with Dr. Cody Meissner from 2021-11-22T04:26:14
Today we interview Dr. Cody Meissner, Chief of the Division of Pediatric Infectious Disease and Professor of Pediatrics at Tufts University School of Medicine. Dr. Meissner is also a member of the ...
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4.29 Scientific and Ethical Failures of COVID-19 with Dr. Zeb Jamrozik from 2021-11-11T01:23:28
Dr. Zeb Jamrozik, an infectious disease bioethicist at the Monash Bioethics Centre and the University of Oxford, is back by popular demand! We talk about the failures, both scientific and ethical, ...
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4.28 Calling Out Unethical Clinical Trials, Melflufen, and Academic Oncology with Dr. Aaron Goodman from 2021-11-06T04:48:09
We're joined today by Dr. Aaron Goodman, a hematologist/oncologist at the University of California San Diego, to talk about calling out an unethical clinical trial, Melflufen, and academic oncology...
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4.27 Economics and Medicine with the Host of Freakonomics, M.D., Dr. Anupam Bapu Jena from 2021-10-29T21:01:58
We're joined by Dr. Bapu Jena of Harvard Medical School to talk about his show, Freakonomics, M.D., and his career at the intersection of economics and medicine. Back us on Patreon! www.patreon.co...
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4.26 Recent Kidney Cancer Trials, Unethical Cancer Clinical Trial,&CASSIOPEIA from 2021-10-28T04:06:19
We have three topics for you today: We talk about our recent paper on the use of second-line immunotherapy in kidney cancer, the controversy over whether a cancer clinical trial was unethical, and ...
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4.25 A Critique of COVID-19 Health Policy with Infectious Disease Ethicist Dr. Zeb Jamrozik from 2021-10-20T00:58:53
Today we have an interview with Dr. Zeb Jamrozik, an infectious disease bioethicist at the Monash Bioethics Centre and the University of Oxford. We talk about COVID-19 health policy and where we we...
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4.24 COVID-19: Moderna booster, Myocarditis, Progressivism, Social Media, Masks, Tests, J&J booster from 2021-10-16T03:31:05
We have a summary of our thoughts for you on recent news about COVID. We discuss the prospect of FDA authorization of a Moderna booster, 8 lessons for health policy in times of crisis, updates on m...
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4.23 Access to Cancer Medicines, Standard of Care in Oncology, and the Oncology Value Paradigm from 2021-10-15T03:23:13
On today's episode we're joined by a number of special guests: Dr. Christopher Booth and Dr. Adam Fundytus of Queen's University in Kingston, Ontario, Dr. Manju Sengar of the Tata Memorial Centre, ...
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4.22 Honoring Dr. Elilhu Estey and His Decades-Long Oncology Career from 2021-10-12T05:24:04
On today's episode, in honor of him and in recognition of his passing, we have an old interview with Dr. Elihu Estey of the University of Washington on his 40 years of experience as an oncologist, ...
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4.21 Cognitive Errors in Medical Decision-Making with Dr. Daniel Morgan&COVID-19 Policy from 2021-09-22T23:00:04
This week we take a break from #zercovid to give you another episode that's a deep dive into COVID-19. We start with an interview with epidemiologist and infectious disease expert Dr. Daniel Morgan...
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4.20 Vaccinating Kids and College Students, Boosters, Outdoor Masking, Bangladesh RCT,&more! from 2021-09-14T04:11:18
Today we take a brief break from our #zerocovid mantra to offer you our thoughts on current events. We cover a variety of topics, including: medical doctors in academia, cancelling conferences even...
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4.19 Censoring: Not on Facebook, but in Kaplan-Meier Curves from 2021-09-08T04:18:13
Today's episode is a lecture our host, Dr. Vinay Prasad of University of California San Francisco, gave recently on censoring patients in Kaplan-Meier plots. Back us on Patreon! www.patreon.com/pl...
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4.18 Dementia Interventions, Skills for Epidemiologists,&Aducanumab with Dr. Maria Glymour from 2021-09-01T02:10:38
Today we're joined by social epidemiologist, Dr. Maria Glymour of UCSF. We talk about her work in studying public health interventions for dementia and how her experience in academia has led to her...
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4.17 RCTs for Cancer Drug Approval with Dr. Saroj Niraula&Myeloma Studies with Dr. Manni Mohyuddin from 2021-08-27T04:42:47
We have two oncology conversations for you today. The first is with Dr. Saroj Niraula of the University of Manitoba, and together we discuss the necessity of randomized controlled trials for granti...
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4.16 Treating Lymphoma, Histiocytic Disorders, Learning by Teaching,&More! with Dr. Bita Fakhri from 2021-08-21T20:07:38
Today we interview Dr. Bita Fakhri of UCSF on the current research behind treatments for lymphoma. We touch on CAR-T, ABVD, DA-EPOCH-R, and more. We also talk about histiocytic disorders, Dr. Fakhr...
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4.15 #AllCOVID-19: the Tough Questions About Policies Concerning the Delta Variant of COVID-19 from 2021-08-19T03:04:11
Today we're compiling all our recent monologues on COVID-19. That's right -- we're taking a break from #zerocovid to give you an episode that's #allcovid! We cover a whole range of news and opinion...
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4.14 Evolution of GI Cancer Therapy, Editing JCO, Advice for Clinical Trialists with Dr. Alan Venook from 2021-08-11T19:40:55
Today we interview Dr. Alan Venook of UCSF, a renowned expert in clinical trial design and gastrointestinal malignancies. We talk about the evolution of the treatment for colorectal cancer over the...
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4.13 Lessons from Publishing 300 Peer-Reviewed Papers&What Telemedicine Will Do to Cancer Care from 2021-08-06T21:46:42
We have two short thinkpieces for you. The first is on the lessons that can be learned, or have been learned along the way, from publishing 300 peer-reviewed papers in medical/scientific journals. ...
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4.12 Real-World Survival Outcomes for Pertuzumab and T-DM1 with Dr. Josee-Lyne Ethier from 2021-08-03T22:42:38
Today we interview Dr. Josee-Lyne Ethier of Queen's University in Kingston, Ontario, Canada on her new paper "Practice Patterns and Outcomes of Novel Targeted Agents for the Treatment of ERBB2-Posi...
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4.11 CheckMate 274, PARADIGM-HF/Ernesto, POLO,&an AI Approach to Reducing Knee Pain from 2021-07-31T01:53:36
Today's episode is a compilation of a few short monologues. We provide an oncologist's evidence-based medicine perspective on four papers: CheckMate 274, adjuvant nivolumab in urothelial cancer; PA...
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4.10 A Deep Dive into CheckMate 649 with Dr. Jeffrey Bien from 2021-07-28T02:00:59
Today we sit down (in person!) with Dr. Jeff Bien of Stanford University to break down all the details -- from the methods to the statistical analysis to the conclusions -- of the CheckMate 649 tri...
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4.09 Problems with the VISION Trial&Stool Transplant Plus Nivo for Metastatic Melanoma from 2021-07-23T19:18:42
Today we have two short monologues for you on recent papers. The first, by popular request, is the problems with the VISION trial, which treated metastatic castration-resistant prostate cancer with...
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4.08 Implications for the Fate of Accelerated Approval from the ODAC Votes of April 2021 from 2021-07-16T23:20:50
In today's quick episode, we talk about our new paper out now in JAMA Network Open titled "The Oncologic Drugs Advisory Committee Votes of April 2021—Implications for the Fate of Accelerated Approv...
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4.07 Questions from a Medical Student with Emma Greenstreet and Dr. Vinay Prasad from 2021-07-09T22:19:51
We have a reverse episode for you today! Emma Greenstreet, a second-year medical student at UCSF, interviews our usual host, Dr. Vinay Prasad on why and how he chose hematology/oncology as a specia...
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4.06 CAR-T, Oncology RCTs, Social Media, Myeloma, and Career Decisions with Dr. Rahul Banerjee from 2021-07-08T18:54:09
We sat down in person with Dr. Rahul Banerjee, a BMT/CAR-T fellow at UCSF, to talk about all manner of topics including CAR-T, randomized trials in oncology (and, specifically, Dr. Banerjee's two r...
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4.05 Exodus from Academia and the Regretful FDA Approval of Aducanumab with Dr. Ameet Sarpatwari from 2021-07-07T02:03:13
Today we are joined by Dr. Ameet Sarpatwari of Harvard Medical School to discuss how so many great minds in oncology are leaving cancer research in academia for industry. We also talk about the evi...
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4.04 Treatment Algorithm for Follicular Lymphoma&Assessing RCTs from 2021-06-26T00:14:41
Today we have a short monologue for you on just a few topics: a treatment algorithm for follicular lymphoma and our host Dr. Prasad's new paper out now in the European Journal of Clinical Investiga...
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4.03 Multiple Myeloma, Productivity Metrics, and Field Changes in Oncology with Dr. Nina Shah from 2021-06-18T15:36:52
Today we're back with another real-life (non-virtual!) interview. We're joined by Dr. Nina Shah of UCSF to discuss her career and her work in mutiple myeloma as well as the complexities of advancin...
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4.02 The History of Breast Cancer Research and Treatment with Dr. George Sledge from 2021-06-15T02:28:58
Today we sit down with Dr. George Sledge of the Stanford University Medical Center to hear the story of his career and to discuss the history of breast cancer research and treatment. Back us on Pa...
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4.01 Highlights from the 2021 ASCO Annual Meeting from 2021-06-11T22:44:01
Today we're launching season 4 of Plenary Session! This season we're returning to our love of monologues. On today's episode we talk about highlights from the recent annual meeting of the American ...
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3.90 Redesigning Health Care, Overuse, Burnout, and COVID-19 Groupthink with Dr. Marty Makary from 2021-06-04T19:00:01
On today's episode, we interview Dr. Marty Makary of Johns Hopkins School of Medicine and Bloomberg School of Public Health on how he chose his path in medicine, how health care as it is in the Uni...
