Prostate Cancer | Philip Kantoff, MD - a podcast by Dr Neil Love
from 2021-02-01T22:00
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Prostate Cancer Update, Issue 1, 2021 — Part 2: Our interview with Dr Kantoff highlights the following topics as well as cases from his practice:
- Optimal management of metastatic CRPC (mCRPC);? promising agents and strategies under investigation — Presentation (0:00)
- Management of de novo metastatic prostate cancer; recommendations for screening and implications for clinical presentation (26:00)
- Benefit with the addition of chemotherapy or secondary hormonal therapy to ADT for patients with metastatic prostate cancer (31:22)
- Choice of androgen receptor inhibitor for patients with metastatic prostate cancer; impact of COVID-19 on therapeutic decision-making (37:00)
- Molecular profiling for patients with prostate cancer; spectrum of related genetic alterations (43:49)
- Activity of the AKT inhibitor ipatasertib in patients with mCRPC (49:22)
- Role of immune checkpoint inhibitors alone and in combination with targeted therapy for mCRPC (51:20)
- Efficacy and tolerability of radium-223 in patients with CRPC and bone metastases (56:36)
- Activity of PARP inhibitors in patients with mCRPC (1:02:00)
- CARD trial results: Improvement in overall survival with cabazitaxel versus enzalutamide or abiraterone for patients with mCRPC previously treated with docetaxel who experienced rapid disease progression on a prior androgen receptor-targeted agent (1:07:07)
CME information and select publications
Further episodes of Research To Practice | Oncology Videos
Further podcasts by Dr Neil Love
Website of Dr Neil Love