Podcasts by The Inner Workings of Cells, Winter 2008
Cellular function lies at the root of all complex and simple biological systems. This course will expose you to the fundamental mechanisms that allow cells to maintain the system of proteins and biomolecules required for them to replicate with high fidelity, to maintain stable functional states, to differentiate in response to external cues and to ultimately form complex organizations of cells (i.e., tissues). We will apply an experimental approach to a classic problem in cell biology. We will master “blackboard” experimental techniques to allow us to explore the remarkable transformation of a monolayer of cells after being “wounded.” Under such conditions, cells surrounding the wound change their organization and programming in order to migrate, divide, and differentiate to fill in the wound.
Further podcasts by Ken Kaplan
Podcast on the topic Wissenschaft
All episodes
Review for Final Exam from 2008-03-21T07:00
Review for Final Exam: This class covers all topics discussed in the course, with an emphasis on cell signaling.
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Cell Signaling&Cancer Cells from 2008-03-17T07:00
Lecture 28: The instructor reviews some major pathways dealing with signal transduction and an application of principles learned to cancerous cells.
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Signal Transduction from 2008-03-14T07:00
Lecture 27: Kaplan continues his discussion of signal transduction, the role of signals in cell migration, and the ability of cells to see which direction to move.
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Cell Signaling from 2008-03-10T07:00
Lecture 25: This class is a wrap-up of cell division and checkpoints in the regulatory cycle, and introduction to how cells interpret various biochemical signals.
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Cell Division from 2008-03-07T08:00
Lecture 24: Students learn more about cell division, and introduction to cell checkpoints along the regulatory cycle.
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Review for Midterm 2 from 2008-03-04T08:00
Review for Midterm 2: This covers protein trafficking, the cytoskeleton and cell division.
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Regulation of Cell Division from 2008-03-03T08:00
Lecture 22: This is a continued discussion of the regulation of cell division -- how mitosis is coordinated within the cell.
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Microtubles and Cell Motility from 2008-02-27T08:00
Lecture 20: Kaplan wraps up of the cytoskeleton, relation of microtubles to cell motility, introduction to cell division.
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Microtubules from 2008-02-25T08:00
Lecture 19: In this class, microtubule dynamics and stability and how these aspects of microtubules are controlled to produce energy and force for processes such as mitosis.
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Intermediate Filaments from 2008-02-22T08:00
Lecture 18: In a continued discussion of intermediate filaments, Kaplan talks about their relation to other cytoskeletal filaments and microtubule dynamics.
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Filament Dynamics from 2008-02-15T08:00
Lecture 16: Kaplan continues talking about actin, how it can lead to cell motility, as well as how it and other filament dynamics are regulated within the cell.
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Cell Movement from 2008-02-13T08:00
Lecture 15: Kaplan discusses how cytoskeletal elements of a cell are involved in cell movement, such as actin.
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Review for Midterm 1 from 2008-02-10T08:00
Review for Midterm 1: This class covers cell biology techniques, cell compartmentalization, cell membranes, the secretory pathway and protein trafficking.
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Review of Protein Trafficking from 2008-02-08T08:00
Lecture 14: The professor wraps up protein trafficking and non-secretory transport.
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Vesicular Transport from 2008-02-04T08:00
Lecture 12: Kaplan gives an in-depth discussion of in-vitro coupled translation and translocation.
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ER Reactions from 2008-02-01T08:00
Lecture 11: Kaplan reviews glycosylation and gives an in-depth look at the work done to understand protein translocation and examples of protein trafficking.
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Protein Movement from 2008-01-30T08:00
Lecture 10: In this continued discussion on protein translocation, Kaplan gives emphasis to glycosylation and the Scavenger pathway.
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Secretory Pathway from 2008-01-25T08:00
Lecture 08: Kaplan talks about how various proteins are directed to certain areas within the cell and to the plasma membrane.
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Membrane Proteins from 2008-01-23T08:00
Lecture 07: Kaplan discusses the various classes of membrane proteins and movement of molecules across the membrane.
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Membrane Reactions from 2008-01-18T08:00
Lecture 06: This is a continued discussion of cellular membranes and their various functions in biochemical reactions.
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Cell Membranes from 2008-01-16T08:00
Lecture 05: This class wraps up of tools to study complex cellular behavior (including microscopy), and introduces membrane proteins.
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Subcellular Fractionation from 2008-01-14T08:00
Lecture 04: How to use subcellular fractionation and other techniques to study complex cellular processes and molecules.
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Antibodies from 2008-01-11T08:00
Lecture 03: This class reviews what characteristics a gene needs to be"necessary and sufficient."A discussion of antibodies and their application to various techniques of cell biologists.
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Goals of Cell Biology from 2008-01-09T08:00
Lecture 02: Goals of cell biologists and the overall course plan are discussed and students introduced to the question of how to study cells.
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Class Overview from 2008-01-07T08:00
Lecture 01: Kaplan discusses class mechanics, student questions and the central questions of cell biology.
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