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3.89 How to Think About COVID-19 Policy with Rare Events and Declining Probabilities from 2021-06-03T19:00:01
Today we have a brief monologue for you on how to think about COVID-19 policy in the context of rare event and declining probabilities. We also touch on what to expect from season 4 of this podcast...
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3.88 Behind the Scenes for the One-Year Anniversary of Malignant with Dr. Vinay Prasad from 2021-06-02T19:00:01
Today's episode is hosted by guest Logan Powell, an incoming medical student at the Texas A&M College of Medicine and creator of this podcast's show notes. He reverse interviews our usual host, Dr....
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3.87 Round Table on Multiple Myeloma Initial Therapy, High Risk, and Maintenance from 2021-05-31T19:00:03
Today we try something new. We're joined by five esteemed multiple myeloma experts for a back-and-forth round table discussion on the disease, including initial therapy, high risk, and maintenance....
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3.86 Lenvatinib plus Pembrolizumab or Everolimus for Advanced RCC with Dr. Karine Tawagi from 2021-05-28T19:00:03
Today we bring back our popular Journal Club with a Fellow segment. We're joined by Dr. Karine Tawagi of the Oschner Clinic in Louisiana to discuss the CLEAR trial: "Lenvatinib plus Pembrolizumab o...
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3.85 Med-Psych, Palliative Care, and Respect for Autonomy and Dignity with Dr. Joshua Briscoe from 2021-05-27T19:00:03
Our guest today is Dr. Joshua Briscoe of Duke University. We discuss Med-Psych (a joint internal medicine and psychiatry residency) and how it and palliative care connect to the human side to medic...
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3.84 DLBCL, Bad Cancer Drugs and Bad Twitter Users with Dr. Aaron Goodman from 2021-05-26T19:00
We're joined today by Dr. Aaron Goodman, a hematologist/oncologist at the University of California San Diego, to discuss diffuse large B-cell lymphoma (DLBCL). We talk about bad cancer drugs and ba...
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3.83 MetaResearch, Reproducibility, Expertise,&Early Career Researchers with Dr. Ioana Cristea from 2021-05-25T19:00
Today we sit down with Dr. Ioana Cristea of the University of Pavia, Italy and the Meta-Research Innovation Center at Stanford to discuss meta-research, reproducibility, and expertise. We also talk...
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3.82 Classical Hematology Chat on CVT and VITT with Drs. Sven Olson and Joseph Shatzel from 2021-05-24T19:00
Today we host a Classical Hematology Chat on thrombosis associated with COVID-19 vaccines. We're joined by Drs. Sven Olson and Joseph Shatzel of Oregon Health&Science University as we talk about ce...
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3.81 Impact of COVID-19 on Sociology, Politics, and Democracy with Genève Campbell from 2021-05-21T19:00:20
Today we are joined by Genève Campbell, scholar of democracy and government, as we discuss sociology and politics in the context of COVID-19. Back us on Patreon! www.patreon.com/plenarysessionChec...
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3.80 ESMO-Magnitude of Clinical Benefit Scale (ESMO-MCBS) with Drs. Bishal Gyawali and Nathan Cherny from 2021-05-20T19:00:10
Today we sit down with Dr. Bishal Gyawali of Queen's University in Kingston, Ontario, Canada and with Dr. Nathan Cherny of Shaare Zedek Medical Center in Jerusalem, Israel to talk about the Europea...
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3.79 Sweden's Stance on COVID-19, Hydroxychloroquine, Schools,&Mask Data with Dr. Cathrine Axfors from 2021-05-19T19:00
On today's episode, we sit down with Dr. Cathrine Axfors of the Meta-Research Innovation Center at Stanford (METRICS) to discuss how Sweden responded to COVID-19 and the nation's attention to what ...
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3.78 Astronomy, Being a Scientist, and the Culture of the Academy with Dr. Avi Loeb from 2021-05-18T19:00:16
Today we talk with Dr. Avi Loeb of the Harvard-Smithsonian Center for Astrophysics about astronomy and the culture of the academy, as well as diving into topics discussed in his new book Extraterre...
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3.77 Reporting of Race in US FDA Registration Trials with Dr. Mark Lythgoe from 2021-05-17T19:00:06
Today we talk with Dr. Mark Lythgoe, a Clinical Research Fellow at Imperial College London, on his new paper titled "Race reporting and diversity in US food and drug administration (FDA) registrati...
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3.76 COVID-19 Transmission in Schools with Dr. Christopher Whaley and Dr. Neeraj Sood from 2021-05-14T19:00:26
On today's episode, we invite Dr. Chris Whaley of RAND and Dr. Neeraj Sood of the USC Price School of Public Policy to discuss their new paper titled "Back to School: The Effect of School Visits Du...
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3.75 All Things COVID-19 with Infectious Disease Professor Dr. Paul Edward Sax from 2021-05-14T01:23:04
Today our guest is Dr. Paul Edward Sax, Clinical Director of the Infectious Disease Clinic and Professor of Medicine at Harvard Medical School. We talk about all things COVID-19. Back us on Patreo...
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3.74 Artificial Intelligence in Dermatology with Dr. Roxana Daneshjou from 2021-05-13T05:00:04
On today's episode, we interview Dr. Roxana Daneshjou, a clinical scholar in dermatology and postdoctoral research fellow at Stanford University. We talk about artificial intelligence in dermatolog...
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3.73 CheckMate 577: Adjuvant Nivolumab in Resected Esophageal or Gastroesophageal Junction Cancer from 2021-05-12T02:16:02
On today's episode, we have a short monologue for you on the recent CheckMate 577 study that was recently published in the New England Journal of Medicine. The title of the paper is "Adjuvant Nivol...
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3.72 Industry Payments to US Physicians for Cancer Therapeutics with Dr. Daniel Meyers from 2021-05-11T01:02:05
Today we're joined by Dr. Daniel Meyers of the University of Calgary who's here to discuss his new paper out now in the Journal of Cancer Policy. It's titled "Industry payments to US physicians for...
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3.71 How Research Influences Policy with Dr. Kirsten Bibbins-Domingo from 2021-05-05T17:24:46
Today we sit down with Dr. Kirsten Bibbins-Domingo, Chair of the Department of Epidemiology and Biostatistics and the inaugural Vice Dean for Population Health and Health Equity in the UCSF School ...
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3.70 The Motivation We Need to Reach the End of the COVID-19 Pandemic with Dr. Monica Gandhi from 2021-04-30T19:00:22
Today we sit down with Dr. Monica Gandhi, Associate Division Chief of the Division of HIV, Infectious Diseases, and Global Medicine at UCSF/ San Francisco General Hospital, and medical director of ...
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3.69 Reporting of Postprotocol Therapies in Multiple Myeloma with Dr. Ghulam Rehman Mohyuddin from 2021-04-29T19:00:12
Today we talk with Dr. Manni Mohyuddin of Kansas University Medical Center on his new paper out now in JAMA Network Open titled "Reporting of Postprotocol Therapies and Attrition in Multiple Myelom...
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3.68 A Career in Academic Medicine&Challenges of 2021 with Former Harvard Dean, Dr. Jeffrey Flier from 2021-04-29T04:50:25
On today's episode, we interview Dr. Jeffrey Flier, an esteemed endocrinologist and physician researcher who was Dean of the Faculty of Medicine at Harvard University for nine years (2007-2016). We...
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3.67 Thoughts on PhD Programs and Idecabtagene Vicleucel with Dr. David Russler-Germain from 2021-04-23T16:02:45
Today we bring back popular guest Dr. David Russler-Germain, a Hematology/Oncology Fellow at the Washington University School of Medicine in St. Louis, to discuss his thoughts on PhD programs (in r...
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3.66 COVID-19 Policies and Progressing Past Disagreement with Dr. Martin Kulldorff from 2021-04-16T12:00:06
Today we talk with Dr. Martin Kulldorff, a Professor of Medicine at Harvard Medical School and Brigham and Women's Hospital, about COVID-19 health policy and about disagreement. Back us on Patreon...
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3.65 Banning Books, Social Media,&Medical Education with Dr. Adam Cifu from 2021-04-14T12:00:06
Today we bring back popular guest Dr. Adam Cifu, a Professor of Medicine at the University of Chicago, to talk about the idea of banning books. the power of social media, and the current state of m...
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3.64 A Legal and Philosophical View on COVID-19 with Samantha Godwin from 2021-04-12T12:00:16
Today we are joined by Samantha Godwin, a Resident Fellow for the Information Society Project at Yale Law School, to discuss COVID-19 health policy from a legal and philosophical perspective. Back...
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3.63 The Medical Scientist Training Program with Dr. David Russler-Germain from 2021-04-08T17:06:13
Today we talk again with Dr. David Russler-Germain, a Hematology/Oncology Fellow at the Washington University School of Medicine in St. Louis, this time on the Medical Scientist Training Program (M...
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3.62 COVID-19 Transmission, Vaccines,&Olaparib with Dr. Tom Beer from 2021-04-08T01:15:18
Today we interview Dr. Tom Beer, the Deputy Director of the Oregon Health&Science University Knight Cancer Institute, about COVID-19 transmission, policy, and vaccines. We also talk about olaparib....
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3.61 The Neuroscience and Psychology of Recreational Drug Use in Adults with Dr. Carl Hart from 2021-04-06T02:32:23
Today we are joined by guest Dr. Carl Hart, a behavioral neuroscientist and Professor of Psychology at Columbia University. We discuss his research, his philosophies, and his new book "Drug Use for...
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3.60 Drugs for Acute Lymphoblastic Leukemia with Dr. Bernard Marini from 2021-03-31T00:57:48
Today we bring back popular guest Dr. Bernie Marini, a Clinical Pharmacist Specialist in Hematology at University of Michigan Medicine, to discuss treatment of Acute Lymphoblastic Leukemia (ALL). ...
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3.59 Genetic Alterations Linked to SARS-CoV-2 Acquisition and Bad Outcomes with Dr. Nathan Pearson from 2021-03-30T01:28:58
Today we are joined by genomicist Dr. Nathan Pearson, founder of Root (rootdeep.com), to discuss which genetic alterations in the host predispose to SARS-CoV-2 acquisition and bad outcomes. Gift o...
