May 6, 2020 - a podcast by COVID19LST

Your daily COVID-19 LST Report:

— An analysis of ultraviolet-C (UVC) decontamination of N95 respirators coated in MRSA or a bacteriophage found high variability of viral or bacterial persistence by different locations on the respirators and reduction levels that did not meet the criteria for decontamination.

— The cellular protease Furin, was found to cleave the SARS-CoV-2 S protein S1/S2 multibasic site, which mediates cell to cell fusion and entry into human lung cells. Thus, Furin is suggested for therapeutic potential.

— In a recent case report, a 47 year old man died from small bowel perforation from acute bowel ischemia secondary to COVID-19.  The ischemia was characterized by yellow discoloration, necrosis, with patent mesenteric vasculature, which draws attention to direct tissue injury in the gastrointestinal tract from SARS-CoV-2 and possible microvascular thrombosis.

— Of the 55 imported cases of COVID-19 detected through mandatory testing in Brunei, almost half were asymptomatic upon entry suggesting that symptom-based screening at entry points will likely miss a large proportion of cases.

— Visit COVID19LST.org for our full report with links to the articles.

— Reach out to us at: contact@covid19lst.org

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