In this episode we discuss:
Why hypothyroidism is not the root cause of your issues
Why TSH on its own is not a good marker of thyroid status
The importance of thyroid hormones for sex hormone production, gut health, and immune function
T3’s effects on autophagy, mitochondrial biogenesis, and uncoupling
Whether low thyroid activity is beneficial for longevity and aging and when a high TSH may be a good sign
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Click here to check out the show notes: https://www.jayfeldmanwellness.com/ep-95-hypothyroidism-in-context-thyroid-hormone-basics-hypothyroidism-part-1/
Timestamps:
0:00 – intro
1:19 – an introduction to hypothyroidism and common symptoms of hypothyroidism
9:02 – the broader biological context of hypothyroidism and hypothyroidism as a low metabolic state
12:45 – why hypothyroidism is not the root cause
16:23 – the basics of the different thyroid hormones and their regulation
19:54 – the hypothalamic-pituitary-thyroid axis and the nuances within the negative feedback loops
24:45 – the basics of thyroid hormone production
29:37 – the basics of thyroid hormone conversion
35:17 – the larger context of thyroid hormone production and conversion
38:58 – the basics of thyroid hormone transport
41:44 – the basics of thyroid hormone uptake
46:23 – the nutrients involved in thyroid hormone production and conversion
50:26 – the cellular effects of T3 (metabolic stimulation, uncoupling, autophagy, mitochondrial biogenesis, steroidogenesis from cholesterol)
57:29 – the effects of T3 on gut health, immune function, and aging
1:03:08 – whether low thyroid activity is beneficial for longevity and aging and when a high TSH may be a good sign
1:08:41 – the relationship between vitamin A and thyroid hormones
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