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3.58 Expertise and Disinformation with Jacob Hale Russell from 2021-03-26T22:11:46
Today we bring back popular guest Jacob Hale Russell, an Associate Professor of Law at Rutgers Law School, for a discussion on expertise, disinformation, and intellectual disagreement. Back us on...
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3.57 Career Paths and Evolution of the Oncology Randomized Clinical Trial with Dr. Christopher Booth from 2021-03-26T03:34:51
On today's episode we talk with popular guest Dr. Chris Booth of Queen's University in Kingston, Ontario, Canada about mapping out a career path after medical school and about his new paper out now...
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3.56 Quality of Control Groups in RCTs of Multiple Myeloma with Dr. Ghulam Rehman Mohyuddin from 2021-03-25T00:45:32
Today we interview Dr. Ghulam Rehman Mohyuddin of Kansas University Medical Center on his new paper out now in The Lancet Haematology titled "Quality of control groups in randomised trials of multi...
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3.55 Equity in Vaccine Distribution, Cancel Culture, and Zero COVID-19 with Dr. Matthew Smith from 2021-03-24T04:21:43
Today we sit down with Dr. Matthew Smith, an associate professor in the Northeastern University Department of Philosophy and Religion, to discuss the morality and philosophical backbone behind COVI...
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3.54 The Passing of Dr. José Baselga from 2021-03-23T02:58:46
For today's episode we have a short monologue in remembrance of famed cancer researcher Dr. José Baselga. Back us on Patreon! www.patreon.com/plenarysessionCheck out our YouTube channel: www.youtu...
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3.53 Updates on COVID-19 and Looking Back Over the Last Year with Dr. Aaron Richterman from 2021-03-19T00:53:36
Today we interview Dr. Aaron Richterman, an infectious disease specialist at Penn Medicine. We talk about updates on all things COVID-19 and we look back at how treatments, risk assessment, and beh...
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3.52 Medicine, Leadership, SARS-CoV-2, and Social Media with Dr. Bob Wachter from 2021-03-14T13:00:18
Today we interview Dr. Bob Wachter, the Chair of the Department of Medicine at University of California San Francisco. We talk about a wide range of topics including medicine, leadership, SARS-CoV-...
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3.51 COVID-19 Modeling with Youyang Gu from 2021-03-12T22:57:48
On today's episode we interview Youyang Gu, an independent data scientist who created some of the most models of the COVID-19 pandemic. He talks us through how he made the projections. His work is ...
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3.50 Evildoer Marty Makary [SHORT] from 2021-03-11T23:24:40
On today's SHORT episode, we talk about censorship, Facebook, Twitter, and the "evildoer" Dr. Marty Makary. Back us on Patreon! www.patreon.com/plenarysessionCheck out our YouTube channel: www.you...
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3.49 The Role of Government in Public Health and in COVID-19 Policy with Dr. Robert Freudenthal from 2021-03-10T01:56:35
Today we interview Dr. Robert Freudenthal, a psychiatrist in training at Barnet Enfield and Haringey Mental Health Trust in London, UK. We talk abut the power of the state and its role in public he...
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3.48 The Predictive Value of High Tumor Mutational Burden with Dr. Luc Morris from 2021-03-06T01:14:09
Today we interview Dr. Luc Morris of Memorial Sloan Kettering Cancer Center on his new paper out now in JAMA Oncology titled "Response Rates to Anti-PD-1 Immunotherapy in Microsatellite-Stable Soli...
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3.47 COVID-19 Vaccine Results, Messaging on a Patient Level,&Schools with Dr. Monica Gandhi from 2021-03-03T01:37:13
Today we interview Dr. Monica Gandhi, Associate Division Chief of the Division of HIV, Infectious Diseases, and Global Medicine at UCSF/ San Francisco General Hospital, and medical director of the ...
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3.46 COVID-19 Risk, Cases, and Transmission in K-12 Schools with Dr. Tracy Høeg from 2021-02-27T05:19:23
Today we interview Dr. Tracy Høeg on her new paper and her ongoing research into COVID-19 transmission in K-12 schools in Wisconsin, USA. Dr. Høeg is an epidemiologist and an interventional sports ...
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3.45 USMLE Steps, Residency Match,&M.D. vs D.O. with Dr. Bryan Carmody from 2021-02-24T21:31:59
On today's episode we interview Dr. Bryan Carmody, commonly known as the Sheriff of Sodium. He's a pediatric nephrologist at Children's Hospital of the King's Daughters in Virginia. We talk with hi...
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3.44 The Role of Philosophy, COVID-19 Policy, and COVID-19 Exceptionalism with Dr. Alex John London from 2021-02-17T23:54:35
Today we sit down with Dr. Alex John London, the Clara L. West Professor of Ethics and Philosophy and Director of the Center for Ethics and Policy at Carnegie Mellon University, to discuss the role...
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3.43 Reviewing the Beat AML Master Trial from 2021-02-15T19:04:39
On today’s episode we review the findings of the Beat AML study as published in Nature Medicine in an article titled “Precision medicine treatment in acute myeloid leukemia using prospective genomi...
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3.42 Overdiagnosis and Cutaneous Melanoma Diagnoses with Dr. Adewole Adamson and Dr. Benjamin Mazer from 2021-02-10T00:59:39
For today's episode, we sit down with Drs. Ade Adamson of the University of Texas at Austin Dell Medical School and Ben Mazer of Johns Hopkins Hospital to discuss their new paper out now in the New...
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3.41 Building a Meta-Research Career and Constructing COVID-19 Health Policy with Dr. John Ioannidis from 2021-02-07T18:13:58
For today's special episode, we sat down with Dr. John Ioannidis of Stanford University for an outdoor in-person interview. We take a deep dive into his work from 2000 all the way up to present day...
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3.40 COVID-19 Vaccines, Origin of SARS-CoV-2, and Pandemic Mitigation with Prof Francois Balloux from 2021-02-05T19:42:22
On today's episode we're joined by geneticist Dr. Francois Balloux, the Director of the University College London Genetics Institute and professor of computational systems biology, on pandemic miti...
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3.39 Public Health Messaging on COVID-19 with Drs. Julia Marcus and Stefan Baral from 2021-02-04T03:20:52
On today's episode we feature an in-depth interview with Dr. Julia Marcus (Associate Professor at Harvard Medical School) and Dr. Stefan Baral (Associate Professor at Johns Hopkins Bloomberg School...
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3.38 Oncology During COVID-19&RCTs from Low- vs High-Income Countries with Dr. Christopher Booth from 2021-01-29T19:18:25
On today's episode we sit down with Dr. Chris Booth of Queen's University in Kingston, Ontario, Canada to discuss his new paper out now in JAMA Oncology titled "An Analysis of Contemporary Oncology...
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3.37 Skepticism, COVID-19, and Debating Science in the Era of Trade-Offs with Jacob Hale Russell from 2021-01-27T01:12:12
On today's episode we are joined by Jacob Hale Russell, an Associate Professor of Law at Rutgers Law School. We discuss his forthcoming book on skepticism, elites, and expertise, as well as his art...
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3.36 Sustainable Ex-Vivo Seafood with Dr. Arye Elfenbein from 2021-01-22T01:42:05
On today's episode we sit down with Dr. Arye Elfenbein, a cardiologist and "doctorpreneur " to interview him on the bio-tech company he recently co-founded: Wildtype. Wildtype manufactures ex-vivo ...
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3.35 The Secrets of Vermont in Taming the COVID-19 Pandemic with Anne Sosin from 2021-01-20T04:04:21
Today we interview Anne Sosin of Dartmouth College on public health policy in Vermont and how the state has uniquely tamed the COVID-19 pandemic. Back us on Patreon! www.patreon.com/plenarysession...
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3.34 COVID-19 From a Philosopher's Point of View with Dr. Matthew Smith from 2021-01-15T02:47:26
Today we sit down with Dr. Matthew Smith, an associate professor in the Northeastern University Department of Philosophy and Religion, for a far-ranging discussion on COVID-19 from a philosopher's ...
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3.33 Hematologic Malignancies and Transplantation with Dr. Aaron Goodman from 2021-01-12T02:21:14
Today we are joined by Dr. Aaron Goodman, an Assistant Clinical Professor at the University of California San Diego, who talks with us about hematologic malignancies, transplantation, and our new p...
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3.32 Publishing Original Thought in Medical Journals with Dr. Stephen Bradley from 2021-01-08T23:56:31
Today we talk with Dr. Stephen Bradley, a General Practitioner and Clinical Research Fellow at the University of Leeds, on publishing in medical journals -- peer review, editorial practices, anti-i...
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3.31 Random Thoughts on Visiting Hospital Patients During COVID-19 and Norman Wang's Lawsuit from 2021-01-06T02:10:03
Today we have for you an episode of random thoughts. We talk over the ramifications of the strict COVID-19 policy that prevents people from visiting their dying loved ones in the hospital. We also ...
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3.30 Benefit and Risk of SpaceOAR with Dr. William Hall from 2021-01-05T04:43:41
On today's episode we interview Dr. Bill Hall, Associate Professor of Radiation Oncology and Surgery at Medical College of Wisconsin, on our new paper out now in The Lancet Oncology titled "Conside...
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3.29 Censorship in Medicine with Jonathan Darrow from 2020-12-31T02:21:03
On today's episode we discuss censorship in medicine in all its forms with legal expert Jonathan Darrow, an Assistant Professor at Harvard Medical School. Back us on Patreon! www.patreon.com/plena...
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3.28 Exploring the History of Medicine with Dr. Adam Rodman, host of Bedside Rounds from 2020-12-21T18:30:20
On today's episode we talk podcasting and the history of medicine with Dr. Adam Rodman, the creator and host of the wildly popular podcast Bedside Rounds, and a hospitalist at the Beth Israel Deaco...
