JALA February 2013 Podcast: Reversible Regulation of Aptamer Activity with Effector-Responsive Hairpin Oligonucleotides - a podcast by SAGE Publications Ltd.

Aptamers are oligonucleotides that can bind to various nonnucleic acid molecular targets in a high affinity and specificity. As an emerging class of therapeutic agents, aptamers offer an unparalleled advantage over other classes of therapeutic agents: the possibility to rationally regulate the therapeutic activity of aptamers.

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