153: Xenotransplants: The Man With a Pig Heart - a podcast by The Sci Guys

Human organs are in short supply - but this year scientists decided to genetically modify a pig heart to save the life of a man with terminal heart disease. This xentoransplant is brand new science & had never been done before. This week we go over the crazy experiments and mind-blowing science that led to this medical marvel.



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References & Further Reading

Xenotransplantation

https://archive.bio.org/articles/xenotransplantation-benefits-and-risks-special-organ-transplantation

https://www.omixon.com/brief-history-xenotransplantation/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684730/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246856/

https://www.who.int/ethics/en/ETH_Nuffiled_xenotransplantation.pdf

https://www.frontiersin.org/articles/10.3389/fimmu.2019.03060/full

https://www.fda.gov/vaccines-blood-biologics/xenotransplantation

https://www.groomers-online.com/professional-c1/scissors-c22/left-handed-scissors-c265/groomers-elite-45-straight-left-handed-bull-nosed-scissors-p755

https://pubmed.ncbi.nlm.nih.gov/34697231/



Organ Donation & Transplants

https://www.organdonation.nhs.uk/helping-you-to-decide/about-organ-donation/statistics-about-organ-donation/

https://www.organdonation.nhs.uk/helping-you-to-decide/about-organ-donation/living-donation/

https://www.nhsbt.nhs.uk/what-we-do/transplantation-services/organ-donation-and-transplantation/



First Pig Heart Transplant

https://www.economist.com/science-and-technology/2022/01/15/the-science-behind-the-first-successful-pig-to-human-heart-transplant

https://www.bbc.co.uk/news/world-us-canada-59944889.amp

https://www.nature.com/articles/d41586-022-00111-9

https://secure.jbs.elsevierhealth.com/action/consumeSsoCookie?redirectUri=https%3A%2F%2Fwww.thelancet.com%2Faction%2FconsumeSharedSessionAction%3FJSESSIONID%3DaaaBetSmryb39fIGYw37x%26MAID%3DcerwNnXJRoDD37sdGKDXfw%253D%253D%26SERVER%3DWZ6myaEXBLFD8VbcQEfOcg%253D%253D%26I2KBRCK%3D1%26ORIGIN%3D695817921%26RD%3DRD%26exp%3DTEn4cY9Dbt214rWTophWGQ%25253D%25253D&code=null&acw=Secure;SameSite=None&utt=

https://amp.theguardian.com/science/2022/feb/03/german-researchers-to-breed-pigs-for-human-heart-transplants