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3.27 All Recent Acute Myeloid Leukemia Drugs with Dr. Bernard Marini from 2020-12-16T23:38:59
On today's episode we discuss all the new drugs for acute myeloid leukemia with Dr. Bernie Marini, a Clinical Pharmacist Specialist in Hematology at University of Michigan Medicine. Back us on Pat...
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3.26 The Importance of Debate and Dialogue with Dr. Saurabh Jha from 2020-12-15T03:59:27
Today's episode is an interview with Dr. Saurabh Jha, an Associate Professor of Radiology at the Hospital of the University of Pennsylvania, on the importance of debate and dialogue both historical...
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3.25 Public Health Policy on the Risk of COVID-19 in Children with Dr. Alasdair Munro from 2020-12-12T02:18:47
Now that we are nine months into the COVID-19 pandemic in the United States, we invite Dr. Alasdair Munro, a pediatrics infectious disease expert, back on to the show to discuss recent developments...
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3.24 KEYNOTE-177&Mathematic Models for Fighting COVID-19 with Dr. Wesley Pegden from 2020-12-04T23:04:47
This week we return to our roots of oncology and dissect the recent results from KEYNOTE-177. We also have an in-depth interview with mathematician Dr. Wes Pegden of Carnegie Mellon University on a...
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3.23 Capturing Your Audience with Dr. Zubin "ZDoggMD" Damania&JAVELIN 100 with Dr. Karine Tawagi from 2020-11-26T05:00:48
We have a short and sweet episode for you this week -- no monologue, just two deep-dives with two stellar guests. Our first interview is with Dr. Zubin Damania (known as ZDoggMD) and we cover every...
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3.22 New Podcast, Opening Schools with Dr. Vladimir Kogan, Virtual Learning with Dr. Carycruz Bueno from 2020-11-21T01:09:57
Our first guests this week are Drs. Adam Cifu and Scott Stern and are on to discuss their new podcast Symptom to Diagnosis -- based on their book of the same name -- about clinical reasoning. Next ...
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3.21 Affirmative Action with Leah Litman, Cost Implications with Dr. DeMartino,&Dr. John Mandrola from 2020-11-13T23:36:01
First up this week we interview constitutional law scholar Leah Litman, an Assistant Professor of Law at the University of Michigan, on Dr. Norman Wang and the intricacies of the laws on affirmativ...
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3.20 Public Health Messaging, COVID-19 in the U.S. Northeast, Journal Club with a Fellow from 2020-11-07T05:59:12
We have a multitude of interviews for you this week. We start by interviewing Dr. Julia Marcus of the Harvard Medical School and Harvard Pilgrim Health Care Institute on messaging around public hea...
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3.19 COVID-19 and the AIDS Pandemics with Dr. Monica Gandhi&Classical Hematology Chat from 2020-10-30T23:55:33
We talk this week with Dr. Monica Gandhi, Associate Division Chief of the Division of HIV, Infectious Diseases, and Global Medicine at UCSF/ San Francisco General Hospital, and medical director of ...
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3.18 Social Media and News with Dr. Benjamin Mazer&Caplacizumab for TTP with Dr. Tem Bendapudi from 2020-10-23T21:18:12
This week we have two fantastic interviews for you: The first is with Dr. Ben Mazer on the interplay between social media and news; the second is with Dr. Tem Bendapudi on whether Caplacizumab shou...
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3.17 COVID-19 and Schools in Norway with Dr. Atle Fretheim&Cancer Biology with Dr. Anthony Letai from 2020-10-16T23:21
This week we sit down virtually with Dr. Atle Fretheim, Research Director of the Norwegian Institute of Public Health, to talk about how Norway has responded to the COVID-19 crisis - specifically, ...
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3.16 Non-Drug Interventions with Dr. Margaret McCartney&Cancer Biology with Dr. Jason Sheltzer from 2020-10-09T22:28:25
We start this week's episode off with a monologue covering a few current events, notably the recent editorial on the COVID-19 pandemic in the USA published by the New England Journal of Medicine ti...
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3.15 COVID-19 in Children with Dr. Alasdair Munro&Pandemic Public Health with Dr. Stefan Baral from 2020-10-06T15:45:45
We start this week's episode by interviewing Dr. Alasdair Munro, a pediatrics infectious disease expert, on the risk of spread of COVID-19 in children and through schools. We end with an interview ...
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3.14 COVID-19 with Dr. John Ioannidis&Trial Eligibility with Dr. Mary-Elizabeth Percival from 2020-10-03T01:45:54
This week we have a two-hour-long, far-ranging interview with Dr. John Ioannidis of Stanford University on, broadly, meta-research and COVID-19 - including his recent controversies. We end the epis...
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3.13 COVID-19 and Schools, COVID-19 and Scott Atlas, and COVID-19 Policy from 2020-09-25T00:17:40
This week's episode is all about COVID-19. We discuss general COVID-19 health policy and how spread of SARS-CoV-2 has been managed and should be managed; we discuss whether or not schools should be...
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3.12 TMPRSS2, Cancer Imaging with Drs. Becker and Woo, Clinical Epidemiology with Dr. Thomas Newman from 2020-09-19T15:10:29
We start this week's episode by critically examining the new paper titled "Racial/Ethnic Variation in Nasal Gene Expression of Transmembrane Serine Protease 2 (TMPRSS2)" and asking, is it racist? A...
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3.11 Experts, Lockdown, Affirmative Action,&COVID-19 and Hearts with Professor Darrel Francis from 2020-09-12T03:46:18
This week's monologue touches on the credibility of expert speakers, evaluating the COVID-19 lockdown as health policy, and the anti-affirmative action white paper written by Dr. Norman Wang and it...
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3.10 Colon Cancer Screening, Vascepa Patent with Jonathan Darrow, PREVENTT with Dr. Toby Richards from 2020-09-05T16:07:03
We have a number of topics for you this week! Among them, we cover the issue of colon cancer screening, especially in the light of Chadwick Boseman's recent passing. We interview Jonathan Darrow, a...
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3.09 COVID-19 Risk, Financial Toxicity,&HALT-IT for Journal Club with Fellow Dr. Justine Ryu from 2020-08-29T00:53:59
We start this week's episode by revisiting our discussion from last week on the PNAS study on racial concordance and birthing mortality. We continue our theme of critical appraisal by then tearing ...
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3.08 Racial Concordance in Birthing Mortality&HERO for Journal Club with Fellow Dr. Michael Burns from 2020-08-22T03:01:13
This week we take a deep dive into two recently published studies, their surrounding controversy, and the broader implications. The first study was published in the journal Proceedings of the Natio...
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3.07 Lung Cancer Omics and Mortality, PPIs and COVID-19,&RECIST with Dr. Elizabeth Eisenhauer from 2020-08-15T00:53:28
We have a lot in store for you this week! We start off by evaluating two recently published studies: "Evaluation of Omics-Based Strategies for the Management of Advanced Lung Cancer" (published in ...
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3.06 COVID-19 Vaccine Access, ADAURA, QOTW,&Journal Club with Fellow Dr. Karine Tawagi from 2020-08-07T22:31:54
We start this week's episode by discussing access to investigational COVID-19 vaccines and recapping the problems with the ADAURA study. We transition from there to a Question of the Week with medi...
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3.05 LIVE! A Midsummer Night's Stream from 2020-07-30T22:41:56
This is the recording of a LIVE episode of Plenary Session in which Dr. Sue S Yom interviewed our host, Dr. Vinay Prasad, on how he built his career and how he conceptualizes his work. There's also...
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3.04 Listener Questions&MedTwitter and Risk-Benefit Profile of Ramucirumab with Dr. Bishal Gyawali from 2020-07-24T21:36:36
This week we respond to several questions sent in by listeners and then we interview Dr. Bishal Gyawali of Queen's University in Kingston, Ontario, Canada on MedTwitter, other recent events, and hi...
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3.03 The National Lung Matrix Trial&the Major Flaw of the SPRINT Trial with Dr. Mark Friedberg from 2020-07-18T01:08:58
This week we discuss two major papers: The first was just recently released in Nature and it's titled "The National Lung Matrix Trial of personalized therapy in lung cancer". The second is a few ye...
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3.02 BONUS! National Clinician Scholars Program with Dr. Hilary Seligman from 2020-07-13T23:57:55
This week's BONUS episode is a discussion of the National Clinician Scholars Program with Dr. Hilary Seligman, the head of the program at University of California, San Francisco. The deadline for t...
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3.01 Risk of COVID-19 Among Users of PPIs, Time to Treatment Initiation,&Dr. Lynora Saxinger from 2020-07-11T00:40:58
This week we discuss recent research (and the accompanying Twitter thread) on the risk of COVID-19 among users of proton pump inhibitors (PPIs). We also hold a philosophical discussion on the resea...
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2.60 BONUS! Cancer Meta-Research 101: The Lay of the Land of Cancer Research from 2020-07-07T02:01:40
This BONUS episode is the recording of a lecture given on June 18, 2020 as part of Stanford's METRICS International Forum. METRICS stands for Meta-Research Innovation Center at Stanford University....
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2.59 The Best Doctor, Selinexor,&Annotation Services for NGS with Drs. Katsoulakis and Kelley from 2020-07-03T20:46:44
This week we respond to some listener feedback from Dr. Christopher Booth and use it to talk about how to be the best hematologist-oncologist. We also discuss the SADAL study on Selinexor for patie...
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2.58 RECOVERY&Twitter, Academic Debate, and Transitioning Your Career with Dr. Andrae Vandross from 2020-06-27T02:33:40
This week we briefly cover updates on the RECOVERY trial before segueing into an interview with Dr. Andrae Vandross on Twitter (specifically #medtwitter), academic discussions, and changing your ca...
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2.57 RECOVERY, Clinical Trials in the US, EFS, Writing, Dr. Raj Chetty,&Dr. Ian Tannock from 2020-06-19T22:17:48
This week's episode is jam-packed with topics! We talk about the RECOVERY trial, the U.S. clinical trial infrastructure, event-free survival (EFS) and cost of care in acute myeloid leukemia, how lo...
