June 23, 2020 - a podcast by COVID19LST

On today's episode we discuss:

—Climate:  A study conducted by the Center for Disease Control and Prevention of 2,402 Americans in May found widespread support of the implementation of public health orders such as stay-at-home orders, use of face coverings, and business closures, in response to the COVID-19 pandemic.

—Epidemiology:  A cross-sectional study in Indianapolis found that 3.1% of 2,953 asymptomatic adults tested positive for SARS-CoV-2 by nasopharyngeal swab testing. Of the 81 SARS-CoV-2 positive participants who completed a follow-up interview, 71.6% remained asymptomatic at 14 days while the other 28.4% reported one or more symptoms.

—Management:  A group of researchers in Toronto suggest SARS-CoV-2 disruption of the renin angiotensin aldosterone system (RAAS) leads to an endothelial imbalance that leaves the endothelium susceptible to inflammation, vasoconstriction, platelet activation, and thrombosis thus playing a major role in the disease.

—Diagnosis and Treatment:  A study of 190 patients found that oropharyngeal/nares swabs and nasopharyngeal swabs had sensitivities of 91.7% and 94.4%, respectively, suggesting that oropharyngeal/nares sampling, which may be more readily available during the COVID-19 pandemic, is an effective alternative to nasopharyngeal swabs in ambulatory settings

—Mental Health and Resilience: Psychiatrists and addiction medicine experts from Germany conducted a survey of 2,102 German citizens and found that 34.7% of respondents have consumed “more or much more” alcohol during the pandemic compared to their baseline, and indicated that increased alcohol consumption during this time is associated with lower educational status and increased stress.

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