October 29, 2020 - a podcast by COVID19LST

In today's episode we discuss:

—Epidemiology: An online survey of 1777 pregnant and postpartum women conducted in Japan found high prevalence of prenatal anhedonia, depression, and anxiety (17%; evaluated via Edinburgh Postnatal Depression Scale [EDPS]), which was positively correlated with perceived risk of contracting COVID-19, concerns regarding financial effects of the pandemic, and lack of social support during the COVID-19 pandemic.

—Understanding the Pathology: A prospective observational study conducted at Infanta Leonor University Hospital in Madrid, Spain from analyzed 26 COVID-19 positive patients with pulmonary embolisms (PE) who were screened for deep vein thrombosis (DVT) via compression ultrasound and found just 2 had evidence of DVT on compression ultrasound, one in their left popliteal vein and the other in their left femoral vein.

—Transmission & Prevention: Researchers from Brazil analyzed results of 4,353 RT-PCR SARS-CoV-2 tests and 2,275 SARS-CoV-2 antibody tests of patients with known blood types collected before June 22, 2020 and found an insignificantly higher infection rate in individuals with type A blood compared to type O blood, indicating that ABO blood types may have a less direct effect on rates of SARS-CoV-2 infections than previously predicted and that altered rates of infection may be mediated by other qualities of the population being studied.

—Management: A prospective observational study conducted in Spain examined the complete blood count (CBC) and cell population data (CPD), via XN20 analyser, of 153 COVID-19 patients and 72 bacterial infection patients and found neutrophil-to-lymphocyte ratio (NLR) values helped distinguish COVID-19 and bacterial infections (positive predictive value 74.1%, negative predictive value 97.1%), suggesting that NLR, along with other CBC and CPD values, may assist in accurately differentiating infectious etiologies during the COVID-19 pandemic.

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