Podcasts by Two Scientists Walk Into a Bar
From research on cancer vaccines to why we feel pain, scientists are tackling some of the biggest challenges in human biology. Want to find out what they’re working on? Pull up a stool for "Two Scientists Walk Into a Bar." Subscribe below to catch each episode as it goes live.
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S4E03: Take A Deep Breath: Treating Asthma from 2021-12-01T15:23:56
Taking a deep breath can seem like a simple process; however, for millions of people with asthma, inflammation of the airways could make it difficult to breathe. While current treatments help manag...
ListenS4E02: Demystifying MS: The Intersection Of Immunology And Neuroscience from 2021-09-15T14:02:26
Our understanding of what causes multiple sclerosis (MS) has transformed over the last few decades. While discoveries of the cell types involved in MS progression — both immune and brain — have led...
ListenMeet The Hosts of Season Four from 2021-07-13T14:04:42
Two Scientists Walk Into A Bar is back for a fourth season with new hosts, Maria Wilson and Danielle Mandikian! Get to know the new hosts and preview this season. Subscribe today so you don’t miss ...
ListenS4E0: Studying the Symphony of Cells from 2021-01-26T13:54:28
Cells are the basic unit of life, with a remarkable ability to sense their environment, process information and adapt accordingly. With 37.2 trillion cells in the human body, there remains plenty f...
ListenS3E06: From Fly Genetics to Human Aging: Insights into Regenerative Medicine from 2020-01-24T17:56:35
The biological mysteries of age-related diseases have intrigued scientists for decades. In recent years, our expansive knowledge of genetics, thanks to the humble fruit fly, has opened our eyes to ...
ListenS3E05: Beyond Biomarkers: Calling All Data Scientists from 2019-12-13T18:00:15
In Season 1, we talked about using biomarkers and big data to match patients with the best treatment for their disease. In this episode, Jane sits down with David Shames, Senior Director of Cancer ...
ListenS3E04: A Look Into the Eye from 2019-08-09T22:21:39
Our eyes are our windows to the world, but what happens when those windows start to fade or disappear? To understand how the eye works, scientists are combining developments in imaging and genetics...
ListenS3E03: Cancer: When Cells Go Rogue from 2019-03-12T17:13:44
It’s easy to think of cancer as an invader to the body. But in reality, it’s simply the result of a few proofreading errors in DNA replication that occur over time when cells divide. In Episode 3, ...
ListenS3E02: Fire in the Gut: IBD Explained from 2019-02-06T23:20:55
Last episode, Jane and colleagues unraveled the intricacies of the human microbiome. This week, Jane chats with Mary Keir, Senior Scientist, Biomarker Discovery OMNI, to learn what happens during i...
ListenS3E01: Unraveling the Microbiome from 2019-01-04T16:40:37
Our bodies are full of bacteria - pounds of them actually. We’re kicking off Season 3 with a closer look at the human microbiome and what happens when the synergistic relationship between our cells...
ListenSeason Three Teaser from 2019-01-02T16:55:56
Two Scientists Walk Into a Bar is back for a third season with host Jane Grogan chatting with scientists who are leading the charge to understand complex diseases. This season will tackle a range o...
ListenS2E08: Why You Should Study Immunology from 2018-04-11T22:33:44
So far this season we’ve talked about the immune system a lot – how immune cells communicate, traffic along connective tissue, and invasive tumors. But what actually is the immune system? What’s it...
ListenS2E07: The Therapeutic Window from 2018-03-19T18:30:44
Pharmacology is the study of how a medicine works in the body, which is a critical step in understanding what medicines people should be given, and at what dose and schedule. As we learn more about...
ListenS2E06: The Polarizing World of Neurons from 2018-02-26T22:06:57
Neurons, the cells that make up our brain, are some of the most unique cells in our bodies. The complex nature of how they communicate leads to everything we say, think, or do. That complexity make...
ListenS2E05: Why Cells Die from 2018-01-31T18:56:10
The lifecycle of a cell mirrors our own lives – cells live and die as we do. It would be easy to think of cell death, or apoptosis, as a negative action, but the death of a cell is actually critica...
ListenS2E04: Viruses, Bacteria and How to Beat Them from 2018-01-03T22:39:57
Despite the best efforts of the human immune system, viruses and bacteria are constantly evolving to find new ways to breach our bodies’ natural defenses. Over the years, scientists have stepped in...
ListenS2E03: What’s in a Pill? from 2017-11-16T19:52:13
Chemistry is all around us – from the air we breathe, to the food we eat, to the medicine we take when we’re sick. And for the researchers working to figure out how to make those medicines, chemist...
ListenS2E02: Proteins: Seeing is Believing from 2017-10-25T18:18:51
The world of proteins is a minuscule and elegant ballet. Recent advances in imaging techniques have given us unprecedented views into this microscopic world, which could help us design better targe...
ListenS2E01: Connective Tissue: The Hidden Metropolis from 2017-09-27T23:02:06
If your body was a city, then connective tissue would be the infrastructure tying everything together. It’s a hidden universe that helps many types of cells talk to each other and helps us fight di...
ListenSeason Two Teaser from 2017-09-12T17:31:32
Jane Grogan and her producer Wellington Bowler are back for a second season of Two Scientists Walk Into a Bar. After a summer hiatus, Jane is eager to take on a new season of topics, including the ...
ListenS1E08: Designing Early Stage Clinical Trials from 2017-03-27T21:30:04
Designing a clinical trial is fascinatingly complex. There are dozens of variables that could influence the ability of any given trial to be successful. Navigating this complexity is truly a scienc...
ListenS1E07: Biomarkers and Big Data from 2017-02-27T18:20:39
Each person’s cancer is unique, so trying to match the right treatment to the right person is one of cancer biology’s biggest remaining challenges. In our latest episode, Priti Hegde, Director of O...
ListenS1E06: Continuing the Fight Against Breast Cancer from 2017-01-11T20:35:24
Some types of breast cancer can become “addicted” to estrogen signaling, so treatments that target the estrogen receptor were once thought to be a magic bullet against this disease. But breast canc...
ListenS1E05: The Search for Super Antibiotics from 2016-12-14T22:50:02
Bacteria are remarkably fast shape-shifters. As soon as we develop new antibiotics against them, they mutate, leading to drug-resistant strains the world has never seen before. This could mean that...
ListenS1E04: The Degenerating Brain from 2016-11-30T22:29:32
In 1848 an explosion launched an iron rod through Phineas Gage’s brain. He miraculously survived, but wasn’t the same person, giving scientists the first clues into how neurodegeneration can affect...
ListenS1E03: How Your Cells Talk to Each Other (Hint: Not by Cell Phones) from 2016-11-16T23:03:57
Communication is the key to good relationships. That’s true not only for people, but for our cells as well. If cellular communication goes wrong, your brain may stop processing information, or your...
ListenS1E02: Ouch! Our Bodies and Pain from 2016-11-02T22:44:10
Pain is actually good for us. Until it’s not. Discovering how to fight chronic pain, while leaving acute pain intact, is no easy venture. Join Morgan Sheng as he takes us on a tour of the different...
ListenS1E01: Cancer and Your Immune System from 2016-10-20T00:26:03
A revolution in cancer care is happening right now. In our debut episode, Jane Grogan sits down with Ira Mellman, one of the world’s foremost experts in the field of cancer immunotherapy, about the...
ListenPodcast Introduction from 2016-10-06T19:28:08
The only thing Jane Grogan loves more than doing science is talking about it. In addition to being an accomplished scientist leading research on inflammation, autoimmunity and tumor immunobiology, ...
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