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2.56 HER2CLIMB&Misinformation and Disinformation with Dr. Cailin O'Connor from 2020-06-12T16:40:19
This week we tackle the topic of tucatinib in HER2-positive breast cancer with brain metastases. We also interview Dr. Cailin O'Connor of the University of California Irvine on her research on misi...
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2.55 Hydroxychloroquine for COVID-19, ASCO, QOTW, Private Equity in Medicine with Dr. Jane Zhu from 2020-06-05T02:28:08
We start this week's episode by covering some recent research: After thoroughly critiquing the recent randomized trial of hydroxychloroquine for postexposure prophylaxis for COVID-19, we then discu...
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2.54 Classical Hematology Chat on Thrombosis in COVID-19&Drugs for COVID-19 with Dr. Walid Gellad from 2020-05-31T03:31:11
This week we talk all things COVID-19! We start with an in-depth Classical Hematology Chat with Dr. Sven Olson and Dr. Joseph Shatzel of Oregon Health&Science University on thrombosis and anticoagu...
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2.53 Why Agreeing 65% with Someone is Important&COVID-19 Health Policy with Dr. Daniel Morgan from 2020-05-23T02:11:07
This week we discuss why being open-minded enough to agree partially with someone - instead of taking an all-or-nothing approach to a discourse - is important. We also sit down with epidemiologist ...
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2.52 Malignant Audiobook, PROfound trial,&Literature and Medicine with Dr. Adam Cifu from 2020-05-16T00:42:45
This week we have an announcement -- the audiobook of "Malignant: How Bad Policy and Bad Evidence Harm People with Cancer", written and narrated by our host Vinay Prasad, is available now on Amazon...
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2.51 BONUS! Clinical Trials Part 3 from 2020-05-13T16:06:55
This BONUS lecture was a talk given to the Hematology/Oncology fellows at Oregon Health&Science University. It's part three of a three-part series on clinical trials. Back us on Patreon! www.patr...
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2.50 Neil Ferguson, Ending Lockdown,&Updates on COVID-19 Management with Dr. Benjamin Singer from 2020-05-07T22:14:36
This week's topic is all things COVID-19 -- we discuss the viral scandal of British epidemiologist Neil Ferguson's actions and how it reflects (or doesn't) on his work, we talk about the nuances of...
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2.49 COVID-19 Contrarians, Remdesivir,&Book Club on "Malignant" with OHSU HemOnc Fellows from 2020-05-02T01:44:40
This week we begin with a monologue on the recent controversy surrounding Dr. John Ioannidis's published opinions on the COVID-19 pandemic. We end with a group discussion with Oregon Health&Science...
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2.48 BONUS! Introduction to Malignant: How Bad Policy and Bad Evidence Harm People with Cancer from 2020-04-25T00:36:26
This week we have a BONUS episode for you! As a teaser to the forthcoming audiobook of "Malignant: How Bad Policy and Bad Evidence Harm People with Cancer" by Dr. Vinay Prasad (our host), Audrey Tr...
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2.47 Remdesivir, Cloth Masks,&Incentives for COVID-19 Drug Development with Dr. Ameet Sarpatwari from 2020-04-16T23:22:49
This week we start with an in-depth monologue on various new developments surrounding COVID-19, specifically the new study in NEJM on the compassionate use of remdesivir as well as the CDC's advice...
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2.46 Psychology Unearthed by COVID-19 Precautions&Polygenic Risk Score with Dr. Venk Murthy from 2020-04-11T00:47:53
This week we have a far-reaching monologue on COVID-19 and how people are reacting to the public health recommendations concerning COVID-19 (such as cancelling conferences and school, maintaining 6...
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2.45 Viral Spread of SARS-CoV-2, Rationing Resources, "Evidence Fiasco",&Classical Hematology Chat from 2020-04-01T22:57:23
This week we discuss several recent articles on the novel coronavirus (SARS-CoV-2) and COVID-19, specifically Dr. Siddhartha Mukherjee's article on the history and science of humanity's history wit...
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2.44 ICU Management of COVID-19 with Dr. Benjamin Singer from 2020-03-25T23:26:24
This week we discuss management of COVID-19 in the intensive care unit with Dr. Benjamin Singer, a pulmonary and critical care physician at Northwestern University. We discuss medications, PPE, ven...
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2.43 BONUS! Novel Coronavirus and the COVID-19 Response in Oregon with Dr. John Townes from 2020-03-18T19:32:09
This bonus episode is an interview from March 16, 2020 with Dr. John Townes, the Interim Head for the Division of Infectious Disease and the Medical Director for Infection Prevention and Control he...
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2.42 Quality-of-Life Measurement in Oncology, KnowYourTumor,&Question of the Week from 2020-03-17T00:33:15
This week we discuss two recent papers -- one we praise, one we condemn -- and then we turn to a question of the week with medical student Audrey Tran on self-improvement and "refining conviction"....
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2.41 BONUS! Clinical Trials Part 2: Crossover and Control Arms from 2020-03-11T16:13:11
This BONUS lecture was a talk given to the Hematology/Oncology fellows here at Oregon Health&Science University. It's part two of a three-part series on clinical trials. This talk is on clinical tr...
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2.40 BEACON part 2, NALA,&Molecular Pathology and Next-Generation Sequencing with Dr. David Carr from 2020-03-05T20:40:21
This week we revisit BEACON! The authors of the BEACON study have responded to the Letter to the Editor our host Dr. Vinay Prasad submitted to the New England Journal of Medicine, and we share our ...
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2.39 Effectiveness of Newer-Generation Antidepressants with Dr. Michael Hengartner from 2020-02-27T23:44:49
Our guest this week is Dr. Michael Hengartner of the Zurich University of Applied Sciences. We interview him on his work studying the long-term consequences and effectiveness of newer-generation an...
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2.38 KEYNOTE-048, Academic Currency,&Trials in Low/Mid-Income Countries with Dr. Bishal Gyawali from 2020-02-19T16:22:16
We start this episode by diving deep into KEYNOTE-048, the randomized, open-label, phase 3 study of pembrolizumab alone or with chemotherapy v.s. cetuximab with chemotherapy for recurrent or metast...
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2.37 Careerism, Presenting Abstracts, Twitter and the K-Index,&Classical Hematology Chat from 2020-02-14T23:11:17
We have a full slate for you this week! We discuss careerism in medicine, presenting abstracts at conferences, #MedTwitter, and Dr. Califf's opinions on the K-Index. We conclude the episode with ou...
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2.36 Thought Leaders, NELSON,&Reliance on P Values in Cancer Trials with Dr. Sam Rubinstein from 2020-02-07T23:09:21
This week we discuss the concept of "thought leaders" and we examine the conclusions about volume CT screening for lung cancer from the NELSON trial. We end with an interview with Dr. Sam Rubinstei...
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2.35 BONUS! How to Keep Up with the New Information in Medicine from 2020-01-31T20:07:28
This BONUS episode is the recording of a lecture given to medical students titled "How to Keep Up with the New Information in Medicine." It's a primer on the steps healthcare professionals need to ...
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2.34 Red Light, Pola for DLBCL, Hem/Onc Question of the Week,&TAILORx with Dr. Ali Khaki from 2020-01-24T21:51:52
We have a variety of topics for you this week! We tackle red light therapy, polatuzumab olatuzumab vedotin in relapsed or refractory diffuse large b-cell lymphoma; we have a hematology/oncology que...
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2.33 Olaparib and POLO&the Classical Fallacies of Cancer Screening with Dr. H Gilbert Welch from 2020-01-15T23:10:20
This week we're treating you to a recording of the Grand Rounds lecture on overdiagnosis and cancer screening that Dr. H Gilbert Welch gave at Oregon Health&Science University on October 30, 2019. ...
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2.32 BONUS! Clinical Trials Part 1: Thinking Better About Cancer Medicine from 2020-01-10T23:00:13
This BONUS lecture was a talk given to the Hematology/Oncology fellows here at Oregon Health&Science University. It's part one of a three-part series on clinical trials, titled "Thinking Better Abo...
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2.31 Listener Questions, Responsibility of Reviewers,&Duration of Response with Dr. Bishal Gyawali from 2020-01-07T23:51:54
This week we answer a few questions: the first is from Patreon backer, Harry Hong, on Kaplan-Meier curves. The second is from a student at Mount Sinai Medical School who reached out with some ethic...
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2.30 Questions from a Medical Student&Epidemiology with Dr. Ellie Murray from 2020-01-03T23:18:57
This week we return to our discussion of going after soft targets vs hard targets, but this time with a focus on how it applies to building a burgeoning career in medicine, in our segment Questions...
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2.29 Time from Diagnosis to Treatment in AML and Real-World Data with Dr. Sherrie Aspinall from 2019-12-27T17:56:31
This week we wonder incredulously how this abstract from ASH titled "Time from diagnosis to treatment does not affect outcome in intensively treated patients with newly diagnosed acute myeloid leuk...
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2.28 Trastuzumab in Later Lines of Therapy for HER2+ Breast Cancer, Kaplan-Meier Curves,&Patreon from 2019-12-20T18:54:02
We're back in Plenary Session HQ! We have multiple topics for you this week. We cover the use of trastuzumab in later lines of therapy for HER2+ metastatic breast cancer, we take a listener questio...
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2.27 BONUS! Use of Bone-Modifying Agents Among Medicare Beneficiaries with MM with Dr. Arjun Gupta from 2019-12-12T17:31:02
This BONUS episode is an interview with Dr. Arjun Gupta, a second-year hem/onc fellow at Johns Hopkins University, on his new paper out TODAY in JAMA Oncology titled ''Use of Bone-modifying Agents ...
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2.26 Questions of the Week: Hematology/Oncology, USMLE Step 2 CK,&a bonus Hematology/Oncology from 2019-12-09T19:39:13
This is the last week of pre-recorded episodes -- we'll be back next week with a fresh, hard-hitting monologue. In the meantime, we have three questions of the week for you. Two are inspired by the...
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2.25 Questions of the Week: Hematology/Oncology, the USMLE Step 2 CK,&One From a Med Student from 2019-12-02T19:02:06
Our host is still out of town, but don't worry -- we have some questions of the week to tide you over. The first is inspired by the hematology/oncology boards, presented by Dr. Sven Olson; the seco...
