May 5, 2020 - a podcast by COVID19LST

Your daily COVID-19 LST Report:

— The Seattle Flu Study is a multi-institutional, community-wide surveillance project initially intended to track data from influenza that began testing nasal swabs for COVID-19 in any patient with respiratory symptoms. From January 1-March 9, they found that 1.1% of participants tested positive for COVID-19 in 30% of patients seeking clinical care.

— In a retrospective analysis of over 3,000 COVID-19 patients, researchers found that RNA-based diagnostic testing methods lacked negative predictive value, though they were useful indicators for clinical course, pattern, and prognosis.

— Convalescent plasma transfusion was found to be safe, clinically effective, and beneficial in reducing mortality in five studies of 27 COVID-19 patients.

— Key laboratory tests recommended for COVID-19 patients are:

• CBC with differential
  
  


• Acute phase inflammatory biomarkers
  
  


• Kidney, liver, and cardiac injury biomarkers
  
  


• Indicators of improvement: CRP/procalcitonin
  
  


• Prognostic biomarkers like D-dimer values
  
  


• Sequential organ failure assessment.

— Visit COVID19LST.org for our full report with links to the articles.

— Reach out to us at: contact@covid19lst.org

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