Prostate Cancer | Philip Kantoff, MD - a podcast by Dr Neil Love

from 2021-02-01T22:00

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Prostate Cancer Update, Issue 1, 2021 — Part 2: Our interview with Dr Kantoff highlights the following topics as well as cases from his practice:

  • Optimal management of metastatic CRPC (mCRPC);? promising agents and strategies under investigation — Presentation (0:00)
  • Management of de novo metastatic prostate cancer; recommendations for screening and implications for clinical presentation (26:00)
  • Benefit with the addition of chemotherapy or secondary hormonal therapy to ADT for patients with metastatic prostate cancer (31:22)
  • Choice of androgen receptor inhibitor for patients with metastatic prostate cancer; impact of COVID-19 on therapeutic decision-making (37:00)
  • Molecular profiling for patients with prostate cancer; spectrum of related genetic alterations (43:49)
  • Activity of the AKT inhibitor ipatasertib in patients with mCRPC (49:22)
  • Role of immune checkpoint inhibitors alone and in combination with targeted therapy for mCRPC (51:20)
  • Efficacy and tolerability of radium-223 in patients with CRPC and bone metastases (56:36)
  • Activity of PARP inhibitors in patients with mCRPC (1:02:00)
  • CARD trial results: Improvement in overall survival with cabazitaxel versus enzalutamide or abiraterone for patients with mCRPC previously treated with docetaxel who experienced rapid disease progression on a prior androgen receptor-targeted agent (1:07:07)

CME information and select publications

Further episodes of Research To Practice | Oncology Videos

Further podcasts by Dr Neil Love

Website of Dr Neil Love