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2.24 Questions of the Week: the USMLE Step 2 CK, Hematology/Oncology,&One From a Med Student from 2019-11-26T14:59:08
This week our host is still in Australia, but we have some questions of the week saved for you! The first is inspired by the USMLE Step 2 CK, presented by Ian Straehley; the second is inspired by t...
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2.23 Question of the Week&Ethics and Inefficiencies of Clinical Trials with Dr. Jonathan Kimmelman from 2019-11-20T18:21:59
First up this week is Question of the Week inspired by the Hematology/Oncology boards, with Dr. Sven Olson. No monologue on current trials this week because our host is still in Australia, so we co...
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2.22 Question of the Week&EMR, Talking to Patients, and Being a Doctor with Dr. Robert Hirschtick from 2019-11-15T00:13:06
This week we have a question of the week from Ian Straehley, inspired by the USMLE Step 2 CK, as well as an interview with Dr. Robert Hirschtick of Northwestern University on what it means to be a ...
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2.21 Aiming for the Hard Targets&Harm From Screening and Overdiagnosis with Dr. H Gilbert Welch from 2019-11-08T18:30:16
We begin this week's episode by addressing a listener's feedback to our discussion of smoldering multiple myeloma. We then expand on our critique of 'going after the soft targets' (criticizing stud...
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2.20 "Courageous Skeptics", Lenalidomide, QOTW, and a Political Conversation with Dr. Andy Saultz from 2019-11-01T23:55:27
We begin this week's episode with a thoughtful discussion of the internet's "courageous skeptics". Then, after lamenting the way in which the recent study "Randomized Trial of Lenalidomide Versus O...
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2.19 Remembering Dr. Bernard Fisher&Self-Diagnosis with Dr. Mark Lewis from 2019-10-25T19:20:31
This week we give a short monologue on the late Dr. Bernard Fisher's legacy in the field of oncology, and then dive into a far-ranging interview with Dr. Mark Lewis of Intermountain Healthcare on h...
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2.18 Questions of the Week, Talking About Toxicity, ASCO Guidelines Authors' COI with Dr. Eitan Amir from 2019-10-18T22:49:36
This week we begin with a critique of the recent perspective article in the New England Journal of Medicine, titled "Talking about Toxicity — 'What We’ve Got Here Is a Failure to Communicate'". Aft...
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2.17 Questions of the Week, BEACON,&Use of Subacuate Rehab with Dr. Jonathan Yeh from 2019-10-08T19:23:37
We start this week's episode with a quick breakdown of why the recent BEACON trial is "the worst trial" host VP has ever read. After that, we have two questions of the week: one from medical studen...
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2.16 FLAURA&What Truly Matters in the Career of an Academic Physician with Dr. Vinay Prasad from 2019-10-02T22:27:49
This week we break down the limitations of the recent FLAURA trial and then we're back in the Plenary Session Mobile Command Unit! We have a special guest host, Dr. Christopher Booth of Queen's Uni...
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2.15 Bonus! The Value of Progression-Free Survival as a Treatment Endpoint with Dr. Michael Raphael from 2019-09-26T15:04:05
This BONUS episode is an interview with Dr. Michael Raphael of Sunnybrook Health Sciences Centre in Toronto, Ontario on his new paper out today in JAMA Oncology: "The value of progression-free surv...
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2.14 Questions of the Week&Qualifications of a Fellowship Applicant with Dr. Jeremy Cetnar from 2019-09-24T22:24:47
This week we sit down with Dr. Jeremy Cetnar, director of the Oregon Health&Science University Hematology&Oncology Fellowship Program. In this far-ranging interview, we discuss what he is looking f...
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2.13 BONUS! RCTs Supporting Approvals of Cancer Drugs by EMA with Dr. Huseyin Naci from 2019-09-20T22:50:18
On this week's BONUS episode, we sit down with Dr. Huseyin Naci, Assistant Professor of Health Policy at the London School of Economics, to discuss his new paper that came out Wednesday (producer's...
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2.12 Questions of the Week, Ethics of RCTs,&Transmission and Medical Overuse with Dr. Dan Morgan from 2019-09-17T18:01:40
We begin this week's episode by revisiting last week's topic on the ethics of randomized controlled trials (RCTs) to address some of the controversy stirred up by our episode. We transition from th...
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2.11 Questions of the Week, When RCTs are Necessary,&AYA Oncology with Dr. Adam Duvall from 2019-09-12T16:44:22
After a hiatus from our segment on reviewing recent trials, we return to discuss the need for randomized controlled trials (RCTs). In the wake of the 2019 World Conference on Lung Cancer, we focus ...
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2.10 Questions of the Week: the USMLE Step 2 CK, the MKSAP,&Hematology/Oncology from 2019-09-05T19:33:23
We have three questions for you this week: one from Ian Straehley, inspired by the USMLE Step 2 CK; one from Dr. Derrick Tao, inspired by the MKSAP; and one from Dr. Sven Olson on hematology and on...
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2.09 Questions of the Week&Informed Consent in Clinical Trials with Dr. Lynn Jansen from 2019-08-28T17:13:37
We start this week with two Questions of the Week: the first is from Ian Straehley on the USMLE Step 2 CK, and the second is from Dr. Sven Olson on hematology/oncology. We end with an interview wit...
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2.08 Questions of the Week: the MKSAP, the USMLE Step 2 CK,&From a Med Student from 2019-08-22T21:42:08
We have three questions for you this week: one from Dr. Derrick Tao, inspired by the MKSAP; one from Ian Straehley, inspired by the USMLE Step 2 CK; and one from Audrey Tran, inspired by her journe...
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2.07 Translational Research&Physical Examination Pet Peeves with Dr. Adam Cifu from 2019-08-16T17:16:58
We start this week's episode with a Question of the Week from medical student Audrey Tran on translational research and medical student training. Afterwards, we have an in-depth interview with Dr. ...
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2.06 Heart Failure, Choosing a Specialty,&the Bayesian Approach with Dr. Frank Harrell from 2019-08-06T23:31:55
We're back with more questions of the week! Our first question, from Ian Straehley, is inspired by the USMLE Step 2 CK; our second question, from Audrey Tran, is on deciding on a medical specialty....
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2.05 Reup! Cancer Screening 101 with Dr. Adam Obley from 2019-07-31T15:26:18
In this REUP episode, we replay a section of our interview with Dr. Adam Obley of OHSU: a primer on cancer screening. This audio was first aired on episode 2.03. Not So Silver Lining: doi.org/10.1...
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2.04 Reup! Tumor-Treating Fields for Glioblastoma with Dr. Michael Hayes from 2019-07-30T19:33
In this REUP episode, we replay a section of our interview with Dr. Michael Hayes of Kaiser Permanente. This audio was first aired on episode 2.01. The interview is on the relationship between conf...
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2.03 Dr. Charles Moertel and the Modern Oncologist&Cancer Screening 101 with Dr. Adam Obley from 2019-07-23T22:37:45
This week we launch a new segment on Plenary Session: Question of the Week! We invite Dr. Sven Olson on to ask a sample hematology/oncology boards question and we invite Audrey Tran on to ask a que...
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2.02 BONUS! Improving Access to Prescription Drugs through Policy Change with Dr. Stacie Dusetzina from 2019-07-17T19:13:46
This BONUS episode is a recording of a lecture that Dr. Stacie Dusetzina of Vanderbilt University gave for grand rounds at OHSU on June 19, 2019. The lecture is on the cost of prescription drugs an...
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2.01 Selinexor, ECHELON-2, Parachutes, Tumor-Treating Fields,&MedTwitter from 2019-07-12T21:50:27
Welcome to season 2! We're starting this season off with a little bit of everything: a critique of the FDA's accelerated approval of selinexor for penta-refractory multiple myeloma; an interview wi...
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1.68 Voxeletor with Dr. Olson&Humanizing Cancer, Defining Cancer, and more with Dr. David Steensma from 2019-07-05T18:01:16
We begin this week's episode by breaking down the recent phase III trial on voxeletor in sickle cell disease with Dr. Sven Olson of OHSU. Next, we feature guest Dr. David Steensma of the Dana-Farbe...
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1.67 MONALEESA-7 and the Cost of Cancer Drugs with Dr. Stacie Dusetzina from 2019-06-27T22:53:42
This week we begin the episode by discussing MONALEESA-7 and why ribociclib has been shown to increase overall survival while palbociclib has not. We finish the episode with an in-depth interview w...
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1.66 Employing Medical Writers&Frequentist vs Bayesian Methods with Dr. Allen Pannell from 2019-06-20T19:19:46
This week we open with a critical take on our current system of disseminating scientific research, specifically focusing on the prevalence of -- and dependence on -- medical writers. In the second ...
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1.65 BONUS! Focusing and Building Your Presence on Twitter from 2019-06-12T23:24:49
In this BONUS episode we give advice on how to use Twitter effectively: how to focus your content, how to build your Twitter following, and how to conceptualize of the platform as an information ne...
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1.64 Effectiveness of Cancer Screening with Dr. Joaquín Chapa and POLO with Dr. Emerson Chen from 2019-06-06T18:31:06
This week we discuss the recent paper "Interpreting the Effectiveness of Cancer Screening From National Population Statistics: Is It Sound Practice?" with its author, Dr. Joaquín Chapa of OHSU. We ...
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1.63 POLO, TITAN,&from ASCO: FDA Approval, Surrogate Endpoints, and Patient Experience from 2019-06-04T17:27:54
This week we cover some of the highlights from this year's ASCO annual meeting. We discuss the POLO study "Maintenance Olaparib for Germline BRCA-Mutated Metastatic Pancreatic Cancer" and the TITAN...
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1.62 Rates of Cancer Screening, BILCAP Outcry, Waterfall Plots and Response Rate,&Dr. Jeff Sharman from 2019-05-23T20:47:49
We begin this episode by responding to listener feedback from episode 1.61's discussion of clinic appointment time and rates of cancer screening. We also tackle listeners' outcry over our take-down...
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1.61 Postpublication Metrics of RCTs, PCP Appointment Time, Bortezomib,&Dr. Christopher Booth from 2019-05-15T23:13:06
This week we cover three papers -- "Postpublication Metrics of Randomized Clinical Trials With and Without Null Findings" by Murray et al. in JAMA, "Association of Primary Care Clinic Appointment T...
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1.60 I-PREDICT, Flawed Phase I Trials,&the Cost of Drugs with Dr. Daniel Hartung from 2019-05-09T23:05:32
We revisit I-PREDICT, discuss the "Imputability of Adverse Events to Anticancer Drugs" (a letter published recently in the New England Journal of Medicine), and interview Dr. Daniel Hartung of Oreg...
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1.59 BONUS! Should Evidence Come with an Expiration Date? with Palmer Greene from 2019-05-08T22:07:37
In this BONUS episode, we interview Palmer Greene, a fourth-year medical student at the University of Chicago Pritzker School of Medicine, on his recent paper: "Should Evidence Come with an Expirat...
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1.58 Magic Mouthwash with Dr. Arjun Gupta&Precision Oncology with Dr. Talal Hilal from 2019-05-07T16:12:12
This week we discuss three paired papers on precision oncology published in Nature Medicine and then, later in the episode, go in-depth on the implications of these negative studies with Dr. Talal ...
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1.57 BONUS! Control Arm Quality in RCTs Leading to Anticancer Drug FDA Approval with Dr. Talal Hilal from 2019-05-02T16:58:55
In this BONUS episode, we interview Dr. Talal Hilal of the Mayo Clinic on his paper that was published today in JAMA Oncology, titled "Analysis of Control Arm Quality in Randomized Clinical Trials ...
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1.56 BONUS! Real World Data&the Search for Meaningful Cancer Care with Dr. Christopher Booth from 2019-05-01T23:01:25
This BONUS episode is the recording of a Grand Rounds lecture that Dr. Christopher Booth of Queen's University in Kingston, Canada gave this morning (May 1, 2019) at OHSU. The title is "Achieving t...
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1.55 Role of a Professional Society&More with Dr. Cliff Hudis of ASCO from 2019-04-29T22:20:46
This week we sit down with Dr. Cliff Hudis, the CEO of the American Society of Clinical Oncology, to discuss the role of a professional society, the evolution of oncology, building a career, and mo...
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1.54 Association of Patient Characteristics and Tumor Genomics with Clinical Outcomes&SABR-COMET from 2019-04-18T17:00:50
In this week's episode, we break down two recently published papers. The first is "Association of Patient Characteristics and Tumor Genomics With Clinical Outcomes Among Patients With Non–Small Cel...
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1.53 CALGB 50303, REMoDL-B,&REMS, Orphan Drug Act, and Role of the FDA with Dr. Ameet Sarpatwari from 2019-04-11T17:05:15
We begin this episode with a discussion of two recent clinical trials in lymphoma: CALGB 50303 and REMoDL-B, respectively published in the Journal of Clinical Oncology and The Lancet Oncology. We i...
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1.52 BILCAP&DOACs for Thromboprophylaxis in Patients with Cancer with Dr. Sven Olson from 2019-04-04T16:25:09
In this week's episode we critique the statistics of the recent trial "Capecitabine compared with observation in resected biliary tract cancer (BILCAP): a randomised, controlled, multicentre, phase...
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1.51 BONUS! Study Time Reduction Using Surrogate End Points with Dr. Emerson Chen from 2019-04-02T19:27:20
In this BONUS episode, we sit down for a quick interview with Dr. Emerson Chen of OHSU on his recent paper in JAMA Internal Medicine on how using surrogate end points as opposed to overall survival...
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1.50 Replacing RCTs, Physicians on Twitter, Open-Access,&Orthopedics with Dr. Kathryn Schabel from 2019-03-29T19:04:35
This week we tackle the recent paper published in the Journal of Clinical Oncology titled "Comparison of Population-Based Observational Studies With Randomized Trials in Oncology" as well as a coup...
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1.49 Student Questions, Boeing 737 Max, Pancreatic Surveillance, Leukemia Drugs with Dr. Elihu Estey from 2019-03-22T18:25:37
We begin this episode by answering questions from a med student who is a Plenary Session fan. We transition from there to a discussion of the recent news stories on the FAA's handling of the Boeing...
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1.48 Falsified Data in Meta-Analyses and the Expert Halo Effect with Dr. Stephanie Halvorson from 2019-03-13T23:04:07
This week we dive deep into an article in JAMA IM on falsified data in meta-analyses. We also discuss the recent JAMA viewpoint "Reducing the Expert Halo Effect on Pharmacy and Therapeutics Committ...
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1.47 BONUS! Medical Reversal: Class Lecture from 2019-03-11T23:06:57
This BONUS episode is a lecture on medical reversal that was pre-recorded for a class at Harvard Medical School. The recording was played for students in February of 2019 and followed by a Q&A. The...
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1.46 BONUS! Personal Finances with Dr. Tom Beer from 2019-03-08T17:10:06
In this bonus episode, we bring back Dr. Tom Beer of OHSU from episode 1.33 to discuss how to manage your personal finances. The interview is aimed at young physicians, but there is something for a...
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1.45 Real-World Data, Gottlieb,&Using the EHR for Meaningful Improvement with Dr. Deborah Cohen from 2019-03-06T22:10:32
This week's episode begins with praise for the recent article by Booth CM, Karim S, and Mackillop WJ on real-world data published in Nature Reviews Clinical Oncology. Next, we tackle the resignatio...
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1.44 BONUS! Screen Time and Children's Performance from 2019-03-01T23:25:53
This BONUS episode is the recording of a lecture given as part of the medical school class Appraising Medical Literature, taught at OHSU. This clip from the class critiques the recent JAMA Pediatri...
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1.43 Andexanet Alfa with Dr. Tom Deloughery&National Medicaid Policy with Dr. John McConnell from 2019-02-22T23:17:58
In this episode we discuss the controversy over the recent article in NEJM, "Full Study Report of Andexanet Alfa for Bleeding Associated with Factor Xa Inhibitors", with Dr. Tom Deloughery of OHSU....
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1.42 Caplacizumab for TTP with Dr. Sven Olson&Economics of Drug Pricing with Dr. Inma Hernández from 2019-02-13T18:47:02
In the first half of this episode, Dr. Sven Olson of OHSU joins us to help critique the recent NEJM paper, "Caplacizumab Treatment for Acquired Thrombotic Thrombocytopenic Purpura". In the second h...
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1.41 Geneva Oath and Financial Relationships Among Guideline Authors with Dr. Joshua Niforatos from 2019-02-09T00:35:06
We feature two interviews this week: the first is a hallway conversation with [soon-to-be] Dr. Antonious Hazim of OHSU on the Declaration of Geneva and the second is a discussion with [soon-to-be]D...
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1.40 The World of Hematology with Dr. Thomas Deloughery from 2019-02-06T00:46:38
This episode features an interview with hematologist Dr. Thomas Deloughery of OHSU. We cover a broad range of topics including 23andMe, wilderness medicine, academia, and Twitter. We'll be back nex...
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1.39 Looking Back On a Tenure in Medicine with Dr. Alex Denes from 2019-02-02T00:34:26
In this episode we interview Dr. Alex Denes of OHSU on his decades-long career in medicine: what practices have changed and what have stayed the same. No monologue this week - we'll be back next we...
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1.38 Lartruvo, New Directions for Cancer Trials, Gene Expression Profiling,&Dr. Miriam Knoll from 2019-01-26T00:47:17
In this episode we tackle Eli Lilly's drug Lartruvo (olaratumab) and the under-powered phase II trial that led to its FDA accelerated approval; a viewpoint in JAMA on new directions for cancer tria...
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1.37 BONUS! Medical Reversal for a General Audience from 2019-01-18T16:34:06
This BONUS episode is the recording of a talk given at the Salem City Club on January 11, 2019. It's the talk on medical reversal that has been featured in previous episodes, but this time the form...
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1.36 Generic Price Competition&Military Surgical Advances with Dr. Martin Schreiber from 2019-01-15T20:06:15
This week we dive into the recent paper by Drs. Cole and Dusetzina titled "Generic Price Competition For Specialty Drugs: Too Little, Too Late?". We also have an interview with Dr. Martin Schreiber...
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1.35 BONUS! Conflict of Interest in Oncology from 2019-01-10T23:03:09
This BONUS episode is the recording of a lecture given to the Bioethics Study Group at OHSU on January 9, 2019 on conflict of interest, specifically in the field of oncology. Backers of our Patreon...
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1.34 Endpoints in ECOG-ACRIN 2511, Update to KEYNOTE-024,&Mentorship with Dr. Joseph Shatzel from 2019-01-10T16:53:24
In this episode, we discuss two recent papers published in the Journal of Clinical Oncology: ECOG-ACRIN 2511 and the update adding overall-survival and crossover results to KEYNOTE-024. We end with...
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1.33 Guarantee-Time Bias&Trials, Philanthropy, and Cancer Research with Dr. Tom Beer from 2019-01-05T00:07:08
In this episode we discuss guarantee-time bias in the context of the recent JAMA Oncology paper titled "Profiling Preexisting Antibodies in Patients Treated With Anti–PD-1 Therapy for Advanced Non–...
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1.32.1 Radiation Oncology with Dr. Brian Kavanagh from 2019-01-04T20:51:15
Episode 1.32 ran a little long, so this is episode 1.32.1 - we broke out the interview with Dr. Brian Kavanagh, the Chairman of Radiation Oncology at the University of Colorado, to make the intervi...
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1.32 Rating Metrics, Conflict of Interest in the News,&Radiation Oncology with Dr. Brian Kavanagh from 2019-01-03T00:19:16
This week we discuss various academic indices including the h-index and the new Altmetric score, and we go over the recent NY Times article on conflict of interest. We end with an interview with Dr...
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1.31 Ketogenic Diet, COMET-1 and COMET-2, the Health Insurance Marketplace with Dr. Jane Zhu from 2018-12-27T00:45:11
We begin this episode with a discussion of Dr. Mukherjee's ongoing study combining a ketogenic diet with PI3 kinase inhibition. We continue with a take on a recent reanalysis of COMET-1 and COMET-2...
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1.30 BONUS! Clinical Trial Endpoints, Drug Approval, Incentives in Oncology from 2018-12-19T17:02:05
This BONUS episode is the recording of a lecture given to the National Breast Cancer Coalition on December 11, 2018. It's on clinical trial endpoints, FDA drug approval, and incentives in oncology....
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1.29 RCT of Parachutes and Frameworks for Internal Medicine with Dr. Andre Mansoor from 2018-12-18T00:51:24
We begin this episode with a critique of the recent paper in the BMJ, "Parachute use to prevent death and major trauma when jumping from aircraft: randomized controlled trial" and we end it with an...
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1.28 Questionable FDA Drug Approvals and Building a Career with Dr. Chadi Nabhan from 2018-12-13T00:32:17
In this episode we critique two recent FDA drug approvals (venetoclax in combination with azacitidine or decitabine or low-dose cytarabine; glasdegib in combination with low-dose cytarabine -- both...
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1.27 BONUS! Medical Reversal from 2018-12-06T22:56:29
This BONUS episode is the recording of a lecture given to hospitalists at Kaiser Permanente on November 14, 2018. It's a slightly different version of the talk on medical reversals that we recorded...
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1.26 Lesson From an ASH Abstract, Behind the Scenes of a Residency Program with Dr. Sima Desai from 2018-12-04T22:27:45
Having just returned from the 2018 American Society of Hematology (ASH) Annual Meeting, we begin this episode by discussing the abstract of a study that stretches its conclusions. We dedicate most ...
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1.25 Welch's Legacy, Interpreting NGS, Uncertainty over Pregabalin, Beyond EBM with Dr. Sam Edwards from 2018-11-27T22:15:18
In this episode we discuss: Dr. Gilbert Welch's Wikipedia page and how we should keep his decades of work in perspective, a Twitter conversation between experts on differing interpretations of resu...
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1.24 Useless Medical Conferences and Dr. Adam Obley on Vascepa, Fish Oil, Vitamin D and Methotrexate from 2018-11-20T00:28:15
In this episode we discuss John Ioannidis' article on the uselessness of medical conferences, published in JAMA: "Are Medical Conferences Useful? And for Whom?", followed by an interview with retur...
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1.23 BONUS! Developing Technology with Fewer Reversals: Maybe We Need More Translation Failure from 2018-11-15T22:14:28
This BONUS episode is the recording of a lecture given as part of the Biomedical Engineering Seminar series at Oregon Health&Science University on November 9, 2018. The talk is on how to move techn...
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1.22 Elo-Pom-Dex, Immunotherapy Combos, Inherent Bias, and the FDA with Dr. Erick Turner from 2018-11-13T01:12:43
In this episode, we tackle the recent papers in the New England Journal of Medicine on "Elotuzumab plus Pomalidomide and Dexamethasone for Multiple Myeloma" and "Immunotherapy Combinations in Multi...
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1.21 Nab-Paclitaxel in CCA, OS of PALOMA-3, Transparency, and Dr. Talal Hilal's Advice for Trainees from 2018-11-06T17:03:29
In this episode we question the conclusions of the phase II trial "Nab-Paclitaxel and Gemcitabine as First-line Treatment of Advanced or Metastatic Cholangiocarcinoma", review the long-term overall...
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1.20 Precision Oncology: Some Benefit, Mostly Hype and Mentorship with Dr. Andrae Vandross from 2018-10-30T21:06:50
We begin this episode analyzing the unrepentant hype of precision oncology in a monologue that was originally one half of a debate titled: "Is Precision Oncology Generating Patient Benefit or Just ...
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1.19 BONUS! Introduction to Cancer Drug Policy from 2018-10-26T17:41:50
This BONUS episode is the recording of a lecture given as part of a Cancer Intersession course for med students at Oregon Health&Science University on October 25, 2018. The talk is an introduction ...
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1.18 IMpassion130 and Hot-Spotting with Dr. Brian Chan from 2018-10-23T21:17:24
In this episode we evaluate the IMpassion130 trial on the use of atezolizumab in triple-negative breast cancer. We also interview Dr. Brian Chan of OHSU on a randomized controlled trial he's runnin...
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1.17 BONUS! Interpretation of Cancer Clinical Trials from 2018-10-22T22:03:50
This BONUS episode is the recording of a two-part talk addressed to oncology fellows given at Oregon Health&Science University on October 5 and October 12, 2018. The talk is on how to interpret can...
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1.16 BONUS! Crowdsourcing Data Analysis and Medical Reversal: Why 40% of What We Do is Wrong from 2018-10-17T22:13:38
This BONUS episode is the recording of the Hospitalist Grand Rounds given at Oregon Health&Science University on October 11, 2018. The talk is on medical reversal. Before the talk we discuss the pa...
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1.15 Minimally Effective Treatments, CheckMate 331, and Dr. Adam Obley on Low-Value Healthcare from 2018-10-16T20:23:37
In this episode we review the recent paper in Nature Reviews Clinical Oncology by Booth, C.M. and Detsky, A.S. titled "Why patients receive treatments that are minimally effective?". We discuss the...
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1.14 BONUS! Immunotherapy in Desperation and the Pennington Lecture: Myths of Medicine and Marketing from 2018-10-12T19:19:52
This BONUS episode is the recording of the 22nd annual Pennington Lecture given at Oregon Health&Science University on September 21, 2018. The lecture is on seven myths of medicine and marketing. B...
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1.13 KEYNOTE-189, Dr. Talal Hilal on MRD, and Medical Education with Dr. Adam Cifu from 2018-10-08T23:50:42
Listen in for a breakdown of the good and the bad of KEYNOTE-189(trial published in NEJM), a discussion with Dr. Talal Hilal of the Mayo Clinic on the rise of minimal residual disease as a clinical...
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1.12 BONUS! Evidence-Based Medicine Has Been Hijacked in Oncology from 2018-10-03T23:57:08
This BONUS episode is the recording of a Grand Rounds talk given at Oregon Health&Science University on September 19, 2018. The talk was inspired by the article by JPA Ioannidis titled "Evidence-ba...
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1.11 Peanut Gallery, Research Parasites, Appendectomies, HRQoL and PFS, Dr. Bishal Gyawali from 2018-10-02T22:55:34
We discuss Dr. Califf's comment on the "social media peanut gallery of experts", Dr. Drazen's comment on "research parasites" and his retirement from NEJM, the recent paper in JAMA on long-term fol...
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1.10 Criticism via Twitter, PACIFIC, PCI for CAD, and Dr. Rebecca Cooney of The Lancet from 2018-09-25T23:30:47
Today we tackle some cardiologists' opposition to criticizing clinical trials on Twitter, the PACIFIC trial on durvalumab in stage III non–small-cell lung cancer, and the recent paper in Heart: "Pe...
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1.09 Response Rate in Phase I trials, JACOB, and MI, Stroke, and Metastasis as Hard Endpoints from 2018-09-20T19:47:47
Special episode! We discuss the recent correspondence in NEJM on response rate in phase I clinical trials, the JACOB trial published in The Lancet Oncology on pertuzumab for HER2-positive gastric c...
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1.08 Hyperprolific authors, NCCN with Jeff Wagner, and Dr. Renee Dversdal on Ultrasounds from 2018-09-14T23:53:37
In this episode we discuss hyperprolific authors and the recent comment in Nature by JPA Ioannidis, R Klavans,&KW Boyack; NCCN guidelines with fourth-year medical student Jeffrey Wagner; and point-...
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1.07 Adjuvant Sunitinib in RCC, future of EBM with Dr. John Mandrola from 2018-09-11T20:38:27
In this episode we discuss the USA FDA's recent approval of sunitinib as the adjuvant treatment for patients with resected renal cell carcinoma who are at high risk of relapse. We also interview ca...
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1.06 RELEVANCE, Jenny Gill, and Dr. Catherine Livingston of the Oregon Health Authority from 2018-09-07T20:12:20
In this episode we break down the RELEVANCE trial published in the New England Journal of Medicine; discuss big data in observational studies with Jenny Gill, MS; and interview Dr. Catherine Living...
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1.05 Cost and Efficacy of Cancer Drugs, ECHELON-1, Dr. Derrick Tao, and EBM with Dr. Martha Gerrity from 2018-09-05T21:43:47
In this episode we cover the cost and efficacy of cancer drugs; review ECHELON-1; interview Dr. Derrick Tao of OHSU about his recent Lancet Oncology paper on poor control arms; and discuss evidence...
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1.04: Nutritional Epi, Lenvatinib, Nivo and Ipi for Melanoma, and Dr. Avi O'Glasser from 2018-08-30T17:12:54
This week's episode is on nutritional epidemiology by JPA Ioannidis; lenvatinib for hepatocellular carcinoma; nivolumab and ipilimumab for melanoma; and #medtwitter with Dr. Avi O Glasser from OHSU.
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1.03: RWE, Right to Try, Talazoparib, Nivolumab, and Dr. Andrae Vandross from 2018-08-21T23:07:59
We're moving to our new format. We begin with a monologue of the most noteworthy articles in this week's news. We'll be talking about real-world evidence, Right to Try, talazoparib, and the FDA app...
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1.02: HemOnc Fellowship and Hype in Cancer Medicine with Dr. Jeremy Cetnar from 2018-08-16T23:48
In episode 2, we discuss the fellowship program and then take a deep dive into hype surrounding cancer drugs. Our guest is Jeremy Cetnar, MD from Oregon Health&Science University.
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1.01: Introduction and Dr. Adam Obley from 2018-08-14T23:22:58
Join us for an introduction to who we are and what our podcast is about, then stick around for a hard-hitting discussion of evidence-based medicine, randomized controlled trials, sham controls, and...
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